Action potential morphology heterogeneity in the atrium and its effect on atrial reentry: A two-dimensional and quasi-three-dimensional study

Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences

Volumn 364, Issue 1843, 2006, Pages 1349-1366

  Kuo, Samuel R ^a   Trayanova, Natalia A ^a  

^a TULANE UNIVERSITY   (United States)

Author keywords

Action potential morphology; Atrial fibrillation; Computer simulations; Crista terminalis; Spiral wave

Indexed keywords

EID: 33745137828     PISSN: 1364503X     EISSN: None     Source Type: Journal    
DOI: 10.1098/rsta.2006.1776     Document Type: Conference Paper

References (48)

1. Allessie, M. A. 1999 Atrial fibrillation-induced electrical remodeling in humans: what is the next step? Cardiovasc. Res. 44, 10-12. (doi:10.1016/S0008- 6363(99)00244-8)
2. Allessie, M. A., Bonke, F. I. & Schopman, F. J. 1973 Circus movement in rabbit atrial muscle as a mechanism of tachycardia. Circ. Res. 33, 54-62.
3. Beaumont, J., Davidenko, N., Davidenko, J. M. & Jalife, J. 1998 Spiral waves in two-dimensional models of ventricular muscle: formation of a stationary core. Biophys. J. 75, 1-14. (doi:10.1016/S0301-4622(98)00194-X)
4. Bourn, D. W., Maleckar, M. M., Rodriguez, B. & Trayanova, N. A. 2006 Mechanistic enquiry into the effect of rapid pacing rate on the upper limit of vulnerability. Phil. Trans. R. Soc. A 364, 1333-1348. (doi:10.1098/rsta.2006. 1775)
5. Boutjdir, M., Le Heuzey, J. Y., Lavergne, T., Chauvaud, S., Guize, L., Carpentier, A. & Peronneau, P. 1986 Inhomogeneity of cellular refractoriness in human atrium: factor of arrhythmia? Pacing Clin. Electrophysiol. 9, 1095-1100.
6. Cabo, C., Pertsov, A. M., Baxter, W. T., Davidenko, J. M., Gray, R. A. & Jalife, J. 1994 Wave-front curvature as a cause of slow conduction and block in isolated cardiac muscle. Circ. Res. 75, 1014-1028.
7. Chen, J., Mandapati, R., Berenfeld, O., Skanes, A. C., Gray, R. A. & Jalife, J. 2000 Dynamics of wavelets and their role in atrial fibrillation in the isolated sheep heart. Cardiovasc. Res. 48, 220-232. (doi:10.1016/S0008- 6363(00)00177-2)
8. Cohen, G. I., White, M., Sochowski, R. A., Klein, A. Z., Bridge, P. D., Stewart, W. J. & Chan, K. L. 1995 Reference values for normal adult transesophageal echocardiographic measurements. J. Am. Soc. Echocardiogr. 8, 221-230. (doi:10.1016/80894-7317(05)80031-8)
9. Courtemanche, M. 1996 Complex spiral wave dynamics in a spatially distributed ionic model of cardiac electrical activity. Chaos 6, 519-524. (doi:10.1063/1.166206)
10. Ellis, W. S., SippensGroenewegen, A., Auslander, D. M. & Lesh, M. D. 2000 The role of the crista terminalis in atrial flutter and fibrillation: a computer modeling study. Ann. Biomed. Eng. 28, 742 754. (doi:10.1114/1.1289456)
11. Fenclon, G., Shepard, R. K. & Stambler, B. S. 2003 Focal origin of atrial tachycardia in dogs with rapid ventricular pacing-induced heart failure. J. Cardiovasc. Electrophys. 14, 1093-1102. (doi:10.1046/j.1540-8167.2003.03110. x)
12. Feng, J., Yue, L., Wang, Z. & Nattel, S. 1998 Ionic mechanisms of regional action potential heterogeneity in the canine right atrium. Circ. Res. 83, 541-551.
13. Fenton, F. H., Cherry, E. M., Hastings, H. M. & Evans, S. J. 2002 Multiple mechanisms of spiral wave breakup in a model of cardiac electrical activity. Chaos 12, 852-892. (doi:10.1063/1.1504242)
14. Garrey, W. 1914 The nature of fibrillary contraction of the heart: its relation to tissue mass and form. Am. J. Physiol. 33, 397-414.
15. Iyer, A. N. & Gray, R. A. 2001 An experimentalist's approach to accurate localization of phase singularities during reentry. Ann. Biomed. Eng. 29, 47-59. (doi:10.1114/1.1335538)
16. Jalife, J., Berenfeld, O. & Mansour, M. 2002 Mother rotors and fibrillatory conduction: a mechanism of atrial fibrillation. Circ. Res. 54, 204-216.
17. Kalman, J. M., Olgin, J. E., Karch, M. R., Hamdan, M., Lee, R. J. & Lesh. M. D. 1998 'Cristal tachycardias': origin of right atrial tachycardias from the crista terminalis identified by intracardiac echocardiography. J. Am. Coll. Cardiol. 31. 451-459. (doi:10.1016/S0735-1097(97)00492-0)
18. Karma, A. 1994 Electrical alternans and spiral wave breakup in cardiac tissue. Chaos 4, 461-472. (doi:10.1063/1.166024)
19. Kneller, J. et al. 2005 Mechanisms of atrial fibrillation termination by pure sodium channel blockade in an ionically-realistic mathematical model. Circ. Res. 96. c35-e47. (doi:10.1161/01.RES.0000160709.49633.2b)
20. Kobayashi, T. et al. 2003 Impaired longitudinal conduction in crista terminalis is necessary for sustenance of experimental atrial flutter. Pacing Clin. Electrophysiol. 26, 2008-2015. (doi:10.1046/j.1460-9592.2003.00310.x)
21. Larson, C., Dragnev, L. & Trayanova, N. 2003 Analysis of electrically-induced reentrant circuits in a sheet of myocardium. Ann. Biomed. Eng. 31, 768-780. (doi:10.1114/1.1581289)
22. Mandapati, R., Asano, Y., Baxter, W. T., Gray, R., Davidenko, J. & Jalife, J. 1998 Quantification of effects of global ischemia on dynamics of ventricular fibrillation in isolated rabbit heart. Circulation 98, 1688-1696.
23. Mandapati, R., Skanes, A., Chen, J., Berenfeld, O. & Jalife, J. 2000 Stable microreentrant sources as a mechanism of atrial fibrillation in the isolated sheep heart. Circulation 101, 194-199.
24. Mizumaki, K., Fujiki, A., Nagasawa, H., Nishida, K., Sakabe, M., Sakurai, K. & Inoue, H. 2002 Relation between transverse conduction capability and the anatomy of the crista terminalis in patients with atrial flutter and atrial fibrillation. Circ. J. 66, 1113-1118. (doi:10.1253/circj.66.1113)
25. Moe, G. K. & Ablidskov, J. A. 1959 Atrial fibrillation as a self-sustaining arrhythmia independent of focal discharge. Am. Heart J. 58, 59-70. (doi:10.1016/0002-8703(59)90274-1)
26. Pertsov, A. M., Davidenko, J. M., Salomonsz, R., Baxter, W. T. & Jalife, J. 1993 Spiral waves of excitation underlie reentrant activity in isolated cardiac muscle. Circ. Res. 72, 631-650.
27. Qi, A., Yueng-Lai-Wah, J. A., Xiao, J. & Kerr, C. R. 1994 Regional differences in rabbit atrial repolarization: importance of transient outward current. Am. J. Physiol. 266, H643-H649.
28. Qu, Z. L., Weiss, J. N. & Garfinkel, A. 1999 Cardiac electrical restitution properties and stability of reentrant spiral waves: a simulation study. Am. J. Physiol. 276, H269-H283.
29. Qu, Z. L., Xie, F. G., Garfinkel, A. & Weiss, J. N. 2000 Origins of spiral wave meander and breakup in a two-dimensional cardiac tissue model. Ann. Biomed. Eng. 28, 755-771. (doi:10.1114/1.1289474)
30. Ramirez, R., Nattel, S. & Courtemanche, M. 2000 Mathematical analysis of canine atrial action potentials: rate, regional factors, and electrical remodelling. Am. J. Physiol. 279, H1767-H1785.
31. Rogers, J. M. 2002 Wave front fragmentation due to ventricular geometry in a model of the rabbit heart. Chaos 12, 779-787. (doi:10.1063/1.1483956)
32. Roithinger, F. X., Karch, M. R., Steiner, P. R., SippensGroenewegen, A. & Lesh, M. D. 1999 The spatial dispersion of atrial refractoriness and atrial fibrillation vulnerability. J. Interv. Card. Electrophysiol. 3, 311-319. (doi:10.1023/A:1009844132736)
33. Sampson, K. J. & Henriquez, C. S. 2002 Interplay of ionic and structural heterogeneity on functional action potential duration gradients: implications for arrhythmogenesis. Chaos 12, 819-828. (doi:10.1063/1.1497735)
34. Schumacher, B., Jung, W., Schmidt, H., Fischenbeck, C., Lewalter, T., Hagendorff, A., Omran, H., Wolpert, C. & Luderitz, B. 1999 Transverse conduction capabilities of the crista terminalis in patients with atrial flutter and atrial fibrillation. J. Am. Coll. Cardiol. 34, 363-373. (doi:10.1016/80735-1097(99)00211-9)
35. Shoji, S., Adaniya, H., Numano, F. & Hiraoka, M. 2000 Factors determining clockwise and counterclockwise conduction patterns in atrial reentrant tachycardias: a rabbit model of atrial flutter. J. Cardiovasc. Electrophys. 11, 311-323.
36. Solovyova, O., Katsnelson, L. B., Konovalov, P., Lookin, O., Moskvin, A. S., Protsenko, Yu. L., Vikulova, N., Kohl, P. & Markhasin, V. S. 2006 Activation sequence as a key factor in spatiotemporal optimization of myocardial function. Phil. Trans. R. Soc. A 364, 1367-1383. (doi:10.1098/rsta.2006.1777)
37. Spach, M. S., Dolber, P. C. & Anderson, P. A. W. 1989a Multiple regional differences in cellular properties that regulate repolarization and contraction in the right atrium of adult and newborn dogs. Circ. Res. 65, 1594-1611.
38. Spach, M. S., Dolber, P. C. & Heidlage, J. F. 1989b Interaction of inhomogeneities of repolarization with anisotropic propagation in dog atria: a mechanism for both preventing and initiating reentry. Circ. Res. 65, 1612-1631.
39. Tai, C. T., Chen, S. A., Chen, Y. J., Yu, W. C., Hsieh, M. H., Tsai, C. F., Chen, C. C., Ding, Y. A. & Chang, M. S. 1998 Conduction properties of the crista terminalis in patients with typical atrial flutter: basis for a line of block in the reentrant circuit. J. Cardiovasc. Electrophys. 9, 811-819.
40. Ten Tusscher, K. H. & Panfilov, A. V. 2003 Reentry in heterogeneous cardiac tissue described by the Luo-Rudy ventricular action potential model. Am. J. Physiol. 284, H542-H548.
41. Vaidya, D., Morley, G. E., Samie, F. H. & Jalife, J. 1999 Reentry and fibrillation in the mouse heart, a challenge to the critical mass hypothesis. Circ. Res. 85, 174-181.
42. Vigmond, E. J., Ruckdeschel, R. & Trayanova, N. 2001 Reentry in a morphologically realistic atrial model. J. Cardiovasc. Ekctrophysiol. 12, 1046-1054. (doi:10.1046/j.1540-8167.2001.01046.x)
43. Vigmond, E. J., Tsoi, V., Kuo, S., Arevalo, H., Kneller, J., Nattel, S. & Trayanova, N. 2004 The effect of vagally induced dispersion of action potential duration on atrial arrhythmogenesis. Heart Rhythm 1, 334-344. (doi:10.1016/.j.hrthm.2004.03.077)
44. Wijffels, M. C. Kirchhof, C. J., Dorland, R., Power. J. & Allessie, M. A. 1997 Electrical remodeling due to atrial fibrillation in chronically instrumented conscious goats: roles of neurohumoral changes, ischemia, atrial stretch, and high rate of electrical activation. Circulation 96, 3710-3720.
45. Xie, F., Qu, Z., Garfinkel. A. & Weiss, J. X. 2001 Electrophysiological heterogeneity and stability of reentry in simulated cardiac tissue. Am. J. Physiol. 28, H535-H545.
46. Yamabe, H., Misumi, I., Fukushima, H., Ueno, K., Kimura, Y. & Hokamura, Y. 2002 Conduction properties of the crista terminalis and its influence on the right atrial activation sequence in patients with typical atrial flutter. Pacing Clin. Electrophysiol. 25, 132-141. (doi:10.1046/j.1400- 9592.2002.00132.x)
47. Yamashita, T., Nakajima, T., Hazama, H., Hamada, E., Murakawa, Y., Sawada, K. & Omata, M. 1995 Regional differences in transient outward current density and inhomogeneities of repolarization in rabbit right atrium. Circulation 92, 3061-3069.
48. Zykov, V. S. 1987 Simulation of wave processes in excitable media. Manchester, England: Manchester University Press.