메뉴 건너뛰기




Volumn 47, Issue 3, 2006, Pages 124-132

Bone morphogenetic protein-2 counterregulates interleukin-18 mRNA and protein in MC3T3-E1 mouse osteoblastic cells

Author keywords

BMP 2; Caspase 1; FGF 2; IL 18; MC3T3 E1 cells; Mouse osteoblast

Indexed keywords

COMPLEMENTARY DNA; FIBROBLAST GROWTH FACTOR 2; INTERLEUKIN 18; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; MESSENGER RNA; OSTEOPROTEGERIN; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; RECOMBINANT FIBROBLAST GROWTH FACTOR; RNA;

EID: 33744974556     PISSN: 03008207     EISSN: 16078438     Source Type: Journal    
DOI: 10.1080/03008200600685350     Document Type: Article
Times cited : (13)

References (43)
  • 1
    • 0034284970 scopus 로고    scopus 로고
    • Bone resorption by osteoclasts
    • [CSA]
    • Teitelbaum, S. (2000) Bone resorption by osteoclasts Science, 289, pp. 1504-1508. [CSA]
    • (2000) Science , vol.289 , pp. 1504-1508
    • Teitelbaum, S.1
  • 2
    • 0034285013 scopus 로고    scopus 로고
    • The osteoblast: A sophisticated fibroblast under central surveillance
    • [CSA] [CROSSREF]
    • Ducy, P. and Schinke, T. and Karsenty, G. (2000) The osteoblast: A sophisticated fibroblast under central surveillance Science, 289, pp. 1501-1504. [CSA] [CROSSREF]
    • (2000) Science , vol.289 , pp. 1501-1504
    • Ducy, P.1    Schinke, T.2    Karsenty, G.3
  • 3
    • 34250019537 scopus 로고
    • Bone: Formation by autoinduction
    • [CSA]
    • Urist, M. (1965) Bone: Formation by autoinduction Science, 150, pp. 893-899. [CSA]
    • (1965) Science , vol.150 , pp. 893-899
    • Urist, M.1
  • 4
    • 0024893773 scopus 로고
    • Bone morphogenetic proteins
    • [CSA] [CROSSREF]
    • Wozney, J. (1989) Bone morphogenetic proteins Prog. Growth Factor Res., 1, pp. 267-280. [CSA] [CROSSREF]
    • (1989) Prog. Growth Factor Res. , vol.1 , pp. 267-280
    • Wozney, J.1
  • 5
    • 0031974284 scopus 로고    scopus 로고
    • Bone morphogenetic protein and bone morphogenetic protein gene family in bone formation and repair
    • [CSA]
    • Wozney, J. and Rosen, V. (1998) Bone morphogenetic protein and bone morphogenetic protein gene family in bone formation and repair Clin. Orthop., 346, pp. 26-37. [CSA]
    • (1998) Clin. Orthop. , vol.346 , pp. 26-37
    • Wozney, J.1    Rosen, V.2
  • 6
    • 0025857671 scopus 로고
    • Recombinant human bone morphogenetic protein-2 stimulates osteoblastic maturation and inhibits myogenic differentiation in vitro
    • [CSA] [CROSSREF]
    • Yamaguchi, A. and Katagiri, T. and Ikeda, T. and Wozney, J. and Rosen, V. and Wang, E. and Kahn, A. and Suda, T. and Yoshiki, S. (1991) Recombinant human bone morphogenetic protein-2 stimulates osteoblastic maturation and inhibits myogenic differentiation in vitro J. Cell Biol., 113, pp. 681-687. [CSA] [CROSSREF]
    • (1991) J. Cell Biol. , vol.113 , pp. 681-687
    • Yamaguchi, A.1    Katagiri, T.2    Ikeda, T.3    Wozney, J.4    Rosen, V.5    Wang, E.6    Kahn, A.7    Suda, T.8    Yoshiki, S.9
  • 7
    • 0025114650 scopus 로고
    • The non-osteogenic mouse pluripotent cell line, C3H10T1/2, is induced to differentiate into osteoblastic cells by recombinant human bone morphogenetic protein-2
    • [CSA] [CROSSREF]
    • Katagiri, T. and Yamaguchi, A. and Ikeda, T. and Yoshiki, S. and Wozney, J. and Rosen, V. and Wang, E. and Tanaka, H. and Omura, S. and Suda, T. (1990) The non-osteogenic mouse pluripotent cell line, C3H10T1/2, is induced to differentiate into osteoblastic cells by recombinant human bone morphogenetic protein-2 Biochem. Biophys. Res. Commun., 172, pp. 295-299. [CSA] [CROSSREF]
    • (1990) Biochem. Biophys. Res. Commun. , vol.172 , pp. 295-299
    • Katagiri, T.1    Yamaguchi, A.2    Ikeda, T.3    Yoshiki, S.4    Wozney, J.5    Rosen, V.6    Wang, E.7    Tanaka, H.8    Omura, S.9    Suda, T.10
  • 8
    • 0029737070 scopus 로고    scopus 로고
    • Bone morphogenetic proteins: Multifunctional regulators of vertebrate development
    • [CSA]
    • Hogan, B. (1996) Bone morphogenetic proteins: Multifunctional regulators of vertebrate development Genes Dev., 10, pp. 1580-1594. [CSA]
    • (1996) Genes Dev. , vol.10 , pp. 1580-1594
    • Hogan, B.1
  • 9
    • 0035971201 scopus 로고    scopus 로고
    • Transcriptional mechanisms of bone morphogenetic protein-induced osteoprotegrin gene expression
    • [CSA] [CROSSREF]
    • Wan, M. and Shi, X. and Feng, X. and Cao, X. (2001) Transcriptional mechanisms of bone morphogenetic protein-induced osteoprotegrin gene expression J. Biol. Chem., 276, pp. 10119-10125. [CSA] [CROSSREF]
    • (2001) J. Biol. Chem. , vol.276 , pp. 10119-10125
    • Wan, M.1    Shi, X.2    Feng, X.3    Cao, X.4
  • 11
    • 0034703619 scopus 로고    scopus 로고
    • Identification of a novel fibroblast growth factor, FGF-23, preferentially expressed in the ventrolateral thalamic nucleus of the brain
    • [CSA] [CROSSREF]
    • Yamashita, T. and Yoshioka, M. and Itoh, N. (2000) Identification of a novel fibroblast growth factor, FGF-23, preferentially expressed in the ventrolateral thalamic nucleus of the brain Biochem. Biophys. Res. Commun., 277, pp. 494-498. [CSA] [CROSSREF]
    • (2000) Biochem. Biophys. Res. Commun. , vol.277 , pp. 494-498
    • Yamashita, T.1    Yoshioka, M.2    Itoh, N.3
  • 12
    • 0024339705 scopus 로고
    • The heparin-binding (fibroblast) growth factor family of proteins
    • [CSA] [CROSSREF]
    • Burgess, W. and Maciag, T. (1989) The heparin-binding (fibroblast) growth factor family of proteins Annu. Rev. Biochem., 58, pp. 575-606. [CSA] [CROSSREF]
    • (1989) Annu. Rev. Biochem. , vol.58 , pp. 575-606
    • Burgess, W.1    Maciag, T.2
  • 13
    • 0024370274 scopus 로고
    • Recent developments in the cell biology of basic fibroblast growth factor
    • [CSA] [CROSSREF]
    • Rifkin, D. and Moscatelli, D. (1989) Recent developments in the cell biology of basic fibroblast growth factor J. Cell. Biol., 109, pp. 1-6. [CSA] [CROSSREF]
    • (1989) J. Cell. Biol. , vol.109 , pp. 1-6
    • Rifkin, D.1    Moscatelli, D.2
  • 14
    • 0025738048 scopus 로고
    • The fibroblast growth factor family
    • [CSA]
    • Baird, A. and Klagsbrun, M. (1991) The fibroblast growth factor family Cancer Cells, 3, pp. 239-243. [CSA]
    • (1991) Cancer Cells , vol.3 , pp. 239-243
    • Baird, A.1    Klagsbrun, M.2
  • 15
    • 0000651536 scopus 로고    scopus 로고
    • Dual-mode regulation of hair growth cycle by two Fgf-5 gene products
    • [CSA] [CROSSREF]
    • Suzuki, S. and Ota, Y. and Ozawa, K. and Imamura, T. (2000) Dual-mode regulation of hair growth cycle by two Fgf-5 gene products J. Invest. Dermatol., 114, pp. 456-463. [CSA] [CROSSREF]
    • (2000) J. Invest. Dermatol. , vol.114 , pp. 456-463
    • Suzuki, S.1    Ota, Y.2    Ozawa, K.3    Imamura, T.4
  • 16
    • 0023755196 scopus 로고
    • Effects of bone associated growth factors on DNA, collagen and osteocalcin synthesis in cultured fetal rat calvariae
    • [CSA] [CROSSREF]
    • Canalis, E. and Lian, J. (1988) Effects of bone associated growth factors on DNA, collagen and osteocalcin synthesis in cultured fetal rat calvariae Bone, 9, pp. 243-246. [CSA] [CROSSREF]
    • (1988) Bone , vol.9 , pp. 243-246
    • Canalis, E.1    Lian, J.2
  • 17
    • 0026703367 scopus 로고
    • The interaction of heparin and basic fibroblast growth factor on collagen synthesis in 21-day fetal rat calvariae
    • [CSA] [CROSSREF]
    • Hurley, M. and Kessler, M. and Gronowicz, G. and Raisz, L. (1992) The interaction of heparin and basic fibroblast growth factor on collagen synthesis in 21-day fetal rat calvariae Endocrinology, 130, pp. 2675-2682. [CSA] [CROSSREF]
    • (1992) Endocrinology , vol.130 , pp. 2675-2682
    • Hurley, M.1    Kessler, M.2    Gronowicz, G.3    Raisz, L.4
  • 18
    • 0026332453 scopus 로고
    • Effects of acid and basic fibroblast growth factor and heparin on resorption of cultured fetal rat long bones
    • [CSA]
    • Simmons, H. and Raisz, L. (1991) Effects of acid and basic fibroblast growth factor and heparin on resorption of cultured fetal rat long bones J. Bone Miner. Res., 6, pp. 1301-1305. [CSA]
    • (1991) J. Bone Miner. Res. , vol.6 , pp. 1301-1305
    • Simmons, H.1    Raisz, L.2
  • 19
    • 0023899261 scopus 로고
    • Effects of basic fibroblast growth factor on bone formation in-vitro
    • [CSA]
    • Canalis, E. and Centrella, M. and McCarthy, T. (1988) Effects of basic fibroblast growth factor on bone formation in-vitro J. Clin. Invest., 81, pp. 1572-1577. [CSA]
    • (1988) J. Clin. Invest. , vol.81 , pp. 1572-1577
    • Canalis, E.1    Centrella, M.2    McCarthy, T.3
  • 20
    • 0024310168 scopus 로고
    • Opposing effects of fibroblast growth factor and pertussis toxin on alkaline phosphatase, osteopontin, osteocalcin, and type I collagen mRNA levels in ROS 17/2.8 cells
    • [CSA]
    • Rodan, S. and Wesolowski, G. and Yoon, K. and Rodan, G. (1989) Opposing effects of fibroblast growth factor and pertussis toxin on alkaline phosphatase, osteopontin, osteocalcin, and type I collagen mRNA levels in ROS 17/2.8 cells J. Biol. Chem., 264, pp. 19934-19941. [CSA]
    • (1989) J. Biol. Chem. , vol.264 , pp. 19934-19941
    • Rodan, S.1    Wesolowski, G.2    Yoon, K.3    Rodan, G.4
  • 21
    • 0027506158 scopus 로고
    • Basic fibroblast growth factor inhibits type I collagen gene expression in osteoblastic MC3T3-E1 cells
    • [CSA]
    • Hurley, M. and Abreu, C. and Harrison, J. and Lichtler, A. and Raisz, L. and Kream, B. (1993) Basic fibroblast growth factor inhibits type I collagen gene expression in osteoblastic MC3T3-E1 cells J. Biol. Chem., 268, pp. 5588-5593. [CSA]
    • (1993) J. Biol. Chem. , vol.268 , pp. 5588-5593
    • Hurley, M.1    Abreu, C.2    Harrison, J.3    Lichtler, A.4    Raisz, L.5    Kream, B.6
  • 22
    • 0028291066 scopus 로고
    • Expression and regulation of basic fibroblast growth factor mRNA levels in mouse osteoblastic MC3T3-E1 cells
    • [CSA]
    • Hurley, M. and Abreu, C. and Gronowicz, G. and Kawaguchi, H. and Lorenzo, J. (1994) Expression and regulation of basic fibroblast growth factor mRNA levels in mouse osteoblastic MC3T3-E1 cells J. Biol. Chem., 269, pp. 9392-9396. [CSA]
    • (1994) J. Biol. Chem. , vol.269 , pp. 9392-9396
    • Hurley, M.1    Abreu, C.2    Gronowicz, G.3    Kawaguchi, H.4    Lorenzo, J.5
  • 23
    • 0034613242 scopus 로고    scopus 로고
    • Fibroblast growth factor (FGF)-2 directly stimulates mature osteoclast function through activation of FGF receptor 1 and p42/p44 MAP kinase
    • [CSA] [CROSSREF]
    • Chikazu, D. and Hakeda, Y. and Ogata, N. and Nemoto, K. and Itabashi, A. and Takato, T. and Kumegawa, M. and Nakamura, K. and Kawaguchi, H. (2000) Fibroblast growth factor (FGF)-2 directly stimulates mature osteoclast function through activation of FGF receptor 1 and p42/p44 MAP kinase J. Biol. Chem., 275, pp. 31444-31450. [CSA] [CROSSREF]
    • (2000) J. Biol. Chem. , vol.275 , pp. 31444-31450
    • Chikazu, D.1    Hakeda, Y.2    Ogata, N.3    Nemoto, K.4    Itabashi, A.5    Takato, T.6    Kumegawa, M.7    Nakamura, K.8    Kawaguchi, H.9
  • 24
    • 0034007871 scopus 로고    scopus 로고
    • Direct and indirect actions of fibroblast growth factor 2 on osteoclastic bone resorption in cultures
    • [CSA] [CROSSREF]
    • Kawaguchi, H. and Chikazu, D. and Nakamura, K. and Kumegawa, M. and Hakeda, Y. (2000) Direct and indirect actions of fibroblast growth factor 2 on osteoclastic bone resorption in cultures J. Bone Miner. Res., 15, pp. 466-473. [CSA] [CROSSREF]
    • (2000) J. Bone Miner. Res. , vol.15 , pp. 466-473
    • Kawaguchi, H.1    Chikazu, D.2    Nakamura, K.3    Kumegawa, M.4    Hakeda, Y.5
  • 28
    • 0033556175 scopus 로고    scopus 로고
    • IL-18 is produced by articular chondrocytes and induces proinflammatory and catabolic responses
    • [CSA]
    • Olee, T. and Hashimoto, S. and Quach, J. and Lotz, M. (1999) IL-18 is produced by articular chondrocytes and induces proinflammatory and catabolic responses J. Immunol, 162, pp. 1096-1100. [CSA]
    • (1999) J. Immunol , vol.162 , pp. 1096-1100
    • Olee, T.1    Hashimoto, S.2    Quach, J.3    Lotz, M.4
  • 29
    • 17544389276 scopus 로고    scopus 로고
    • Interleukin-18 (interferon-gamma-inducing factor) is produced by osteoblasts and acts via granulocyte/macrophage colony-stimulating factor and not via interferon-gamma to inhibit osteoclast formation
    • [CSA] [CROSSREF]
    • Udagawa, N. and Horwood, N. and Elliott, J. and Mackay, A. and Owens, J. and Okamura, H. and Kurimoto, M. and Chambers, T. and Martin, T. and Gillespie, M. (1997) Interleukin-18 (interferon-gamma-inducing factor) is produced by osteoblasts and acts via granulocyte/macrophage colony-stimulating factor and not via interferon-gamma to inhibit osteoclast formation J. Exp. Med., 185, pp. 1005-1012. [CSA] [CROSSREF]
    • (1997) J. Exp. Med. , vol.185 , pp. 1005-1012
    • Udagawa, N.1    Horwood, N.2    Elliott, J.3    Mackay, A.4    Owens, J.5    Okamura, H.6    Kurimoto, M.7    Chambers, T.8    Martin, T.9    Gillespie, M.10
  • 30
    • 0020678843 scopus 로고
    • In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria
    • [CSA] [CROSSREF]
    • Sudo, H. and Kodama, H. and Amagai, Y. and Yamamoto, S. and Kasai, S. (1983) In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria J. Cell. Biol., 96, pp. 191-198. [CSA] [CROSSREF]
    • (1983) J. Cell. Biol. , vol.96 , pp. 191-198
    • Sudo, H.1    Kodama, H.2    Amagai, Y.3    Yamamoto, S.4    Kasai, S.5
  • 31
    • 0026543172 scopus 로고
    • Relationship between collagen synthesis and expression of the osteoblast phenotype in MC3T3-E1 cells
    • [CSA]
    • Franceschi, R. and Iyer, B. (1992) Relationship between collagen synthesis and expression of the osteoblast phenotype in MC3T3-E1 cells J. Bone Miner. Res., 7, pp. 235-246. [CSA]
    • (1992) J. Bone Miner. Res. , vol.7 , pp. 235-246
    • Franceschi, R.1    Iyer, B.2
  • 32
    • 0026690364 scopus 로고
    • Distinct proliferative and differentiated stages of murine MC3T3-E1 cells in culture: An in vitro model of osteoblast development
    • [CSA]
    • Quarles, L. and Yohay, D. and Lever, L. and Caton, R. and Wenstrup, R. (1992) Distinct proliferative and differentiated stages of murine MC3T3-E1 cells in culture: An in vitro model of osteoblast development J. Bone Miner. Res., 7, pp. 683-692. [CSA]
    • (1992) J. Bone Miner. Res. , vol.7 , pp. 683-692
    • Quarles, L.1    Yohay, D.2    Lever, L.3    Caton, R.4    Wenstrup, R.5
  • 34
    • 0024365860 scopus 로고
    • Interleukin-6 is produced by bone and modulated by parathyroid hormone
    • [CSA]
    • Feyen, J. and Elford, P. and Di Padova, F. and Trechsel, U. (1989) Interleukin-6 is produced by bone and modulated by parathyroid hormone J. Bone Miner. Res., 4, pp. 633-638. [CSA]
    • (1989) J. Bone Miner. Res. , vol.4 , pp. 633-638
    • Feyen, J.1    Elford, P.2    Di Padova, F.3    Trechsel, U.4
  • 35
    • 0024404268 scopus 로고
    • Parathyroid hormone (PTH) and PTH-like protein (PLP) stimulate interleukin-6 production by osteogenic cells: A possible role of interleukin-6 in osteoclastogenesis
    • [CSA] [CROSSREF]
    • Lowik, C. and van der Pluijm, G. and Bloys, H. and Hoekman, K. and Bijvoet, O. and Aarden, L. and Papapoulos, S. (1989) Parathyroid hormone (PTH) and PTH-like protein (PLP) stimulate interleukin-6 production by osteogenic cells: A possible role of interleukin-6 in osteoclastogenesis Biochem. Biophys. Res. Commun., 162, pp. 1546-1552. [CSA] [CROSSREF]
    • (1989) Biochem. Biophys. Res. Commun. , vol.162 , pp. 1546-1552
    • Lowik, C.1    van der Pluijm, G.2    Bloys, H.3    Hoekman, K.4    Bijvoet, O.5    Aarden, L.6    Papapoulos, S.7
  • 36
    • 0036297847 scopus 로고    scopus 로고
    • FGF-2 increases colony formation, PTH receptor, and IGF-1 mRNA in mouse marrow stromal cells
    • [CSA] [CROSSREF]
    • Zhang, X. and Sobue, T. and Hurley, M. (2002) FGF-2 increases colony formation, PTH receptor, and IGF-1 mRNA in mouse marrow stromal cells Biochem. Biophys. Res. Commun., 290, pp. 526-531. [CSA] [CROSSREF]
    • (2002) Biochem. Biophys. Res. Commun. , vol.290 , pp. 526-531
    • Zhang, X.1    Sobue, T.2    Hurley, M.3
  • 37
    • 0034815599 scopus 로고    scopus 로고
    • Interleukin-1 regulates FGF-2 mRNA and localization of FGF-2 protein in human osteoblasts
    • [CSA] [CROSSREF]
    • Sobue, T. and Zhang, X. and Florkiewicz, R. and Hurley, M. (2001) Interleukin-1 regulates FGF-2 mRNA and localization of FGF-2 protein in human osteoblasts Biochem. Biophys. Res. Commun., 286, pp. 33-40. [CSA] [CROSSREF]
    • (2001) Biochem. Biophys. Res. Commun. , vol.286 , pp. 33-40
    • Sobue, T.1    Zhang, X.2    Florkiewicz, R.3    Hurley, M.4
  • 38
    • 0032578611 scopus 로고    scopus 로고
    • Osteoprotegerin production by human osteoblast lineage cells is stimulated by vitamin D, bone morphogenetic protein-2, and cytokines
    • [CSA] [CROSSREF]
    • Hofbauer, L. and Dunstan, C. and Spelsberg, T. and Riggs, B. and Khosla, S. (1998) Osteoprotegerin production by human osteoblast lineage cells is stimulated by vitamin D, bone morphogenetic protein-2, and cytokines Biochem. Biophys. Res. Commun., 250, pp. 776-781. [CSA] [CROSSREF]
    • (1998) Biochem. Biophys. Res. Commun. , vol.250 , pp. 776-781
    • Hofbauer, L.1    Dunstan, C.2    Spelsberg, T.3    Riggs, B.4    Khosla, S.5
  • 39
    • 0032836036 scopus 로고    scopus 로고
    • Counter regulation of interleukin-18 mRNA and protein expression during cutaneous wound repair in mice
    • [CSA] [CROSSREF]
    • Kampfer, H. and Kalina, U. and Muhl, H. and Pfeilschifter, J. and Frank, S. (1999) Counter regulation of interleukin-18 mRNA and protein expression during cutaneous wound repair in mice J. Invest. Dermatol., 113, pp. 369-374. [CSA] [CROSSREF]
    • (1999) J. Invest. Dermatol. , vol.113 , pp. 369-374
    • Kampfer, H.1    Kalina, U.2    Muhl, H.3    Pfeilschifter, J.4    Frank, S.5
  • 40
    • 0034523052 scopus 로고    scopus 로고
    • Regulation of interleukin-18 (IL-18) expression in keratinocytes (HaCaT): Implications for early wound healing
    • [CSA]
    • Kampfer, H. and Muhl, H. and Manderscheid, M. and Kalina, U. and Kauschat, D. and Pfeilschifter, J. and Frank, S. (2000) Regulation of interleukin-18 (IL-18) expression in keratinocytes (HaCaT): Implications for early wound healing Eur. Cytokine Netw., 11, pp. 626-633. [CSA]
    • (2000) Eur. Cytokine Netw. , vol.11 , pp. 626-633
    • Kampfer, H.1    Muhl, H.2    Manderscheid, M.3    Kalina, U.4    Kauschat, D.5    Pfeilschifter, J.6    Frank, S.7
  • 41
    • 0036436851 scopus 로고    scopus 로고
    • Bacterial infection of osteoblasts induces interleukin-1beta and interleukin-18 transcription but not protein synthesis
    • [CSA] [CROSSREF]
    • Marriott, I. and Hughes, F. and Bost, K. (2002) Bacterial infection of osteoblasts induces interleukin-1beta and interleukin-18 transcription but not protein synthesis J. Interferon Cytokine Res., 22, pp. 1049-1055. [CSA] [CROSSREF]
    • (2002) J. Interferon Cytokine Res. , vol.22 , pp. 1049-1055
    • Marriott, I.1    Hughes, F.2    Bost, K.3
  • 42
    • 0033514959 scopus 로고    scopus 로고
    • Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1beta are differentially regulated in human blood mononuclear cells and mouse spleen cells
    • [CSA] [CROSSREF]
    • Puren, A. and Fantuzzi, G. and Dinarello, C. (1999) Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1beta are differentially regulated in human blood mononuclear cells and mouse spleen cells Proc. Natl. Acad. Sci. USA, 96, pp. 2256-2261. [CSA] [CROSSREF]
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 2256-2261
    • Puren, A.1    Fantuzzi, G.2    Dinarello, C.3
  • 43
    • 1642432081 scopus 로고    scopus 로고
    • IL-6, RANKL, NF-alpha/IL-1: Interrelations in bone resorption pathophysiology
    • [CSA] [CROSSREF]
    • Kwan Tat, S. and Padrines, M. and Theoleyre, S. and Heymann, D. and Fortun, Y. (2004) IL-6, RANKL, NF-alpha/IL-1: Interrelations in bone resorption pathophysiology Cytokine Growth Factor Rev., 15, pp. 49-60. [CSA] [CROSSREF]
    • (2004) Cytokine Growth Factor Rev. , vol.15 , pp. 49-60
    • Kwan, T.S.1    Padrines, M.2    Theoleyre, S.3    Heymann, D.4    Fortun, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.