Combinatorial generation of nucleobase libraries by MCR

Nucleosides and Nucleotides

Volumn 16, Issue 7-9, 1997, Pages 1753-1756

  Dömling, Alexander ^a   Richter, Wolfgang ^a   Ugi, Ivar ^b  

^a MORPHOCHEM Ges F K   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; ANTIVIRUS AGENT; NUCLEOSIDE;

ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; CONFERENCE PAPER; DRUG CONFORMATION; DRUG MIXTURE; DRUG SYNTHESIS; GENE LIBRARY; NUCLEOTIDE SEQUENCE; STRUCTURE ACTIVITY RELATION;

EID: 0030784522     PISSN: 07328311     EISSN: None     Source Type: Journal    
DOI: 10.1080/07328319708006270     Document Type: Conference Paper

References (7)

1. W.Lewis, M.C.Dalakas, Nature Medicine, 1, 417 (1995).
2. M.J.Kozal, Nature Medicine, 2, 755 (1996).
3. The possibility of generating large libraries of low molecular weight compounds was proposed the first time by one of us: I.Ugi, C.Steinbrückner, Chem. Ber., 94, 734 (1961). I.Ugi, A.Dömling, B.Gruber, M.Heilingbrunner, C.Heiß, W.Hörl, in: Softwareentwicklung in der Chemie (R.Moll, Ed.), Frankfurt: Gesellschaft Deutscher Chemiker, 1995, p. 113 (Volume of the GDCh-workschop 16.-18.11.1994.
4. The possibility of generating large libraries of low molecular weight compounds was proposed the first time by one of us: I.Ugi, C.Steinbrückner, Chem. Ber., 94, 734 (1961). I.Ugi, A.Dömling, B.Gruber, M.Heilingbrunner, C.Heiß, W.Hörl, in: Softwareentwicklung in der Chemie (R.Moll, Ed.), Frankfurt: Gesellschaft Deutscher Chemiker, 1995, p. 113 (Volume of the GDCh-workschop 16.-18.11.1994.
5. A.Dömling, W.Hörl, I.Ugi.,Endeavour, 18, 115 (1994).
6. G.Gokel, G.Lüdke, I.Ugi: "Four-Component Condensations and Realated Reactions " in: Isonitrile Chemistry, Ed. I.Ugi, Academic Press, New York, 1971.
7. A.Dömling, W.Richter unpublished results.