A chimeric human-cat Fcγ-Fel d1 fusion protein inhibits systemic, pulmonary, and cutaneous allergic reactivity to intratracheal challenge in mice sensitized to Fel d1, the major cat allergen

Clinical Immunology

Volumn 120, Issue 1, 2006, Pages 45-56

  Terada, Tetsuya ^a   Zhang, Ke ^b   Belperio, John ^c   Londhe, Vedang ^c   Saxon, Andrew ^b  

^a OSAKA MEDICAL COLLEGE   (Japan)

^b Division of Clinical Immunology/Allergy   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Allergen immunotherapy; Allergen IgG chimeric protein; Allergy therapy; Cat allergy treatment; Fc gamma receptors; Rodent allergic reactions; Rush Immunotherapy

Indexed keywords

ALLERGEN; FC GAMMA FEL D1 FUSION PROTEIN; FEL D1 ALLERGEN; HYBRID PROTEIN; IMMUNOGLOBULIN E; IMMUNOGLOBULIN FC FRAGMENT; IMMUNOGLOBULIN G1; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ALLERGIC REACTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; CAT; CHIMERA; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; HYBRID; IMMUNOTHERAPY; IN VIVO STUDY; MALE; MEDIATOR RELEASE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROVOCATION TEST; SENSITIZATION; SIGNAL TRANSDUCTION; SKIN ALLERGY; SYSTEMIC DISEASE; TREATMENT OUTCOME;

ANIMALS; BRONCHIAL PROVOCATION TESTS; BRONCHOALVEOLAR LAVAGE FLUID; CATS; CELL COUNT; GLYCOPROTEINS; HISTOCYTOCHEMISTRY; HUMANS; HYPERSENSITIVITY, IMMEDIATE; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOTHERAPY; LUNG; MALE; MICE; MICE, INBRED BALB C; RECEPTORS, IGG; RECOMBINANT FUSION PROTEINS; SKIN; SPECIFIC PATHOGEN-FREE ORGANISMS;

EID: 33745117302     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2005.12.010     Document Type: Article

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