A 29 kDa intracellular chloride channel p64H1 is associated with large dense-core vesicles in rat hippocampal neurons

Journal of Neuroscience

Volumn 19, Issue 8, 1999, Pages 2919-2928

  Chuang, Jen Zen ^a   Milner, Teresa A ^b   Zhu, Meicai ^a   Sung, Ching Hwa ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b Division of Neurobiology   (United States)

Author keywords

Hippocampus; Intracellular chloride channel; Large dense core vesicle; Microtubules; NCC27; Neuropeptide; p64; p64H1

Indexed keywords

CHLORIDE CHANNEL; PROTON PUMP;

ANIMAL CELL; ARTICLE; COATED VESICLE; EXOCYTOSIS; HIPPOCAMPUS; IMMUNOELECTRON MICROSCOPY; LIMBIC SYSTEM; MICROTUBULE; MOLECULAR CLONING; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; RAT; RETROGRADE NERVE FIBER TRANSPORT;

EID: 0033561478     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-08-02919.1999     Document Type: Article

References (49)

1. Al-Awqati Q (1986) Proton-translocating ATPascs. Annu Rev Cell Biol 2:179-199.
2. Al-Awqati Q (1995) Chloride channels of intracellular organcllcs. Curr Opin Cell Biol 7:504-508.
3. Annaert WG, Quatacker J, Llona I, De Potter WP (1994a) Differences in the distribution of cytochromc h561 and synaptophysin in dog splenic nerve: a biochemical and immunocytochcmical study. J Ncurochem 62:265-274.
4. Bac H, Verkman AS (1990) Protc-in kinase A regulates chloride conductance in endocytic vesicles from proximal tubule. Nature 348:637-639.
5. Barasch J, Gershon MD, Nunez EA, Tamir H, Al-Awqati Q (1988) Thyrotropin induces the acidification of the secretory granules of parafollicular cells by increasing the chloride conductance of the granular membrane. J Cell Biol 107:2137-2147.
6. Bcrwin B, Floor E, Martin TF (1998) CAPS (mammalian UNC-31) protein localizes to membranes involved in dense-core vesicle exocytosis. Neuron 21:137-145.
7. Bradbury NA, Bridges RJ (1994) Role of membrane trafficking in plasma membrane solute transport. Am J Physiol 267:C1-C24.
8. Bulloch K, Prasad A, Conrad CD, McEwen BS, Milner TA (1996) Calcitonin gene-related peptidc level in the rat dentate gyrus increases after damage. NeuroReport 7:1036-1040.
9. Burgess TL, Kelly RB (1987) Constitutive and regulated secretion of proteins. Annu Rev Cell Biol 3:243-293.
10. Chan J, Aoki C, Pickel VM (1990) Optimization of differential immunogold-silver and peroxidase labeling with maintenance of ultrastructure in brain sections before plastic embedding. J Neurosci Methods 33:113-127.
11. Chuang J-Z, Sung C-H (1998) The cytoplasmic tail of rhodopsin acts as a novel apical sorting signal in polarized MDCK cells. J Cell Biol 142:1245-1256.
12. Chuang J-Z, Lin D, Lin S (1995) Molecular cloning, expression, and mapping of the high affinity actin-capping domain of chicken cardiac tensin. J Cell Biol 128:1095-1109.
13. Coyle JT, Kuhar MJ (1974) Subcellular localization of dopamine β-hydroxylase and endogenous norepinephrine in the rat hypothalamus. Brain Res 65:475-487.
14. Dartsch H, Kleene R, Kern HF (1998) In vitro condensation sorting of enzyme proteins isolated from rat pancreatic acinar cells. Eur J Cell Biol 75:211-222.
15. Dayanithi G, Nordmann JJ (1989) Chloride and magnesium dependence of vasopressin release from rat permeahilized neurohypophysial nerve endings. Neurosci Lett 106:305-309.
16. De Camilli P, Jahn R (1990) Pathways to regulated exocytosis in neurons. Annu Rev Physiol 52:625-645
17. Duncan RR, Weslwood PK, Boyd A, Ashley RH (1997) Rat brain p64H1. expression of a new member of the p64 chloride channel protein family in endoplasmic reticulum. J Biol Chem 272:23880-23886.
18. Edwards JC, Tulk B, Schlesinger PH (1998) Functional expression of p64, an intracellular chloride channel protein. J Membr Biol 163:119-127.
19. +-ATPase, a universal proton pump of cukaryotes. Biochem J 324:697-712.
20. Gainer H, Russell JT, Loh YP (1985) The enzymology and intracellular organization of peptide precursor processing: the secretory vesicle hypothesis. Neuroendocrinology 40:171-184.
21. Gerdes HH, Rosa P, Phillips E, Baeuerle PA, Frank R, Argos P, Huttner WB (1989) The primary structure of human secretogranin II, a widespread tyrosinc-sulfated secretory granule protein that exhibits low pH-and calcium-induced aggregation. J Biol Chem 264:12009-12015.
22. + pump in parallel to a chloride conductance. J Cell Biol 97:1303-1308.
23. Hsu SM, Raine L, Fanger H (1981) Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: comparison between ABC and unlabeled antibody (PAP) procedures. J Histochem Cytochem 29:577-580.
24. Hunter T (1982) Synthetic peptide substrates for a tyrosine protein kinase. J Biol Chem 257:4843-4848.
25. Huttner WB, Schiebler W, Greengard P, De Camilli P (1983) Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation. J Cell Biol 96:1374-1388.
26. Jahn R, Schiebler W, Ouimet C, Greengard P (1985) A 38,000-dalton membrane protein (p38) present in synaptic vesicles. Proc Natl Acad Sci USA 82:4137-4141.
27. Kozak M (1991) An analysis of vertebrate mRNA sequences: intimations of translational control. J Cell Biol 115:887-903.
28. Landry D, Sullivan S, Nicolaides M, Redhead C, Edelman A, Field M, Al-Awqati Q, Edwards J (1993) Molecular cloning and characterization of p64. a chloride channel protein from kidney microsomes. J Biol Chem 268:14948-14955.
29. Loh YP, Brownstein MJ, Gainer H (1984) Proteolysis in neuropeptide processing and other neural functions. Annu Rev Neurosci 7:189-222.
30. Milner TA, Veznedaroglu E (1992) Ultrastructural localization of neuropeptide Y-like immunoreactivity in the rat hippocampal formation. Hippocampus 2:107-125.
31. Mulberg AE, Tulk BM, Forgac M (1991) Modulation of coated vesicle chloride channel activity and acidification by reversible protein kinase A-dependent phosphorylation. J Biol Chem 266:20590-20593.
32. Patschinsky T, Hunter T, Esch FS, Cooper JA, Sefton BM (1982) Analysis of the sequence of amino acids surrounding sites of tyrosine phosphorylation. Proc Natl Acad Sci USA 79:973-977.
33. Peters A, Palay SL, Wehster HD (1991) The fine structure of the nervous system, 3rd ed. New York: Oxford UP.
34. Quatacker JR, Annaert WG, Miserez BJ, De Potter WP (1992) Immunocytochemical demonstration of dopamine-β-hydroxylase and cytochrome B561 on the axonal reticulum in bovine sympathetic neurons. J Histochem Cytochem 40:1599-1604.
35. Redhead CR, Edelman AE, Brown D, Landry DW, Al-Awqati Q (1992) A ubiquitous 64-kDa protein is a component of a chloride channel of plasma and intracellular membranes. Proc Natl Acad Sci USA 89:3716-3720.
36. Rogner UC, Heiss NS, Kioschis P, Wiemann S, Korn B, Poustka A (1996) Transcriptional analysis of the candidate region for incontinentia pigmenti (IP2) in Xq28. Genome Res 6:922-934.
37. + pumping into intracellular organelles. Annu Rev Physiol 48:403-413.
38. Simon DB, Karet FE, Hamdan JM, DiPietro A, Sanjad SA, Lifton RP (1996) Banter's syndrome, hypokalaemic alkalosiswith hypercalciuria, is caused by mutations in the Na-K-2Cl cotransporter NKCC2. Nat Genet 13:183-188.
39. Simon DB, Bindra RS, Mansfield TA, Nelson-Williams C, Mendonca E, Stone R, Schurman S, Nayir A, Alpay H, Bakkaloglu A, Rodriguez-Soriano J, Morales JM, Sanjad SA, Taylor CM, Pilz D, Brem A, Trachtman H, Griswold W, Richard GA, John E, Lifton RP (1997) Mutations in the chloride channel gene, CLCNKB, cause Bartter's syndrome type III. Nat Genet 17:171-178.
40. Sung CH, Schneider BG, Agarwal N, Papermaster DS, Nathans J (1991) Functional heterogeneity of mutant rhodopsins responsible for autosomal dominant retinitis pigmentosa. Proc Natl Acad Sci USA 88:8840-8844.
41. Thakker RV (1997) Chloride channels cough up. Nat Genet 17:125-127.
42. Thureson-Klein AK, Klein RL (1990) Exocytosis from neuronal large dense-cored vesicles. Int Rev Cytol 121:67-126.
43. Tooze J, Burke B (1987) Accumulation of adrenocorticotropin secretory granules in the midbody of telophase AtT20 cells: evidence that secretory granules move anterogradely along microtubules. J Cell Biol 104:1047-1057.
44. Tooze SA, Stinchcombe JC (1992) Biogenesis of secretory granules. Semin Cell Biol 3:357-366.
45. - channel p64, is expressed in brush border of renal proximal tubule. Am J Physiol 43:F1140-F1149.
46. Valenzuela SM, Martin DK, Por SB, Robbins JM, Wartom K, Bootcov MR, Schofield PR, Campbell TJ, Breit SN (1997) Molecular cloning and expression of a chloride ion channel of cell nuclei. J Biol Chem 272:12575-12582.
47. Veznedaroglu E, Milner TA (1992) Elimination of artifactual labeling of hippocampal mossy fibers seen following pre-embedding immunogold-silver technique by pretreatment with zinc chelator. Microsc Res Tech 23:100-101.
48. Winkler H (1997) Membrane composition of adrenergic large and small dense-cored vesicles and of synaptic vesicles: consequences for their biogenesis. Neurochem Res 22:921-932.
49. 2+-activated ATP hydrolysis. J Biol Chem 263:9859-9867.