The neurosecretory system is hypertrophied in senescence-accelerated mice

Rejuvenation Research

Volumn 9, Issue 2, 2006, Pages 297-301

  Crespo, Damaso ^a,b   Megias, Manuel ^a   Fernandez Viadero, Carlos ^a   Alonso, Laura ^a   Verduga, Rosario ^a  

^a UNIVERSITY OF CANTABRIA   (Spain)

^b UNIVERSITY OF CANTABRIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ARGIPRESSIN; NEUROHORMONE; OXYTOCIN;

AGING; AMYLOIDOSIS; ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTERIOR HYPOTHALAMUS; CIRCADIAN RHYTHM; CONFERENCE PAPER; CONTROLLED STUDY; FEMALE; HORMONE SYNTHESIS; HYPOTHALAMUS; MALE; MEMORY DISORDER; MOUSE; NEUROSECRETION; NEUROSECRETORY CELL; NONHUMAN; PRIORITY JOURNAL; SENESCENCE; STEREOLOGY; SUPRACHIASMATIC NUCLEUS; SUPRAOPTIC NUCLEUS;

AGING; ANIMALS; HYPERTROPHY; HYPOTHALAMUS, ANTERIOR; IMMUNOHISTOCHEMISTRY; MICE; MODELS, ANIMAL; NEURONS; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS;

EID: 33744962017     PISSN: 15491684     EISSN: None     Source Type: Journal    
DOI: 10.1089/rej.2006.9.297     Document Type: Conference Paper

References (16)

1. Swanson LW, Sawchenko PE. Hypothalamic integration: organization of the paraventricular and supraoptic nuclei. Annu Rev Neurosci 1983;6:269-324.
2. Pickering BT, Swann RW, Gonzalez CB. Biosynthesis and processing of neurohypophysial hormones. Pharmacol Ther 1983;22:143-161.
3. Scharrer B. Neurosecretion: beginnings and new directions in neuropeptide research. Annu Rev Neurosci 1987;10:1-17.
4. Swaab DF. Neuropeptides in hypothalamic neuronal disorders. Int Rev Cytol 2004;240:305-375.
5. Bernardis LL, Davis PJ. Aging and the hypothalamus: research perspectives. Physiol Behav 1996;59:523-536.
6. Keck ME, Holsboer F, Muller MB. Mouse mutants for the study of corticotropin-releasing hormone receptor function: development of novel treatment strategies for mood disorders. Ann NY Acad Sci 2004;1018:445-457.
7. Odagiri Y, Uchida H, Hosokawa M, Takemoto K, Morley AA, Takeda T. Accelerated accumulation of somatic mutations in the senescence-accelerated mouse. Nat Genet 1998;19:116-117.
8. Takeda T. Senescence-accelerated mouse (SAM): a biogerontological resource in aging research. Neurobiol Aging 1999;20:105-110.
9. Takeshita S, Hosokawa M, Irind M, Higuchi K, Shimizu K, Yasuhira K, Takeda T. Spontaneous age-associated amyloidosis in senescence-accelerated mouse (SAM). Mech Aging Dev 1982;20:13-23.
10. Sanchez-Barcelo EJ, Megias M, Verduga R, Crespo D. Differences between the circadian system of two strains of senescence-accelerated mice (SAM). Physiol Behav 1997;62:1225-1229.
11. Insausti AM, Megias M, Crespo D, Cruz-Orive LM, Dierssen M, Vallina IF, Insausti R, Florez J. Hippocampal volume and neuronal number in Ts65Dn mice: a murine model of Down syndrome. Neurosci Lett 1998;253:175-178.
12. Cruz-Orive L, Insausti AM, Insausti R, Crespo D. A case study from neuroscience involving stereology and multivariate analysis. In: Evans SM, Janson AM, Nyengaard JE, eds. Quantitative Methods in Neuroscience: A Neuroanatomical Approach. Oxford, UK: Oxford University Press, 2004:16-64.
13. Castel M, Morris JF. The neurophysin-containing innervation of the forebrain of the mouse. Neuroscience 1988;24:937-966.
14. Reppert SM, Weaver DR. Molecular analysis of mammalian circadian rhythms. Annu Rev Physiol 2001;63:647-676.
15. Dierickx K, De Waele G. Scanning electron microscopy of the wall of the third ventricle of the brain of Rana temporaria. III. Electron microscopy of the ventricular surface of the median eminence. Cell Tissue Res 1975;161:343-349.
16. Keck ME, Hatzinger M, Wotjak CT, Landgraf R, Holsboer F, Neumann ID. Aging alters intrahypothalamic release patterns of vasopressin and oxytocin in rats. Eur J Neurosci 2000;12:1487-1494.