Mapping Functional Domains of Chloride Intracellular Channel (CLIC) Proteins in Vivo

Journal of Molecular Biology

Volumn 359, Issue 5, 2006, Pages 1316-1333

  Berry, Katherine L ^a   Hobert, Oliver ^a  

^a NewYork Presbyterian Hospital   (United States)

Author keywords

C. elegans; CLIC; ion channel; membrane targeting

Indexed keywords

CELL PROTEIN; CHLORIDE INTRACELLULAR CHANNEL PROTEIN; CYSTEINE; GLUTATHIONE TRANSFERASE; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CAENORHABDITIS ELEGANS; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; IN VIVO STUDY; MUTATIONAL ANALYSIS; NEMATODE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN TARGETING; SEQUENCE ANALYSIS; STRUCTURAL HOMOLOGY;

CAENORHABDITIS ELEGANS; INVERTEBRATA; VERTEBRATA;

EID: 33745137113     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2006.04.046     Document Type: Article

References (56)

1. Dulhunty A., Gage P., Curtis S., Chelvanayagam G., and Board P. The glutathione transferase structural family includes a nuclear chloride channel and a ryanodine receptor calcium release channel modulator. J. Biol. Chem. 276 (2001) 3319-3323
2. Valenzuela S.M., Martin D.K., Por S.B., Robbins J.M., Warton K., Bootcov M.R., et al. Molecular cloning and expression of a chloride ion channel of cell nuclei. J. Biol. Chem. 272 (1997) 12575-12582
3. Chuang J.Z., Milner T.A., Zhu M., and Sung C.H. A 29 kDa intracellular chloride channel p64H1 is associated with large dense-core vesicles in rat hippocampal neurons. J. Neurosci. 19 (1999) 2919-2928
4. Fernandez-Salas E., Sagar M., Cheng C., Yuspa S.H., and Weinberg W.C. p53 and tumor necrosis factor alpha regulate the expression of a mitochondrial chloride channel protein. J. Biol. Chem. 274 (1999) 36488-36497
5. Tonini R., Ferroni A., Valenzuela S.M., Warton K., Campbell T.J., Breit S.N., and Mazzanti M. Functional characterization of the NCC27 nuclear protein in stable transfected CHO-K1 cells. Faseb J. 14 (2000) 1171-1178
6. Berry K.L., Bulow H.E., Hall D.H., and Hobert O. A C. elegans CLIC-like protein required for intracellular tube formation and maintenance. Science 302 (2003) 2134-2137
7. Berryman M.A., and Goldenring J.R. CLIC4 is enriched at cell-cell junctions and colocalizes with AKAP350 at the centrosome and midbody of cultured mammalian cells. Cell Motil. Cytoskeleton 56 (2003) 159-172
8. Schlesinger P.H., Blair H.C., Teitelbaum S.L., and Edwards J.C. Characterization of the osteoclast ruffled border chloride channel and its role in bone resorption. J. Biol. Chem. 272 (1997) 18636-18643
9. Ronnov-Jessen L., Villadsen R., Edwards J.C., and Petersen O.W. Differential expression of a chloride intracellular channel gene, CLIC4, in transforming growth factor-beta1-mediated conversion of fibroblasts to myofibroblasts. Am. J. Pathol. 161 (2002) 471-480
10. Fernandez-Salas E., Suh K.S., Speransky V.V., Bowers W.L., Levy J.M., Adams T., et al. mtCLIC/CLIC4, an organellular chloride channel protein, is increased by DNA damage and participates in the apoptotic response to p53. Mol. Cell Biol. 22 (2002) 3610-3620
11. Suh K.S., Mutoh M., Gerdes M., Crutchley J.M., Mutoh T., Edwards L.E., et al. Antisense suppression of the chloride intracellular channel family induces apoptosis, enhances tumor necrosis factor {alpha}-induced apoptosis, and inhibits tumor growth. Cancer Res. 65 (2005) 562-571
12. Suh K.S., Mutoh M., Nagashima K., Fernandez-Salas E., Edwards L.E., Hayes D.D., et al. The organellular chloride channel protein CLIC4/mtCLIC translocates to the nucleus in response to cellular stress and accelerates apoptosis. J. Biol. Chem. 279 (2004) 4632-4641
13. Novarino G., Fabrizi C., Tonini R., Denti M.A., Malchiodi-Albedi F., Lauro G.M., et al. Involvement of the intracellular ion channel CLIC1 in microglia-mediated beta-amyloid-induced neurotoxicity. J. Neurosci. 24 (2004) 5322-5330
14. Landry D.W., Akabas M.H., Redhead C., Edelman A., Cragoe Jr. E.J., and Al-Awqati Q. Purification and reconstitution of chloride channels from kidney and trachea. Science 244 (1989) 1469-1472
15. Redhead C.R., Edelman A.E., Brown D., Landry D.W., and al-Awqati Q. A ubiquitous 64-kDa protein is a component of a chloride channel of plasma and intracellular membranes. Proc. Natl. Acad. Sci. USA 89 (1992) 3716-3720
16. Landry D., Sullivan S., Nicolaides M., Redhead C., Edelman A., Field M., et al. Molecular cloning and characterization of p64, a chloride channel protein from kidney microsomes. J. Biol. Chem. 268 (1993) 14948-14955
17. Edwards J.C., Tulk B., and Schlesinger P.H. Functional expression of p64, an intracellular chloride channel protein. J. Membr. Biol. 163 (1998) 119-127
18. Qian Z., Okuhara D., Abe M.K., and Rosner M.R. Molecular cloning and characterization of a mitogen-activated protein kinase-associated intracellular chloride channel. J. Biol. Chem. 274 (1999) 1621-1627
19. Duncan R.R., Westwood P.K., Boyd A., and Ashley R.H. Rat brain p64H1, expression of a new member of the p64 chloride channel protein family in endoplasmic reticulum. J. Biol. Chem. 272 (1997) 23880-23886
20. Proutski I., Karoulias N., and Ashley R.H. Overexpressed chloride intracellular channel protein CLIC4 (p64H1) is an essential component of novel plasma membrane anion channels. Biochem. Biophys. Res. Commun. 297 (2002) 317-322
21. Tulk B.M., Schlesinger P.H., Kapadia S.A., and Edwards J.C. CLIC-1 functions as a chloride channel when expressed and purified from bacteria. J. Biol. Chem. 275 (2000) 26986-26993
22. Warton K., Tonini R., Fairlie W.D., Matthews J.M., Valenzuela S.M., Qiu M.R., et al. Recombinant CLIC1 (NCC27) assembles in lipid bilayers via a pH-dependent two-state process to form chloride ion channels with identical characteristics to those observed in Chinese hamster ovary cells expressing CLIC1. J. Biol. Chem. 277 (2002) 26003-26011
23. Tulk B.M., Kapadia S., and Edwards J.C. CLIC1 inserts from the aqueous phase into phospholipid membranes, where it functions as an anion channel. Am. J. Physiol. Cell Physiol. 282 (2002) C1103-C1112
24. Nishizawa T., Nagao T., Iwatsubo T., Forte J.G., and Urushidani T. Molecular cloning and characterization of a novel chloride intracellular channel-related protein, parchorin, expressed in water-secreting cells. J. Biol. Chem. 275 (2000) 11164-11173
25. Singh H., and Ashley R.H. Redox regulation of CLIC1 by cysteine residues associated with the putative channel pore. Biophys. J. 90 (2005) 1628-1638
26. Berryman M., and Bretscher A. Identification of a novel member of the chloride intracellular channel gene family (CLIC5) that associates with the actin cytoskeleton of placental microvilli. Mol. Biol. Cell 11 (2000) 1509-1521
27. Suginta W., Karoulias N., Aitken A., and Ashley R.H. Chloride intracellular channel protein CLIC4 (p64H1) binds directly to brain dynamin I in a complex containing actin, tubulin and 14-3-3 isoforms. Biochem. J. 359 (2001) 55-64
28. Berryman M., Bruno J., Price J., and Edwards J.C. CLIC-5A functions as a chloride channel in vitro and associates with the cortical actin cytoskeleton in vitro and in vivo. J. Biol. Chem. 279 (2004) 34794-34801
29. Dutzler R., Campbell E.B., Cadene M., Chait B.T., and MacKinnon R. X-ray structure of a ClC chloride channel at 3.0 Å reveals the molecular basis of anion selectivity. Nature 415 (2002) 287-294
30. Buechner M., Hall D.H., Bhatt H., and Hedgecock E.M. Cystic canal mutants in Caenorhabditis elegans are defective in the apical membrane domain of the renal (excretory) cell. Dev. Biol. 214 (1999) 227-241
31. Buechner M. Tubes and the single C. elegans excretory cell. Trends Cell Biol. 12 (2002) 479-484
32. Harrop S.J., DeMaere M.Z., Fairlie W.D., Reztsova T., Valenzuela S.M., Mazzanti M., et al. Crystal structure of a soluble form of the intracellular chloride ion channel CLIC1 (NCC27) at 1.4-Å resolution. J. Biol. Chem. 276 (2001) 44993-45000
33. Board P.G., Coggan M., Chelvanayagam G., Easteal S., Jermiin L.S., Schulte G.K., et al. Identification, characterization, and crystal structure of the Omega class glutathione transferases. J. Biol. Chem. 275 (2000) 24798-24806
34. 2+ release channels. Int. J. Biochem. Cell Biol. 36 (2004) 1599-1612
35. Redhead C., Sullivan S.K., Koseki C., Fujiwara K., and Edwards J.C. Subcellular distribution and targeting of the intracellular chloride channel p64. Mol. Biol. Cell 8 (1997) 691-704
36. Nilsson I., Saaf A., Whitley P., Gafvelin G., Waller C., and von Heijne G. Proline-induced disruption of a transmembrane alpha-helix in its natural environment. J. Mol. Biol. 284 (1998) 1165-1175
37. Littler D.R., Harrop S.J., Fairlie W.D., Brown L.J., Pankhurst G.J., Pankhurst S., et al. The intracellular chloride ion channel protein CLIC1 undergoes a redox-controlled structural transition. J. Biol. Chem. 279 (2004) 9298-9305
38. Fernandes A.P., and Holmgren A. Glutaredoxins: Glutathione-dependent redox enzymes with functions far beyond a simple thioredoxin backup system. Antioxid. Redox. Signal. 6 (2004) 63-74
39. Littler D.R., Assaad N.N., Harrop S.J., Brown L.J., Pankhurst G.J., Luciani P., et al. Crystal structure of the soluble form of the redox-regulated chloride ion channel protein CLIC4. Febs. J. 272 (2005) 4996-5007
40. Schinzel A., Kaufmann T., and Borner C. Bcl-2 family members: Integrators of survival and death signals in physiology and pathology [corrected]. Biochim. Biophys. Acta 1644 (2004) 95-105
41. Ashley R.H. Challenging accepted ion channel biology: p64 and the CLIC family of putative intracellular anion channel proteins (Review). Mol. Membr. Biol. 20 (2003) 1-11
42. Wilce M.C., and Parker M.W. Structure and function of glutathione S-transferases. Biochim. Biophys. Acta 1205 (1994) 1-18
43. Armstrong R.N. Structure, catalytic mechanism, and evolution of the glutathione transferases. Chem. Res. Toxicol. 10 (1997) 2-18
44. Board P.G., Coggan M., Wilce M.C., and Parker M.W. Evidence for an essential serine residue in the active site of the Theta class glutathione transferases. Biochem. J. 311 (1995) 247-250
45. Agianian B., Tucker P.A., Schouten A., Leonard K., Bullard B., and Gros P. Structure of a Drosophila sigma class glutathione S-transferase reveals a novel active site topography suited for lipid peroxidation products. J. Mol. Biol. 326 (2003) 151-165
46. Cromer B.A., Morton C.J., Board P.G., and Parker M.W. From glutathione transferase to pore in a CLIC. Eur. Biophys. J. 31 (2002) 356-364
47. Parker M.W., and Feil S.C. Pore-forming protein toxins: From structure to function. Prog. Biophys. Mol. Biol. 88 (2005) 91-142
48. Kourie J.I., and Wood H.B. Biophysical and molecular properties of annexin-formed channels. Prog. Biophys. Mol. Biol. 73 (2000) 91-134
49. Notredame C., Higgins D.G., and Heringa J. T-Coffee: A novel method for fast and accurate multiple sequence alignment. J. Mol. Biol. 302 (2000) 205-217
50. Felsenstein J. PHYLIP-phylogeny inference package (Version 3.2). Cladistics 5 (1989) 164-166
51. Jones D.T., Taylor W.R., and Thornton J.M. The rapid generation of mutation data matrices from protein sequences. Comput. Appl. Biosci. 8 (1992) 275-282
52. Page R.D. TreeView: An application to display phylogenetic trees on personal computers. Comput. Appl. Biosci. 12 (1996) 357-358
53. Hobert O. PCR fusion-based approach to create reporter gene constructs for expression analysis in transgenic C. elegans. Biotechniques 32 (2002) 728-730
54. Paul S.M., and Beitel G.J. Developmental biology. Tubulogenesis CLICs into place. Science 302 (2003) 2077-2078
55. Kostich M., Fire A., and Fambrough D.M. Identification and molecular-genetic characterization of a LAMP/CD68-like protein from Caenorhabditis elegans. J. Cell Sci. 113 (2000) 2595-2606
56. Treusch S., Knuth S., Slaugenhaupt S.A., Goldin E., Grant B.D., and Fares H. Caenorhabditis elegans functional orthologue of human protein h-mucolipin-1 is required for lysosome biogenesis. Proc. Natl. Acad. Sci. USA 101 (2004) 4483-4488