M1 muscarinic receptors contribute to, whereas M4 receptors inhibit, dopamine D1 receptor-induced [3H]- cyclic AMP accumulation in rat striatal slices

Neurochemical Research

Volumn 31, Issue 4, 2006, Pages 555-561

  Sánchez Lemus, Enrique ^a   Arias Montaño, José Antonio ^a  

^a DEPARTAMENTO DE FÍSICA   (Mexico)

Author keywords

Basal ganglia; cAMP; D1 receptors; M1 receptors; Muscarinic receptors; Striatum

Indexed keywords

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; 2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; 6 CHLORO 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; ADENINE; CARBACHOL; CYCLIC AMP; DOPAMINE 1 RECEPTOR; DOPAMINE 1 RECEPTOR STIMULATING AGENT; ISOBUTYLMETHYLXANTHINE; MUSCARINIC AGENT; MUSCARINIC M1 RECEPTOR; MUSCARINIC M4 RECEPTOR; MUSCARINIC RECEPTOR BLOCKING AGENT; PROTEIN KINASE C INHIBITOR; TOXIN; ALKALOID; BENZAZEPINE DERIVATIVE; CHOLINERGIC RECEPTOR BLOCKING AGENT; CHOLINERGIC RECEPTOR STIMULATING AGENT; DOPAMINE RECEPTOR STIMULATING AGENT; FURAN DERIVATIVE; HIMBACINE; METHYLSCOPOLAMINE; NAPHTHALENE DERIVATIVE; PIPERIDINE DERIVATIVE; PIRENZEPINE; PROTEIN KINASE C; SK&F 81297;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN MEMBRANE; BRAIN SLICE; CONTROLLED STUDY; CORPUS STRIATUM; IC 50; LIGAND BINDING; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; ANIMAL; CYTOLOGY; DRUG ANTAGONISM; METABOLISM; RADIOASSAY; WISTAR RAT;

ALKALOIDS; ANIMALS; BENZAZEPINES; CARBACHOL; CHOLINERGIC AGONISTS; CORPUS STRIATUM; CYCLIC AMP; DOPAMINE AGONISTS; FURANS; MALE; MUSCARINIC ANTAGONISTS; N-METHYLSCOPOLAMINE; NAPHTHALENES; PARASYMPATHOLYTICS; PIPERIDINES; PIRENZEPINE; PROTEIN KINASE C; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTOR, MUSCARINIC M1; RECEPTOR, MUSCARINIC M4; RECEPTORS, DOPAMINE D1;

EID: 33745050843     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-006-9052-8     Document Type: Article

References (44)

1. Hoover DB, Muth EA, Jacobowitz DM (1978) A mapping of the distribution of acetycholine, choline acetyltransferase and acetylcholinesterase in discrete areas of rat brain. Brain Res 153:295-306
2. Gerfen CR, Wilson CJ (1996) The basal ganglia. In: Björklund A, Hökfelt T, Swanson L (eds) Handbook of chemical neuroanatomy, integrated systems of the CNS, Part III. Elsevier, Amsterdam, pp369-466
3. Tepper JM, Bolam JP (2004) Functional diversity and specificity of neostriatal interneurons. Curr Opin Neurobiol 14:685-692
4. Hauber W (1998) Involvement of basal ganglia transmitter systems in movement initiation. Prog Neurobiol 56:507-540
5. Caulfield MP, Birdsall NJM (1998) Classification of muscarinic acetylcholine receptors. Pharmacol Rev 50:279-290
6. Levey AI, Kitt CA, Simonds WF, Price DL, Brann MR (1991) Identification and localization of muscarinic acetylcholine receptor proteins in brain with subtype-specific antibodies. J Neurosci 11:3218-3226
7. Yasuda RP, Ciesla W, Flores LR, Wall SJ, Li M, Satkus SA, Weisstein JS, Spagnola BV, Wolfe BB (1993) Development of antisera selective for m4 and m5 muscarinic cholinergic receptors: distributions of m4 and m5 receptors in rat brain. Mol Pharmacol 43:149-157
8. Waelbroeck M, Tastenoy M, Camus J, Christophe J (1990) Binding of selective antagonists to four muscarinic receptors (M1 to M4) in rat forebrain. Mol Pharmacol 38:267-273
9. Pisani A, Bonsi P, Picconi B, Tolu M, Giacomini P, Scamati E (2001) Role of tonically-active neurons in the control of striatal function: cellular mechanisms and behavioral correlates. Prog Neuropsychopharmacol Biol Psychiatr 25:211-230
10. Clarke CE (2002) Medical management of Parkinson's disease. J Neurol Neurosurg Psychiatr 72(1):I22-I27
11. Hamani C, Lozano AM (2003) Physiology and pathophysiology of Parkinson's disease. Ann NY Acad Sci 991:15-21
12. 1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons. Neuron 14:385-397
13. Olianas MC, Adem A, Karlsson E, Onali P (1996) Rat striatal muscarinic receptors coupled to the inhibition of adenylyl cyclase activity: potent block by the selective m4 ligand muscarinic toxin 3 (MT3). Br J Pharmacol 118:283-288
14. Olianas MC, Onali P (1999) PD 102807, a novel muscarinic M4 receptor antagonist, discriminates between striatal and cortical muscarinic receptors coupled to cyclic AMP. Life Sci 65:2233-2240
15. 2+ and protein kinase C. Biochem Biophys Acta 1095:55-260
16. 4 muscarinic acetylcholine receptors. J Biol Chem 269:9767-9773
17. Gurwitz D, Haring R, Heldman E, Fraser CM, Manor D, Fisher A (1994) Discrete activation of transduction pathways associated with acetylcholine m1 receptor by several muscarinic ligands. Eur J Pharmacol 267:21-31
18. Burford NT, Nahorski SR (1996) Muscarinic m1 receptor-stimulated adenylate cyclase activity in chinese hamster ovary cells is mediated by Gsα and is not a consequence of phosphoinositidase C activation. Biochem J 315:883-888
19. Hersch SM, Gutekunst CA, Rees HD, Heilman CJ, Levey AI (1994) Distribution of m1-m4 muscarinic receptor proteins in the rat striatum: light and electron microscopic immunocytochemistry using subtype-specific antibodies. J Neurosci 14:3351-3363
20. 3 receptors in rat striatum: a binding study. Arch Med Res 28:493-497
21. Alexander SPH (1995) The measurement of cyclic AMP levels in biological preparations. In: Kendall DA, Hill SJ (eds) Signal transduction protocols. Humana Pres, Totowa, pp79-89
22. Cheng YC, Prusoff WH (1973) Relationship between the inhibition constant (Ki) and the concentration of inhibitor which causes 50 percent inhibition (IC50) of an enzymatic reaction. Biochem Pharmacol 22:3099-3108
23. 1 receptor-induced cAMP accumulation in rat striatal slices. Neurosci Lett 364:179-184
24. Adem A, Karlsson E (1997) Muscarinic receptor subtype selective toxins. Life Sci 60:1069-1076
25. Onali P, Adem A, Karlsson E, Olianas MC (2005) The pharmacological action of MT-7. Life Sci 76:1547-1552
26. 3 muscarinic receptors. Neurosci Lett 233:69-72
27. Berridge M, Lipp P, Bootman MD (2000) The versatility and universality of calcium signalling. Nat Rev Mol Cell Biol 1:11-21
28. Sunahara RK, Dessauer CW, Gilman AG (1996) Complexity and diversity of mammalian adenylyl cyclases. Annu Rev Pharmacol Toxicol 36:461-480
29. Yan Z, Flores-Hernández J, Surmeier DJ (2001) Coordinated expression of muscarinic receptor messenger RNAs in striatal medium spiny neurons. Neuroscience 103:1017-1024
30. Santiago MP, Potter LT (2001) Biotinylated m4-toxin demonstrates more M4 muscarinic receptor protein on direct than indirect striatal projection neurons. Brain Res 894:12-20
31. Figueroa A, Galarraga E, Bargas J (2002) Muscarinic receptors involved in the subthreshold cholinergic actions of neostriatal spiny neurons. Synapse 46:215-223
32. Potter LT, Flynn DD (2004) Liang JS, McCollum MH. Studies of muscarinic neurotransmission with antimuscarinic toxins. Prog Brain Res 145:121-128
33. 2+ channels. J Neurophysiol 93:2507-2519
34. 1 receptor stimulation: involvement of enhanced nitric oxide production via neurokinin-2 receptor activation. Neuroscience 84:511-518
35. 3H]acetylcholine release in mouse striatum through multiple receptor subtypes. Neuroscience 95:367-376
36. Baumgold J, Fishman PH (1988) Muscarinic receptor-mediated increase in cAMP levels in SK-N-SH human neuroblastoma cells. Biochem Biophys Res Commun 154:1137-1143
37. Felder CC, Kanterman RY, Ma AL, Axelrod J (1989) A transfected m1 muscarinic acetylcholine receptor stimulates adenylate cyclase via phosphatidylinositol hydrolysis. J Biol Chem 264:20356-20362
38. 2+-inhibitable adenylyl cyclase in dopaminergically innervated rat brain regions. Mol Brain Res 22:236-244
39. 2+-sensitive adenylyl cyclases, key integrators of cellular signalling. Life Sci 62:1647-1652
40. Wilkinson SE, Parker PJ, Nixon JS (1993) Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C. Biochem J 294:335-337
41. Martiny-Baron G, Kazanietz MG, Mischak H, Blumberg PM, Kochs G, Hug H, Marme D, Schachtele C (1993) Selective inhibition of protein kinase C isoenzymes by the indolocarbazole Gö 6976. J Biol Chem 268:9194-9197
42. Bolam JP, Hanley JJ, Booth PAC, Bevan MD (2000) Synaptic organisation of the basal ganglia. J Anat 196:527-542
43. 4 muscarinic acetylcholine receptor knockout mice. Proc Natl Acad Sci USA 96:10483-10488
44. Salamone JD, Correa M, Carlson BB, Wisniecki A, Mayorga AJ, Nisenbaum E, Nisenbaum L, Felder C (2001) Neostriatal muscarinic receptor subtypes involved in the generation of tremulous jaw movements in rodents implications for cholinergic involvement in parkinsonism. Life Sci 68:2579-2584