Study on the bone marrow mesenchymal stem cells induced drug resistance in the U937 cells and its mechanism

Chinese Medical Journal

Volumn 119, Issue 11, 2006, Pages 905-910

  Lin, Yu Mei ^a   Zhang, Gui Zhen ^a   Leng, Zong Xiang ^a   Lu, Zhen Xia ^a   Bu, Li Sha ^a   Gao, Shen ^a   Yang, Shao Juan ^a  

^a CHINA JAPAN UNION HOSPITAL OF JILIN UNIVERSITY   (China)

Author keywords

cDNA microarray; Drug resistance; Gene expression; Mesenchymal stem cells; U937 cells

Indexed keywords

DAUNORUBICIN; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; PROTEIN BCL XL; TRYPAN BLUE;

APOPTOSIS; ARTICLE; CELL ADHESION; CELL CULTURE; CELL CYCLE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL FUNCTION; CELL GROWTH; CELL PROLIFERATION; CELL STRAIN U937; CELL SUSPENSION; CELL VIABILITY; CONTROLLED STUDY; DNA DETERMINATION; DNA MICROARRAY; DRUG RESISTANCE; FLOW CYTOMETRY; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL TRANSPLANTATION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIVITY ANALYSIS; UPREGULATION;

EID: 33745058409     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00029330-200606010-00005     Document Type: Article

References (20)

1. Gibson LF. Survival of B lineage leukemic cells: signals from the bone marrow microenvironment. Leuk Lymphoma 2002;43:19-27.
2. Matsunaga T, Takemoto N, Sato T, Takimoto R, Tanaka I, Fujimi A, et al. Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia. Nat Mad 2003;9:1158-1165.
3. Paraguassu-Braga FH, Borojevic R, Bouzas LF, Barcinski MA, Bonomo A. Bone marrow stroma inhibits proliferation and apoptosis in leukemic cells through gap junction-mediated cell communication. Cell Death Differ 2003;10:1101-1108.
4. Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, et al. Multilineage potential of adult human mesenchymal stem cells. Science 1999;284:143-147.
5. Mudry RE, Fortney JE, York T, Hall BM, Gibson LF. Stromal cells regulate survival of B-lineage leukemic cells during chemotherapy. Blood 2000;96:1926-1932.
6. Kim DH, Yoo KH, Choi KS, Choi J, Choi SY, Yang SE, et al. Gene expression profile of cytokine and growth factor during differentiation of bone marrow-derived mesenchymal stem cell. Cytokine 2005;31:119-126.
7. Majumdar MK, Thiede MA, Haynesworth SE, Bruder SP, Gerson SL. Human marrow-derived mesenchymal stem cells (MSCs) express hematopoieticcytokines and support long-term hematopoiesis when differentiated toward stromaland osteogenic lineages. J Hematother Stem Cell Res 2000;9:841-848.
8. Ueno H, Sakita-Ishikawa M, Morikawa Y, Nakano T, Kitamura T, Saito M. A stromal cell-derived membrane protein that supports hematopoietic stem cells. Nat Immunol 2003;4:457-463.
9. Zhang Y, Li CD, Jiang XX, Li HL, Tang PH, Mao N. Comparison of mesenchymal stem cells from human placenta and bone marrow. Chin Med J 2004;117:882-887.
10. Liang R, Huang GS, Chen XQ, Wang Z, Feng JL, Zhang WP, et al. Effects of human fibroblastoid stromal cell line on proliferation of HL-60 cells and expression of VEGF. J Exp Hematol (Chin) 2003;11:476-479.
11. Liang R, Huang GS, Wang Z, Feng GL, Guo Y, Yang GR. Effects of normal human fibroblastoid stromal cell line on proliferation of acute myeloid leukemia cell line U937. J Fourth Mil Med Univ (Chin) 2003;24:1560-1562.
12. Konopleva M, Konoplev S, Hu W, Zaritskey AY, Afanasiev BV, Andreeff M. Stromal cells prevent apoptosis of AML cells by up-regulation of anti-apoptoticproteins. Leukemia 2002;16:1713-1724.
13. Tabe Y, Konopleva M, Munsell MF, Marini FC, Zompetta C, McQueen T, et al. PML-RARalpha is associated with leptin-receptor induction: the role ofmesenchymal stem cell-derived adipocytes in APL cell survival. Blood 2004;103:1815-1822.
14. Lee C, Lin Y, Huang M, Lin C, Liu C, Chow J, et al. Increased cellular glutathione and protection by bone marrow stromal cells account for the resistance of non-acute promylocytic leukemia acute myeloid leukemia cells to arsenic trioxide in vivo. Leuk Lymphoma 2006;47:521-529.
15. Wang L, Fortney JE, Gibson LF. Stromal cell protection of B-lineage acute lymphoblastic leukemic cells during chemotherapy requires active Akt. Leuk Res 2004;28:733-742.
16. Sugiura N, Adams SM, Corriveau RA. An evolutionarily conserved N-terminal acetyltransferase complex associated withneuronal development. J Biol Chem 2003;278:40113-40120.
17. Yokota T, Matsuzaki Y, Miyazawa K, Zindy F, Roussel MF, Sakai T. Histone deacetylase inhibitors activate INK4d gene through Sp1 site in itspromoter. Oncogene 2004;23:5340-5349.
18. Chiba T, Yokosuka O, Fukai K, Kojima H, Tada M, Arai M, et al. Cell growth inhibition and gene expression induced by the histone deacetylaseinhibitor, trichostatin A, on human hepatoma cells. Oncology 2004;66:481-491.
19. Neben K, Tews B, Wrobel G, Hahn M, Kokocinski F, Giesecke C, et al. Gene expression patterns in acute myeloid leukemia correlate with centrosome aberrations and numerical chromosome changes. Oncogene 2004;23:2379-2384.
20. Yih LH, Hsueh SW, Luu WS, Chiu TH, Lee TC. Arsenite induces prominent mitotic arrest via inhibition of G2 checkpointactivation in CGL-2 cells. Carcinogenesis 2005;26:53-63.