High productivity of t-PA in CHO cells using hypoxia response element

Journal of Microbiology and Biotechnology

Volumn 16, Issue 5, 2006, Pages 695-703

  Bae, Gun Won ^a   Jeong, Dae Won ^b   Kim, Hong Jin ^c   Lee, Gyun Min ^d   Park, Hongwoo ^e   Choe, Tae Boo ^f   Kang, Seongman ^a   Kim, Ick Young ^a   Kim, Ik Hwan ^a  

^a Korea University   (South Korea)

^b Seoul National University   (South Korea)

^c Chung Ang University   (South Korea)

^d Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^e Division of Applied Chemical Engineering and Bio Engineering   (South Korea)

^f Department of Microbiological Engineering ^*  (South Korea)

Author keywords

Chinese hamster ovary cell; Hypoxia; Hypoxia inducible factor 1 ; Hypoxia response element; Immobilized cells; Tissue type plasminogen activator

Indexed keywords

ALGINIC ACID; BARIUM ION; COMPLEMENTARY DNA; RECOMBINANT PROTEIN; TISSUE PLASMINOGEN ACTIVATOR;

AERATION; ANIMAL CELL; ARTICLE; BACTERIUM CULTURE; CELL SUSPENSION; CHO CELL; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; EXPRESSION VECTOR; GENE CONSTRUCT; GENETIC ENHANCEMENT; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYPOXIA; IMMOBILIZED CELL CULTURE; MAMMAL; NONHUMAN; PROTEIN SYNTHESIS;

MAMMALIA;

EID: 33744949570     PISSN: 10177825     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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