Intestinal permeability and excretion into bile control the arrival of amlodipine into the systemic circulation after oral administration

Journal of Pharmacy and Pharmacology

Volumn 58, Issue 6, 2006, Pages 827-836

  Raušl, Dragica ^a   Fotaki, Nikoletta ^b   Zanoški, Ružica ^a   Vertzoni, Maria ^b   Cetina Čižmek, Biserka ^a   Khan, M Zahirul I ^a   Reppas, Christos ^b  

^a PLIVA CROATIA LTD   (Croatia)

^b UNIVERSITY OF ATHENS   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

AMLODIPINE BESYLATE; PROPRANOLOL; RANITIDINE;

ARTICLE; CELL STRAIN CACO 2; CONTROLLED STUDY; DRUG BILE LEVEL; DRUG FORMULATION; DRUG PENETRATION; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INTESTINE MUCOSA PERMEABILITY; NORMAL HUMAN; SYSTEMIC CIRCULATION; TABLET;

ADMINISTRATION, ORAL; ADULT; AMLODIPINE; BILE; CALCIUM CHANNEL BLOCKERS; HUMANS; HYDROGEN-ION CONCENTRATION; INTESTINES; MEMBRANES, ARTIFICIAL; PERMEABILITY; SOLUBILITY;

EID: 33744787344     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.58.6.0013     Document Type: Article

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