Prostaglandin involvement in lung C-fiber activation by substance P in guinea pigs

Journal of Applied Physiology

Volumn 100, Issue 6, 2006, Pages 1918-1927

  Bergren, Dale R ^a  

^a CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

C fiber activity

Indexed keywords

BRADYKININ; BRADYKININ ANTAGONIST; CAPSAICIN; ICATIBANT; INDOMETACIN; PROSTAGLANDIN; SUBSTANCE P;

ANIMAL EXPERIMENT; ARTERIAL PRESSURE; ARTICLE; ASTHMA; CELL ACTIVATION; CONTROLLED STUDY; GUINEA PIG; HEART RATE; LUNG ALVEOLUS CELL; LUNG PRESSURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; RESPIRATORY AIRFLOW;

ACTION POTENTIALS; ADRENERGIC BETA-ANTAGONISTS; ANIMALS; ASTHMA; BLOOD PRESSURE; BRADYKININ; CAPSAICIN; CYCLOOXYGENASE INHIBITORS; DINOPROST; DINOPROSTONE; GUINEA PIGS; HEART RATE; INDOMETHACIN; LUNG; NERVE FIBERS, UNMYELINATED; PROSTAGLANDINS; RESPIRATORY HYPERSENSITIVITY; SUBSTANCE P;

EID: 33744906278     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.01276.2005     Document Type: Article

References (33)

1. Amann R, Schuligoi R, and Peskar BA. Effects of COX-1 and COX-2 inhibitors on eicosanoid biosynthesis and the release of substance P from guinea pig isolated perfused lung. Inflamm Res 50: 50-53, 2001.
2. Barnes PJ. Asthma as an axon reflex. Lancet 1: 242-245, 1986.
3. Bergren DR. Sensory receptor activation by mediators of defense reflexes in guinea-pig lungs. Respir Physiol 108: 195-204, 1997.
4. Bergren DR. Enhanced lung C-fiber responsiveness in sensitized adult guinea pigs exposed to chronic tobacco smoke. J Appl Physiol 91: 1645-1654, 2001.
5. Bergren DR. Investigation of lung C-fiber activation by substance P, capsaicin and bradykinin in guinea pigs (Abstract). Am J Respir Crit Care Med 167: A708, 2003.
6. Bergren DR, Gustafson JM, and Myers DL. Effect of prostaglandin F2 alpha on pulmonary rapidly-adapting-receptors in the guinea pig. Prostaglandins 27: 391-405, 1984.
7. Bergren DR and Peterson DF. Identification of vagal sensory receptors in the rat lung: are there subtypes of slowly adapting receptors? J Physiol 464: 681-689, 1993.
8. Bodelsson M, Blomquist S, Caverius K, and Tornebrandt K. Substance P relaxes rat bronchial smooth muscle via epithelial prostanoid synthesis. Respiration 66: 355-359, 1999.
9. Brunelleschi S, Vanni L, Ledda F, Giotti A, Maggi CA, and Fantozzi R. Tachykinins activate guinea-pig alveolar macrophages: involvement of NK2 and NK1 receptors. Br J Pharmacol 100: 417-420, 1990.
10. Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, and Julius D. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389: 816-824, 1997.
11. Chapman RW, Hey JA, McLeod R, Minnicozzi M, and Rizzo C. Tachykinins in the lungs. Drug News Perspect 11: 480-489, 1998.
12. Coleridge HM, Coleridge JC, Baker DG, Ginzel KH, and Morrison MA. Comparison of the effects of histamine and prostaglandin on afferent C-fiber endings and irritant receptors in the intrapulmonary airways. Adv Exp Med Biol 99: 291-305, 1978.
13. Coleridge HM, Coleridge JC, and Luck JC. Pulmonary afferent fibres of small diameter stimulated by capsaicin and by hyperinflation of the lungs. J Physiol 179: 248-262, 1965.
14. Coleridge HM, Coleridge JC, and Schultz HD. Afferent pathways involved in reflex regulation of airway smooth muscle. Pharmacol Ther 42: 1-63, 1989.
15. Fox AJ, Barnes PJ, Urban L, and Dray A. An in vitro study of the properties of single vagal afferent innervating guinea pig airways. J Physiol 469: 21-35, 1993.
16. Garland A, Necheles J, White SR, Neeley SP, Leff AR, Carson SS, Alger LE, McAllister K, and Solway J. Activated eosinophils elicit substance P release from cultured dorsal root ganglion neurons. Am J Physiol Lung Cell Mol Physiol 273: L1096-L1102, 1997.
17. 4 in the guinea pig in vivo. Prostaglandins 25: 405-412, 1983.
18. 2 enhances chemical and mechanical sensitivities of pulmonary C fibers in the rat. Am J Respir Crit Care Med 162: 528-533, 2000.
19. Holzer P. Capsaicin: cellular targets, mechanisms of action, and selectivity for thin sensory neurons. Pharmacol Rev 43: 143-201, 1991.
20. Hwang SW, Cho H, Kwak J, Lee SY, Kang CJ, Jung J, Cho S, Min KH, Suh YG, Kim D, and Oh U. Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances. Proc Natl Acad Sci USA 97: 6155-6160, 2000.
21. Kajekar R, Proud D, Myers AC, Meeker SN, and Undem BJ. Characterization of vagal afferent subtypes stimulated by bradykinin in guinea pig trachea. J Pharmacol Exp Ther 289: 682-687, 1999.
22. Kaufman MP, Coleridge HM, Coleridge JC, and Baker DG. Bradykinin stimulates afferent vagal C fibers in intrapulmonary airways of dogs. J Appl Physiol 48: 511-517, 1980.
23. Kollarik M and Undem BJ. Activation of bronchopulmonary vagal afferent nerves with bradykinin, acid and vanilloid receptor agonists in wild-type and TRPV1-/- mice. J Physiol 555: 115-123, 2004.
24. 2 sensitizes cultured pulmonary vagal sensory neurons to chemical and electrical stimuli. J Appl Physiol 93: 1419-1428, 2002.
25. 2 in anesthetized rats. J Appl Physiol 79: 1679-1686, 1995.
26. Lilly CM, Hall AE, Rodger IW, Kobzik L, Haley KJ, and Drazen JM. Substance P-induced histamine release in tracheally perfused guinea pig lungs. J Appl Physiol 78: 1234-1241, 1995.
27. 2. J Appl Physiol 58: 1823-1831, 1985.
28. Saria A, Martling CR, Yan Z, Theodorsson-Norheim E, Gamse R, and Lundberg JM. Release of multiple tachykinins from capsaicin-sensitive sensory nerves in the lungs by bradykinin, histamine, dimethylphenyl piperazinium and vagal nerve stimulation. Am Rev Respir Dis 137: 1330-1335, 1988.
29. Spina D and Page CP. Asthma - a need for a rethink? Trends Pharmacol Sci 23: 311-315, 2002.
30. Strigas J and Burcher E. Autoradiographic localization of tachykinin NK2 and NK1 receptors in the guinea-pig lung, using selective radioligands. Eur J Pharmacol 311: 177-186, 1996.
31. Szarek JL, Spurlock B, Gruetter CA, and Lemke S. Substance P and capsaicin release prostaglandin E2 from rat intrapulmonary bronchi. Am J Physiol Lung Cell Mol Physiol 275: L1006-L1012, 1998.
32. Van Schoor J, Joos GF, and Pauwels RA. Indirect bronchial hyperresponsiveness in asthma: mechanisms, pharmacology and implications for clinical research. Eur Respir J 16: 514-533, 2000.
33. Weinreich D, Koschorke GM, Undem BJ, and Taylor GE. Prevention of the excitatory actions of bradykinin by inhibition of PGI2 formation in nodose neurons of the guinea-pig. J Physiol 483: 735-746, 2002.