Effects of methylmalonyl-CoA mutase gene knockouts on erythromycin production in carbohydrate-based and oil-based fermentations of Saccharopolyspora erythraea

Journal of Industrial Microbiology and Biotechnology

Volumn 33, Issue 7, 2006, Pages 600-609

  Reeves, Andrew R ^a   Brikun, Igor A ^a   Cernota, William H ^a   Leach, Benjamin I ^a   Gonzalez, Melissa C ^a   Weber, J Mark ^a  

^a Fermalogic Inc   (United States)

Author keywords

Erythromycin; Knockout; Methylmalonyl CoA mutase; Oil based fermentation; Saccharopolyspora erythraea; Strain improvement

Indexed keywords

CARBOHYDRATE; ERYTHROMYCIN; METHYLMALONYL COENZYME A MUTASE; OIL;

BACTERIAL GENE; BACTERIAL GENETICS; BACTERIAL STRAIN; CONFERENCE PAPER; CONTROLLED STUDY; DRUG SYNTHESIS; FERMENTATION; KNOCKOUT GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; SACCHAROPOLYSPORA; STREPTOMYCES ERYTHRAEUS; WILD TYPE;

BACTERIAL PROTEINS; CARBOHYDRATE METABOLISM; CARBOHYDRATES; CULTURE MEDIA; ERYTHROMYCIN; FERMENTATION; GENES, BACTERIAL; GENETIC ENGINEERING; INDUSTRIAL MICROBIOLOGY; METHYLMALONYL-COA MUTASE; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; MUTAGENESIS; MUTATION; OILS; PIGMENTATION; SACCHAROPOLYSPORA; SPORES, BACTERIAL;

SACCHAROPOLYSPORA ERYTHRAEA;

EID: 33745036968     PISSN: 13675435     EISSN: 14765535     Source Type: Journal    
DOI: 10.1007/s10295-006-0094-3     Document Type: Conference Paper

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