Effect of oligomer procyanidins on reperfusion arrhythmias and lactate dehydrogenase release in the isolated rat heart

Arzneimittel-Forschung/Drug Research

Volumn 56, Issue 5, 2006, Pages 317-321

  Makdessi, Samar Al ^a,b   Sweidan, Hicham ^a   Jacob, Ruthard ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b Inst U   (Germany)

Author keywords

Antiarrhythmic drugs; Lactate dehydrogenase release; Langendorff perfused heart; Procyanidins, oligomer; Reperfusion arrhythmias; Ventricular fibrillation; Vitis vinifera

Indexed keywords

LACTATE DEHYDROGENASE; PROCYANIDIN DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRADYCARDIA; CONTROLLED STUDY; DRUG EFFECT; ELECTROCARDIOGRAM; ENZYME RELEASE; GRAPE; HEART ARRHYTHMIA; HEART ATRIUM FLUTTER; HEART FIBRILLATION; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE TACHYCARDIA; ISCHEMIA; MALE; NONHUMAN; RAT; REPERFUSION;

EID: 33745040540     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0031-1296728     Document Type: Article

References (25)

1. Jeroudi, M. O., Hartley, C. J., Bolli, R., Myocardial reperfusion injury: role of oxygen radicals and potential therapy with antioxidants. Am. J. Cardiol. 73, 2B (1994)
2. Ursini, F., Rapuzzi, I., Toniolo, R. et al., Characterization of antioxidant effect of procyanidins. Methods Enzymol. 335, 338 (2001)
3. Maffei Facino, R., Carini, M., Aldini, G. et al., Free radicals scavenging action and anti-enzyme activities of procyanidines from Vitis vinifera. A mechanism for their capillary protective actions. Arzneim.-Forsch./Drug Res. 44, 592 (1994)
4. Moini, H., Guo, Q., Packer L., Enzyme inhibition and protein-binding action of the procyanidin-rich french maritime pine bark extract, pycnogenol: effect on xanthine oxidase. J. Agric. Food Chem. 48, 5630 (2000)
5. Kim, S.H., Kang, K.W., Kim, K.W. et al., Procyanidins in crataegus extract evoke endothelium-dependent vasorelaxation in rat aorta. Life Sci. 67, 121 (2000)
6. Quettier-Deleu, C., Voiselle, G., Fruchart, J.C. et al., Hawthorn extracts inhibit LDL oxidation. Pharmazie 58, 577 (2003)
7. Al Makdessi, S., Sweidan, H., Müllner, S. et al., Myocardial protection by pretreatment with Crataegus oxyacantha. An assessment by means of the release of lactate dehydrogenase by the ischemic and reperfused Langendorff heart. Arzneim.-Forsch./Drug Res. 46, 25 (1996)
8. Al Makdessi, S., Sweidan, H., Dietz, K. et al., Protective effect of Crataegus oxyacantha against reperfusion arrhythmias after global no-flow ischemia. Basic Res. Cardiol. 94, 71 (1999)
9. Simonetti, P., Ciappellano, S., Gardana, C. et al., Procyanidins from Vitis vinifera seeds: in vivo effects on oxidative stress. J. Agric. Food Chem. 50, 6217 (2002)
10. Fitzpatrick, D. F., Bing, B., Maggi, D. A. et al., Vasodilating procyanidins derived from grape seeds. Ann. N. Y. Acad. Sci. 957, 78 (2002)
11. Aldini, G., Carini, M., Piccoli, A. et al., Procyanidins from grape seeds protect endothelial cells from peroxynitrite damage and enhance endothelium-dependent relaxation in human artery: new evidences for cardio-protection. Life Sci. 73, 2883 (2003)
12. Osakabe, N., Yasuda, A., Natsume, M. et al., Catechins and their oligomers linked by C4-C8 bonds are major cacao polyphenols and protect low-density lipoprotein from oxidation in vitro. Exp. Biol. Med. 227, 51 (2002)
13. Maffei Facino, R., Carini, M., Aldini, G. et al., Diet enriched with procyanidins enhances antioxidant activity and reduces myocardial post-ischaemic damage in rats. Life Sci. 64, 627 (1999)
14. Maffei Facino, R., Carini, M., Aldini, G. et al., Procyanidines from Vitis vinifera seeds protect rabbit heart from ischemia/reperfusion injury: antioxidant intervention and/or iron and copper sequestring ability. Planta Med. 62, 495 (1996)
15. Franz, M. R., Burkhoff, D., Spurgeon, H. et al., In vitro validation of a new catheter technique for recording monophasic action potentials. Eur. Heart J. 7, 34 (1986)
16. Isensee, H., Jacob, R., Differential effects of various oil diets on the risk of cardiac arrhythmias in rats. J. Cardiovasc. Risk 1, 353 (1994)
17. Gonthier, M. P., Donovan, J. L., Texier, O. et al., Metabolism of dietary procyanidins in rats. Free Radic. Biol. Med. 35, 837 (2003)
18. Rein, D., Lotito, S., Holt, R. R. et al., Epicatechin in human plasma: in vivo determination and effect of chocolate consumption on plasma oxidation status. J. Nutr. 130, 2109S (2000)
19. Müllner, S., Heinle, H., Meierkord., S. et al., Auswirkungen einer Vorbehandlung mit Crataegus oxyacantha auf Infarktzone, Lactatdehydrogenase- Spiegel und Arrhythmieinzidenz beim Langendorff-Präparat der Ratte. Z. Kardiol. 84 (Suppl. 1), 827 (1995)
20. Al Makdessi, S., Sweidan, H., Jacob, R., n-3 versus n-6 fatty acid incorporation into the phospholipids of rat heart sarcolemma. A comparative study of four oil diets. J. MoL. Cell Cardiol. 26, 23 (1994)
21. Fine, A. M., Oligomeric proanthocyanidin complexes: History, structure, and phytopharmaceutical applications. Altern. Med. Rev. 5, 144 (2000)
22. Moini, H., Rimbach, G., Packer, L., Molecular aspects of procyanidin biological activity: Disease preventative and therapeutic potentials. Drug Metabol. Drug Interact. 17, 237 (2000)
23. Actis-Goretta, L., Ottaviani, J. I., Keen, C. L. et al., Inhibition of angiotensin converting enzyme (ACE) activity by flavan-3-ols procyanidins. FEBS Lett.- 555, 597 (2003)
24. Joshi, S. S., Kuszynski, C. A., Bagchi, D., The cellular and molecular basis of health benefits of grape seed proanthocyanidin extract. Curr. Pharm. Bniotechnol. 2, 187 (2001)
25. Bagchi, D., Bagchi, M., Stohs, S. J., Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention. Toxicology 148, 187 (2000)