Differential effects of olmesartan and ramipril on inflammatory response after myocardial infarction in rats

Blood Pressure

Volumn 15, Issue 2, 2006, Pages 116-128

  Sandmann, Steffen ^a   Li, Jun ^a   Fritzenkötter, Carolin ^b   Spormann, Johannes ^b   Tiede, Karen ^b   Fischer, Jens W ^c   Unger, Thomas ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^c HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Angiotensin receptors; Inflammatory response; Myocardial infarction; Olmesartan; Ramipril

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; OLMESARTAN; PLACEBO; RAMIPRIL; TUMOR NECROSIS FACTOR ALPHA;

ACUTE HEART INFARCTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY INTIMA PROLIFERATION; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; DRUG DOSE REGIMEN; DRUG EFFECT; FEMORAL ARTERY; HEART CATHETERIZATION; HEART FUNCTION; HEART INFARCTION SIZE; HEART VENTRICLE REMODELING; MACROPHAGE; MALE; MYOCARDITIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; UPREGULATION;

ACUTE DISEASE; ANIMALS; ANTI-INFLAMMATORY AGENTS; CARDIOVASCULAR DISEASES; CARDIOVASCULAR SYSTEM; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; IMIDAZOLES; INFLAMMATION; INTERLEUKIN-1; INTERLEUKIN-6; MALE; MYOCARDIAL INFARCTION; PLACEBOS; RAMIPRIL; RATS; RATS, WISTAR; RENIN-ANGIOTENSIN SYSTEM; RNA, MESSENGER; TETRAZOLES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33745113499     PISSN: 08037051     EISSN: 16511999     Source Type: Journal    
DOI: 10.1080/08037050600586593     Document Type: Article

References (43)

1. Gurevitch, J. and Frolkis, I. and Yuhas, Y. and Lifschitz-Mercer, B. and Berger, E. and Paz, Y. and (1997) Anti-tumor necrosis factor-alpha improves myocardial recovery after ischemia and reperfusion. J Am Coll Cardiol, 30, pp. 1554-1561.
2. Irwin, M. W. and Mak, S. and Mann, D. L. and Qu, R. and Penninger, J. M. and Yan, A. and (1999) Tissue expression and immunolocalization of tumor necrosis factor-{alpha} in postinfarction dysfunctional myocardium. Circulation, 99, pp. 1492-1498.
3. Gwechenberger, M. and Mendoza, L. H. and Youker, K. A. and Frangoglannis, N. G. and Smith, C. W. and Michael, L. H. and (1999) Cardiac myocytes produce interleukin-6 in culture and in viable border zone of reperfused infarctions. Circulation, 99, pp. 546-551.
4. Kanda, T. and Kobayashi, I. and Nagai, R. and Entman, M. L. and Gwechenberger, M. and Youker, K. A. and (2000) Cardiac interleukin-6 in ischemic myocardium. Response. Circulation, 101, pp. E86.
5. Nian, M. and Lee, P. and Khaper, N. and Liu, P. (2004) Inflammatory cytokines and postmyocardial infarction remodeling. Circ Res, 94, pp. 1543-1553.
6. Finkel, M. S. and Oddis, C. V. and Jacob, T. D. and Walkins, S. C. and Hattler, B. G. and Simmons, R. L. (1992) Negative inotropic effects of cytokines on the heart mediated by nitric oxide. Science, 257, pp. 387-389.
7. Kinugawa, K. and Takahashi, T. and Kohmoto, O. and Yao, A. and Aoyagl, T. and Moniomura, S. and (1994) Nitric oxide-mediated effects of interleukin-6 on [Ca2+]i and cell contraction in cultured chick ventricular myocytes. Circ Res, 75, pp. 285-295.
8. De Gasparo, M. and Catt, K. J. and Inagami, T. and Wright, J. W. and Unger, T. (2000) International Union of Pharmacology. XXIII. The angiotensin II receptors. Pharmacol Rev, 52, pp. 415-472.
9. Stoll, M. and Unger, T. (2001) Angiotensin and its AT2 receptor: New insights into an old system. Regul Pept, 99, pp. 175-182.
10. Hirsch, A. T. and Talsness, C. E. and Schunkert, H. and Paul, M. and Dzau, V. J. (1991) Tissue-specific activation of cardiac angiotensin converting enzyme in experimental heart failure. Circ Res, 69, pp. 475-482.
11. Lindpaintner, K. and Lu, W. and Neidermajer, N. and Schieffer, B. and Just, H. and Ganten, D. and (1993) Selective activation of cardiac angiotensinogen gene expression in post-infarction ventricular remodeling in the rat. J Mol Cell Cardiol, 25, pp. 133-143.
12. Meggs, L. G. and Coupet, J. and Huang, H. and Cheng, W. and Ll, P. and Capasso, J. M. and (1993) Regulation of angiotensin II receptors on ventricular myocytes after myocardial infarction in rats. Circ Res, 72, pp. 1149-1162.
13. Nio, Y. and Matsubara, H. and Murasawa, S. and Kanasaki, M. and Inada, M. (1995) Regulation of gene transcription of angiotensin II receptor subtypes in myocardial infarction. J Clin Invest, 95, pp. 46-54.
14. Zhu, Y. Z. and Zhu, Y. C. and Li, J. and Schafer, H. and Schmidt, W. and Yao, T. and (2000) Effects of losartan on haemodynamic parameters and angiotensin receptor mRNA levels in rat heart after myocardial infarction. J Renin Angiotensin Aldosterone Syst, 1, pp. 257-262.
15. Schieffer, B. and Wirger, A. and Meybrunn, M. and Seitz, S. and Holtz, J. and Riede, U. N. and (1994) Comparative effects of chronic angiotensin-converting enzyme inhibition and angiotensin II type 1 receptor blockade on cardiac remodeling after myocardial infarction in the rat. Circulation, 89, pp. 2273-2282.
16. Schieffer, B. and Bünte, C. and Witte, J. and Hoeper, K. and Boger, R. H. and Schwedhelm, E. and (2004) Comparative effects of AT1-antagonism and angiotensin-converting enzyme inhibition on markers of inflammation and platelet aggregation in patients with coronary artery disease. J Am Coll Cardiol, 44, pp. 362-368.
17. Usui, M. and Egashira, K. and Tomita, H. and Koyanagl, M. and Katoh, M. and Shlmokawa, H. and (2000) Important role of local angiotensin II activity mediated via type 1 receptor in the pathogenesis of cardiovascular inflammatory changes induced by chronic blockade of nitric oxide synthesis in rats. Circulation, 101, pp. 305-310.
18. Fliser, D. and Buchholz, K. and Haller, H. (2004) Antiinflammatory effects of angiotensin II subtype 1 receptor blockade in hypertensive patients with microinflammation. Circulation, 110, pp. 1103-1107.
19. Campbell, D. J. and Kladis, A. and Duncan, A. M. (1994) Effects of converting enzyme inhibitors on angiotensin and bradykinin peptides. Hypertension, 23, pp. 439-449.
20. Blais, C., Jr. and Drapeau, G. and Raymond, P. and Lamontagne, D. and Gervais, N. and Venneman, I. and (1997) Contribution of angiotensin-converting enzyme to the cardiac metabolism of bradykinin: An interspecies study. Am J Physiol, 273, pp. H2263-H2271.
21. Linz, W. and Wiemer, G. and Gohlke, P. and Unger, T. (1995) Contribution of kinins to the cardiovascular actions of angiotensin-converting enzyme inhibitors. Pharmacol Rev, 47, pp. 25-49.
22. 3 - symporter in the rat heart after myocardial infarction. J Am Coll Cardiol, 37, pp. 2154-2165.
23. Sandmann, S. and Min, J. Y. and Meissner, A. and Unger, T. (1999) Effects of the calcium channel antagonist mibefradil on haemodynamic parameters and myocardial Ca(2+)-handling in infarct-induced heart failure in rats. Cardiovasc Res, 44, pp. 67-80.
24. Sandmann, S. and Bohle, R. M. and Dreyer, T. and Unger, T. (2000) The T-type calcium channel blocker mibefradil reduced interstitial and perivascular fibrosis and improved hemodynamic parameters in myocardial infarction-induced cardiac failure in rats. Virchows Arch, 436, pp. 147-157.
25. Sandmann, S. and Spormann, J. and Prenzel, F. and Shaw, L. and Unger, T. (2002) Calcium channel blockade limits transcriptional, translational and functional up-regulation of the cardiac calpain system after myocardial infarction. Eur J Pharmacol, 453, pp. 99-109.
26. Busche, S. and Gallinat, S. and Bohle, R. M. and Reinecke, A. and Seebeck, J. and Franke, F. and (2000) Expression of angiotensin AT(1) and AT(2) receptors in adult rat cardiomyocytes after myocardial infarction. A single-cell reverse transcriptase-polymerase chain reaction study. Am J Pathol, 157, pp. 605-611.
27. Li, J. and Kaschina, E. and Elkhrbash, K. and Timm, M. and Sommerfeld, M. and Unger, T. (2004) Angiotensin AT1 receptors are upregulated mainly in cardiomyocytes in the border-zones of myocardial infarction and mediate apoptosis in rats. Hypertension, 44, pp. 584 (abstract).
28. Sano, M. and Fukuda, K. and Kodama, H. and Pan, J. and Salto, M. and Malsuzakl, J. and (2000) Interleukin-6 family of cytokines mediate angiotensin II-induced cardiac hypertrophy in rodent cardiomyocytes. J Biol Chem, 275, pp. 29717-29723.
29. Schieffer, B. and Schieffer, E. and Hilfiker- Kleiner, D. and Hilliker, A. and Kovanen, P. T. and Kaartinen, M. and (2000) Expression of angiotensin II and interleukin 6 in human coronary atherosclerotic plaques: Potential implications for inflammation and plaque instability. Circulation, 101, pp. 1372-1378.
30. Fuchs, M. and Hilfiker, A. and Kaminski, K. and Hilfiker-Kleiner, D. and Guener, Z. and Klein, G. and (2003) Role of interleukin-6 for LV remodeling and survival after experimental myocardial infarction. FASEB J, 17, pp. 2118-2120.
31. Youker, K. and Smith, C. W. and Anderson, D. C. and Miller, D. and Michael, L. H. and Rossen, R. D. and (1992) Neutrophil adherence to isolated adult cardiac myocytes. Induction by cardiac lymph collected during ischemia and reperfusion. J Clin Invest, 89, pp. 602-609.
32. Kukielka, G. L. and Smith, C. W. and Manning, A. M. and Youker, K. A. and Michael, L. H. and Entman, M. L. (1995) Induction of interleukin-6 synthesis in the myocardium: Potential role in postreperfusion inflammatory injury. Circulation, 92, pp. 1866-1875.
33. Entman, M. L. and Youker, K. and Shoji, T. and Kukielka, G. and Shappell, S. B. and Taylor, A. A. and (1992) Neutrophil induced oxidative injury of cardiac myocytes. A compartmented system requiring CD11b/CD18-ICAM- 1 adherence. J Clin Invest, 90, pp. 1335-1345.
34. Finkel, M. S. and Hoffman, R. A. and Shen, L. and Oddis, C. V. and Simmons, R. L. and Hattler, B. G. (1993) Interleukin-6 (IL-6) as a mediator of stunned myocardium. Am J Cardiol, 71, pp. 1231-1232.
35. Yu, X. and Kennedy, R. H. and Liu, S. J. (2003) JAK2/STAT3, not ERK1/2, mediates interleukin- 6- induced activation of inducible nitric-oxide synthase and decrease in contractility of adult ventricular myocytes. J Biol Chem, 278, pp. 16304-16309.
36. Pan, Z. K. and Zuraw, B. L. and Lung, C. C. and Prossnitz, E. R. and Browning, D. D. (1996) Bradykinin stimulates NF-kappaB activation and interleukin 1beta gene expression in cultured human fibroblasts. J Clin Invest, 98, pp. 2042-2049.
37. Pan, J. and Fukuda, K. and Saito, M. and Matsuzaki, J. and Kodama, H. and Sano, M. and (1999) Mechanical stretch activates the JAK/STAT pathway in rat cardiomyocytes. Circ Res, 84, pp. 1127-1136.
38. Wu, L. and Iwai, M. and Nakagami, H. and Li, Z. and Chen, R. and Suzuki, J. and (2001) Roles of angiotensin II type 2 receptor stimulation associated with selective angiotensin II type 1 receptor blockade with valsartan in the improvement of inflammation-induced vascular injury. Circulation, 104, pp. 2716-2721.
39. Ono, K. and Matsumori, A. and Shioi, T. and Furukawa, Y. and Sasayama, S. (1998) Cytokine gene expression after myocardial infarction in rat hearts: Possible implication in left ventricular remodeling. Circulation, 98, pp. 149-156.
40. Li, J. and Schwimmbeck, P. L. and Tschope, C. and Leschka, S. and Husmann, L. and Rutschow, S. and (2002) Collagen degradation in a murine myocarditis model: Relevance of matrix metalloproteinase in association with inflammatory induction. Cardiovasc Res, 56, pp. 235-247.
41. Suzuki, K. and Murtuza, B. and Smolenski, R. T. and Sammut, I. A. and Suzuki, N. and Kaneda, Y. and (2001) Overexpression of interleukin-1 receptor antagonist provides cardioprotection against ischemia-reperfusion injury associated with reduction in apoptosis. Circulation, 104, pp. I308-I313.
42. Thaik, C. M. and Calderone, A. and Takahashi, N. and Colucci, W. S. (1995) Interleukin-1 beta modulates the growth and phenotype of neonatal rat cardiac myocytes. J Clin Invest, 96, pp. 1093-1099.
43. Pfeffer, M. A. and McMurray, J. J. and Velazquez, E. J. and Rouleau, J. L. and Kober, L. and Maggloni, A. P. and (2003) Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both. N Engl J Med, 349, pp. 1893-1906.