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Volumn 2, Issue 3, 2006, Pages 153-154

Development of a disease-modifying treatment for Alzheimer's disease: Alzhemed

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; BIOLOGICAL MARKER; CHOLINESTERASE INHIBITOR; HOMOTAURINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NOOTROPIC AGENT; TAU PROTEIN; UNCLASSIFIED DRUG;

EID: 33744906292     PISSN: 15525260     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jalz.2006.03.009     Document Type: Editorial
Times cited : (3)

References (9)
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    • Aisen P.S. The development of anti-amyloid therapy for Alzheimer's disease. from secretase modulators to polymerisation inhibitors. CNS Drugs 19 (2005) 989-996
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    • Aisen, P.S.1
  • 2
    • 0030865454 scopus 로고    scopus 로고
    • Slowing the progression of Alzheimer disease. Methodologic issues
    • Leber P. Slowing the progression of Alzheimer disease. Methodologic issues. Alzheimer Dis Assoc Disord 11 Suppl 5 (1997) S10-S20
    • (1997) Alzheimer Dis Assoc Disord , vol.11 , Issue.SUPPL. 5
    • Leber, P.1
  • 3
    • 0034820554 scopus 로고    scopus 로고
    • Glycosaminoglycan mimetics. A therapeutic approach to cerebral amyloid angiopathy
    • 2001
    • Gervais F., Chalifour R., Garceau D., Kong X., Laurin J., et al. Glycosaminoglycan mimetics. A therapeutic approach to cerebral amyloid angiopathy. 2001. Amyloid 8 Suppl 1 (2001) 28-35
    • (2001) Amyloid , Issue.8 SUPPL. 1 , pp. 28-35
    • Gervais, F.1    Chalifour, R.2    Garceau, D.3    Kong, X.4    Laurin, J.5
  • 4
    • 13544255842 scopus 로고    scopus 로고
    • Clinical data on Alzhemed after 12 months of treatment in patients with mild to moderate Alzheimer's disease
    • Aisen P.S., Mehran M., Poole R., Lavoie I., Gervais F., et al. Clinical data on Alzhemed after 12 months of treatment in patients with mild to moderate Alzheimer's disease. Neurobiol Aging 25 (2004) 20
    • (2004) Neurobiol Aging , vol.25 , pp. 20
    • Aisen, P.S.1    Mehran, M.2    Poole, R.3    Lavoie, I.4    Gervais, F.5
  • 5
    • 27944471285 scopus 로고    scopus 로고
    • Binding of the positron emission tomography tracer Pittsburgh compound-B reflects the amount of amyloid-beta in Alzheimer's disease brain but not in transgenic mouse brain
    • Klunk W.E., Lopresti B.J., Ikonomovic M.D., Lefterov I.M., Koldamova R.P., et al. Binding of the positron emission tomography tracer Pittsburgh compound-B reflects the amount of amyloid-beta in Alzheimer's disease brain but not in transgenic mouse brain. J Neurosci 25 (2005) 10598-10606
    • (2005) J Neurosci , vol.25 , pp. 10598-10606
    • Klunk, W.E.1    Lopresti, B.J.2    Ikonomovic, M.D.3    Lefterov, I.M.4    Koldamova, R.P.5
  • 7
    • 19944430290 scopus 로고    scopus 로고
    • Dynamics of {beta}-amyloid reductions in brain, cerebrospinal fluid and plasma of {beta}-amyloid precursor protein transgenic mice treated with a {gamma}-secretase inhibitor
    • Barten D.M., Guss V.L., Corsa J.A., Loo A.T., Hansel S.B., et al. Dynamics of {beta}-amyloid reductions in brain, cerebrospinal fluid and plasma of {beta}-amyloid precursor protein transgenic mice treated with a {gamma}-secretase inhibitor. J Pharmacol Exp Ther 312 (2004) 635-643
    • (2004) J Pharmacol Exp Ther , vol.312 , pp. 635-643
    • Barten, D.M.1    Guss, V.L.2    Corsa, J.A.3    Loo, A.T.4    Hansel, S.B.5
  • 8
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    • In vivo characterisation of A{beta}(40) changes in brain and CSF using the novel {gamma}-secretase inhibitor MRK-560 (N-[cis-4-[(4-chlorophenyl)sulfonyl]-4- (2,5-difluorophenyl)cyclohexyl]-1,1,1- trifluoromethanesulfonamide) in the rat
    • Best J.D., Jay M.T., Otu F., Churcher I., Reilly M., et al. In vivo characterisation of A{beta}(40) changes in brain and CSF using the novel {gamma}-secretase inhibitor MRK-560 (N-[cis-4-[(4-chlorophenyl)sulfonyl]-4- (2,5-difluorophenyl)cyclohexyl]-1,1,1- trifluoromethanesulfonamide) in the rat. J Pharmacol Exp Ther 317 (2006) 786-790
    • (2006) J Pharmacol Exp Ther , vol.317 , pp. 786-790
    • Best, J.D.1    Jay, M.T.2    Otu, F.3    Churcher, I.4    Reilly, M.5
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    • Alzheimer's disease abeta vaccine reduces central nervous system abeta levels in a non-human primate, the Caribbean vervet
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    • Lemere C.A., Beierschmitt A., Iglesias M., Spooner E.T., Bloom J.K., et al. Alzheimer's disease abeta vaccine reduces central nervous system abeta levels in a non-human primate, the Caribbean vervet. 2004. Am J Pathol 165 (2004) 283-297
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    • Lemere, C.A.1    Beierschmitt, A.2    Iglesias, M.3    Spooner, E.T.4    Bloom, J.K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.