Structure-activity relationship of a series of diaminoalkyl substituted benzimidazole as neuropeptide Y Y1 receptor antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 5, 1999, Pages 647-652

  Zarrinmayeh, Hamideh ^a   Zimmerman, Dennis M ^a   Cantrell, Buddy E ^a   Schober, Douglas A ^a   Bruns, Robert F ^a   Gackenheimer, Susan L ^a   Ornstein, Paul L ^a   Hipskind, Philip A ^a   Britton, Thomas C ^a   Gehlert, Donald R ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZIMIDAZOLE DERIVATIVE; CYCLIC AMP; IODINE 125; NEUROPEPTIDE Y RECEPTOR ANTAGONIST; NEUROPEPTIDE Y1 RECEPTOR; PEPTIDE YY;

ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; NONHUMAN; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

ADENYLATE CYCLASE; ANIMALS; BENZIMIDAZOLES; CHO CELLS; CRICETINAE; HUMANS; NEUROPEPTIDES; RECEPTORS, NEUROPEPTIDE Y; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

ANIMALIA;

EID: 0033535385     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00082-7     Document Type: Article

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