Hindbrain chemical mediators of reflex-induced inhibition of gastric tone produced by esophageal distension and intravenous nicotine

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 289, Issue 5 58-5, 2005, Pages

  Ferreira Jr , Manuel ^a   Sahibzada, Niaz ^a   Shi, Min ^a   Niedringhaus, Mark ^a   Wester, Matthew R ^a   Jones, Allison ^a   Verbalis, Joseph G ^a   Gillis, Richard A ^a  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

2 adrenoreceptor; c Fos; Central nervous system; Dorsal motor nucleus of the vagus; Esophageal distension; Medial subnucleus of the tractus solitarii; Nitric oxide synthase; Vagus nerves

Indexed keywords

ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; N(G) NITROARGININE METHYL ESTER; NICOTINE; NITRIC OXIDE; NORADRENALIN; PROTEIN C FOS;

ABDOMINAL DISTENSION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ESOPHAGUS DISEASE; ESOPHAGUS DISTENSION; IMMUNOCYTOCHEMISTRY; MALE; MEDIATOR RELEASE; MICROINJECTION; NITRERGIC NERVE; NONHUMAN; NORADRENERGIC NERVE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RHOMBENCEPHALON; SOLITARY TRACT NUCLEUS; STOMACH MOTILITY; STOMACH PRESSURE; TOBACCO DEPENDENCE; VAGUS REFLEX;

ANIMALS; ENZYME INHIBITORS; ESOPHAGUS; GASTROINTESTINAL MOTILITY; IMMUNOHISTOCHEMISTRY; INJECTIONS, INTRAVENOUS; MALE; MODELS, BIOLOGICAL; NEURAL INHIBITION; NEURONS; NG-NITROARGININE METHYL ESTER; NICOTINE; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, SPRAGUE-DAWLEY; REFLEX; RHOMBENCEPHALON; SOLITARY NUCLEUS; VAGUS NERVE;

EID: 27144449941     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.00003.2005     Document Type: Article

References (58)

1. Abrahamsson H and Jansson G. Elicitation of reflex vagal relaxation of the stomach from pharynx and esophagus in the cat. Acta Physiol Scand 11: 172-178, 1969.
2. Andrews PL. The non-adrenergic non-cholinergic innervation of the stomach. Arch Int Pharmacodyn Ther 280: 84-109, 1986.
3. Andrews PL, Bingham S, and Wood KL. Modulation of the vagal drive to the intramural cholinergic and non-cholinergic neurones in the ferret stomach by baclofen. J Physiol 388: 25-39, 1987.
4. Beleslin DB and Strbac M. Noradrenaline-induced emesis. Alpha-2 adrenoceptor mediation in the area postrema. Neuropharmacology 26: 1157-1165, 1987.
5. 2-adrenoceptors inhibit excitatory synaptic transmission in rat brain stem. Am J Physiol Gastrointest Liver Physiol 212: G654-G661, 1997.
6. Chang HY, Mashimo H, and Goyal RK. Musings on the wanderer: what's new in our understanding of vago-vagal reflex? IV. Current concepts of vagal efferent projections to the gut. Am J Physiol Gastrointest Liver Physiol 284: G357-G366, 2003.
7. Davis SF, Derbenev AV, Williams KW, Glatzer NR, and Smith BN. Excitatory and inhibitory local circuit input to the rat dorsal motor nucleus of the vagus originating from the nucleus tractus solitarius. Brain Res 1017: 208-217, 2004.
8. De Ponti F, Azpiroz F, and Malagelada JR. Relaxatory responses of canine proximal stomach to esophageal and duodenal distension: importance of vagal pathways. Dig Dis Sci 34: 873-881, 1989.
9. Derbenev AV, Stuart TC, and Smith BN. Cannabinoids suppress synaptic input to neurones of the rat dorsal motor nucleus of the vagus nerve. J Physiol 559: 923-938, 2004.
10. Feldman PD and Felder RB. Alpha 2-adrenergic modulation of synaptic excitability in the rat nucleus tractus solitarius. Brain Res 480: 190-197, 1989.
11. Feldman PD and Felder RB. Alpha-adrenergic influences on neuronal responses to visceral afferent input in the nucleus tractus solitarius. Neuropharmacology 28: 1081-1087, 1989.
12. Ferreira M Jr, Sahibzada N, Shi M, Panico W, Niedringhaus M, Wasserman A, Kellar KJ, Verbalis J, and Gillis RA. CNS site of action and brainstem circuitry responsible for the intravenous effects of nicotine on gastric tone. J Neurosci 22: 2764-2779, 2002.
13. Ferreira M, Singh A, Dretchen KL, Kellar KJ, and Gillis RA. Brainstem nicotinic receptor subtypes that influence intragastric and arterial blood pressures. J Pharmacol Exp Ther 294: 230-238, 2000.
14. Fukuda A, Minami T, Nabekura J, and Oomura Y. The effects of noradrenaline on neurones in the rat dorsal motor nucleus of the vagus, in vitro. J Physiol 393: 213-231, 1987.
15. Garthwaite J and Garthwaite G. Cellular origins of cyclic GMP responses to excitatory amino acid receptor agonists in rat cerebellum in vitro. J Neurochem 48: 29-39, 1987.
16. Grundy D. Vagal control of gastrointestinal function. Baillieres Clin Gastroenterol 2: 23-43, 1988.
17. Hoffman GE, Smith MS, and Verbalis JG. c-Fos and related immediate early gene products as markers of activity in neuroendocrine systems. Front Neuroendocrinol 14: 173-213, 1993.
18. Hornby PJ. Receptors and transmission in the brain-gut axis. II. Excitatory amino acid receptors in the brain-gut axis. Am J Physiol Gastrointest Liver Physiol 280: G1055-G1060, 2001.
19. Ishiguchi T, Nakajima M, Sone H, Tada H, Kumagai AK, and Takahashi T. Gastric distension-induced pyloric relaxation: central nervous system regulation and effects of acute hyperglycaemia in the rat. J Physiol 533: 801-813, 2001.
20. Jahnberg T, Abrahamsson H, Jansson G, and Martinson J. Vagal gastric relaxation in the dog. Scand J Gastroenterol 12: 221-224, 1977.
21. Jansson G. Vago-vagal reflex relaxation of the stomach in the cat. Acta Physiol Scand 75: 245-252, 1969.
22. Krowicki ZK, Sharkey KA, Serron SC, Nathan NA, and Hornby PJ. Distribution of nitric oxide synthase in rat dorsal vagal complex and effects of microinjection of nitric oxide compounds upon gastric motor function. J Comp Neurol 377: 49-69, 1997.
23. Loewy AD, McKellar S, and Saper CB. Direct projections from the A5 catecholamine cell group to the intermediolateral cell column. Brain Res 174: 309-314, 1979.
24. Martinez-Peña y Valenzuela I, Rogers RC, Hermann GE, and Travagli RA. Norepinephrine effects on identified neurons of the rat dorsal motor nucleus of the vagus. Am J Physiol Gastrointest Liver Physiol 286: G333-G339, 2004.
25. McCann MJ and Rogers RC. Functional and chemical anatomy of a gastric vago-vagal reflex. In: Innervation of the Gut: Pathophysiological Implications, edited by Tache Y, Wingate DL and Burks TF. Boca Raton, FL: CRC, 1994, p. 81-92.
26. Moore SD and Guyenet PG. Alpha-receptor mediated inhibition of A2 noradrenergic neurons. Brain Res 276: 188-191, 1983.
27. O'Dell TJ, Hawkins RD, Kandel ER, and Arancio O. Tests of the roles of two diffusible substances in long-term potentiation: evidence for nitric oxide as a possible early retrograde messenger. Proc Natl Acad Sci USA 88: 11285-11289, 1991.
28. Okada D, Yap CC, Kojima H, Kikuchi K, and Nagano T. Distinct glutamate receptors govern differential levels of nitric oxide production in a layer-specific manner in the rat cerebellar cortex. Neuroscience 125: 461-472, 2004.
29. Okumura T and Namiki M. Vagal motor neurons innervating the stomach are site-specifically organized in the dorsal motor nucleus of the vagus nerve in rats. J Auton Nerv Syst 29: 157-162, 1990.
30. Osumi Y, Ishikawa T, Okuma Y, Nagasaka Y, and Fujiwara M. Inhibition of gastric functions by stimulation of rat locus coeruleus. Eur J Pharmacol 75: 27-35, 1981.
31. Paxinos G, Carrive P, Wang H, and Wang P-Y. Chemoarchitectonic Atlas of the Rat Brainstem. New York: Academic, 1999.
32. Paxinos G and Watson C. The Rat Brain in Stereotaxic Coordinates. New York: Academic, 1998.
33. Pickel VM, Chan J, Park DH, Joh TH, and Milner TA. Ultrastructural localization of phenylethanolamine N-methyltransferase in sensory and motor nuclei of the vagus nerve. J Neurosci Res 15: 439-455, 1986.
34. Rea MA, Aprison MH, and Felten DL. Catecholamines and serotonin in the caudal medulla of the rat: combined neurochemical-histofluorescence study. Brain Res Bull 9: 227-236, 1982.
35. Rogers RC, Hermann GE, and Travagli RA. Brainstem pathways responsible for oesophageal control of gastric motility and tone in the rat. J Physiol 514: 369-383, 1999.
36. Rogers RC and McCann MJ. Intramedullary connections of the gastric region in the solitary nucleus: a biocytin histochemical tracing study in the rat. J Auton Nerv Syst 42: 119-130, 1993.
37. Rogers RC, McTigue DM, and Hermann GE. Vagal control of digestion: modulation by central neural and peripheral endocrine factors. Neurosci Biobehav Rev 20: 57-66, 1996.
38. Rogers RC, McTigue DM, and Hermann GE. Vagovagal reflex control of digestion: afferent modulation by neural and "endoneurocrine" factors. Am J Physiol Gastrointest Liver Physiol 268: G1-G10, 1995.
39. Rogers RC, Travagli RA, and Hermann GE. Noradrenergic neurons in the rat solitary nucleus participate in the esophageal-gastric relaxation reflex. Am J Physiol Regul Integr Comp Physiol 285: R479-R489, 2003.
40. Rosin DL, Talley EM, Lee A, Stornetta RL, Gaylinn BD, Guyenet PG, and Lynch KR. Distribution of alpha 2C-adrenergic receptor-like immunoreactivity in the rat central nervous system. J Comp Neurol 372: 135-165, 1996.
41. Sawchenko PE and Swanson LW. The organization of noradrenergic pathways from the brainstem to the paraventricular and supraoptic nuclei in the rat. Brain Res 257: 275-325, 1982.
42. Shi M, Jones AR, Ferreira M Jr, Sahibzada N, Gillis RA, and Verbalis JG. Glucose does not activate nonadrenergic, noncholinergic inhibitory neurons in the rat stomach. Am J Physiol Regul Integr Comp Physiol 288: R742-R750, 2005.
43. Siaud P, Denoroy L, Assenmacher I, and Alonso G. Comparative immunocytochemical study of the catecholaminergic and peptidergic afferent innervation to the dorsal vagal complex in rat and guinea pig. J Comp Neurol 290: 323-335, 1989.
44. Sumal KK, Blessing WW, Joh TH, Reis DJ, and Pickel VM. Synaptic interaction of vagal afferents and catecholaminergic neurons in the rat nucleus tractus solitarius. Brain Res 277: 31-40, 1983.
45. Takahashi T and Owyang C. Vagal control of nitric oxide and vasoactive intestinal polypeptide release in the regulation of gastric relaxation in rat. J Physiol 484: 481-492, 1995.
46. Takahashi Y, Satoh K, Sakumoto T, Tohyama M, and Shimizu N. A major source of catecholamine terminals in the nucleus tractus solitarii. Brain Res 172: 372-377, 1979.
47. Takayama K, Suzuki T, and Miura M. The comparison of effects of various anesthetics on expression of Fos protein in the rat brain. Neurosci Lett 176: 59-62, 1994.
48. Ter Horst GJ, Toes GJ, and Van Willigen JD. Locus coeruleus projections to the dorsal motor vagus nucleus in the rat. Neuroscience 45: 153-160, 1991.
49. Torres JE, Kreisman NR, and Gozal D. Nitric oxide modulates in vitro intrinsic optical signal and neural activity in the nucleus tractus solitarius of the rat. Neurosci Lett 232: 175-178, 1997.
50. Travagli RA and Gillis RA. Nitric oxide-mediated excitatory effect on neurons of dorsal motor nucleus of vagus. Am J Physiol Gastrointest Liver Physiol 266: G154-G160, 1994.
51. Travagli RA, Gillis RA, Rossiter CD, and Vicini S. Glutamate and GABA-mediated synaptic currents in neurons of the rat dorsal motor nucleus of the vagus. Am J Physiol Gastrointest Liver Physiol 260: G531-G536, 1991.
52. Travagli RA, Hermann GE, Browning KN, and Rogers RC. Musings on the wanderer: what's new in our understanding of vago-vagal reflexes? III. Activity-dependent plasticity in vago-vagal reflexes controlling the stomach. Am J Physiol Gastrointest Liver Physiol 284: G180-G187, 2003.
53. Travagli RA and Rogers RC. Receptors and transmission in the brain-gut axis: potential for novel therapies. V. Fast and slow extrinsic modulation of dorsal vagal complex circuits. Am J Physiol Gastrointest Liver Physiol 281: G595-G601, 2001.
54. Wasserman AM, Ferreira M Jr, Sahibzada N, Hernandez YM, and Gillis RA. GABA-mediated neurotransmission in the ventrolateral NTS plays a role in respiratory regulation in the rat. Am J Physiol Regul Integr Comp Physiol 283: R1423-R1441, 2002.
55. Watson RE Jr, Wiegand SJ, Clough RW, and Hoffman GE. Use of cryoprotectant to maintain long-term peptide immunoreactivity and tissue morphology. Peptides 7: 155-159, 1986.
56. Westlund KN and Coulter JD. Descending projections of the locus coeruleus and subcoeruleus/medial parabrachial nuclei in monkey: axonal transport studies and dopamine-beta-hydroxylase immunocytochemistry. Brain Res 2: 235-264, 1980.
57. Willing AE and Berthoud HR. Gastric distension-induced c-fos expression in catecholaminergic neurons of rat dorsal vagal complex. Am J Physiol Regul Integr Comp Physiol 272: R59-R67, 1997.
58. Zhang X and Fogel R. Involvement of glutamate in gastrointestinal vago-vagal reflexes initiated by gastrointestinal distention in the rat. Auton Neurosci 103: 19-37, 2003.