Solid-phase synthesis of PNA monomer by Ugi four-component condensation reaction

Chinese Chemical Letters

Volumn 16, Issue 5, 2005, Pages 585-588

  Wang, Wen Hao ^a   Zou, Xiao Min ^a   Zhang, Xin ^a   Fu, Yi Qiu ^a   Xu, Ping ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Isocyanide; Peptide nucleic acids (PNA); Solid phase synthesis; Ugi four component condensation reaction (U 4CR)

Indexed keywords

EID: 33745013919     PISSN: 10018417     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. P. E. Nielsen, M. Egholm, R. H. Berg, O. Buchardt, Science, 1991, 254, 1497.
2. (a) M. Egholm, O. Buchardt, L. Christensen, et al., Nature, 1993, 365, 556.
3. (b) P. Wittung, P. E. Nielsen, O. Buchardt, M. Egholm, B. NordeÂn, Nature, 1994, 368, 561.
4. (c) P.E. Nielsen, M. Egholm, O. Buchardt, Gene, 1994, 149, 139.
5. P. E. Nielsen, Curr. Opin. Biotechnol., 1999, 10, 71.
6. M. Egholm, O. Buchardt, P.E. Nielsen, R. H. Berg, J. Am. Chem. Soc., 1992, 114, 9677.
7. K. L. Dueholm, M. Egholm, C. Behrends, L. Christensen, H. F. Hansen, T. Vulpius, K. Petersen, R. H. Berg, P. E. Nielsen, O. Buchardt, J. Org. Chem., 1994, 59, 5767.
8. (a) B. Hyrup, M. Egholm, P.E. Nielsen, P. Wittung, B. Nordén, O. Buchardt, J. Am. Chem. Soc., 1994, 116, 7964.
9. (b) D.W. Will, G. Breipohl, D. Langner, J. Knolle, E. Uhlmann, Tetrahedron, 1995, 51(44), 12069.
10. (a) H. Gröger, M. Hatam, J. Kintscher, J. Martens, Synth. Commun., 1996, 26(18), 3383.
11. (b) A. Dömling, W. Richter, I. Ugi, Nucleosides & Nucleotides, 1997, 16(7-9), 1753.
12. (c) W. Maison, I. Schlemminger, O. Westerhoff, J. Martens, Bioorg. Med. Chem. Lett., 1999, 9(4), 581.
13. (d) W. Maison, I. Schlemminger, O. Westerhoff, J. Martens, Bioorg. Med. Chem., 2000, 8(6), 1343.
14. (e) A. Dömling, Nucleosides & Nucleotides, 1998, 17(9-11), 1667.
15. (f) A. Dömling, K-Z. Chi, M. Barrère, Bioorg. Med. Chem. Lett., 1999, 9(19), 2871.
16. A. Dömling, I. Ugi, Angew. Chem. Int. Ed. Engl., 2000, 39(18), 3168.
17. P. Xu, T. Zhang, W. Wang, X. Zou, X. Zhang, Y. Fu, Synthesis, 2003, 1171.
18. W. Wang, T. Zhang, P. Xu, J. Chinese Pharm. Sci., 2003, 12(2), 66.