A high-throughput screening assay for the carboxyltransferase subunit of acetyl-CoA carboxylase

Analytical Biochemistry

Volumn 354, Issue 1, 2006, Pages 70-77

  Santoro, Nicholas ^a   Brtva, Teresa ^a   Roest, Steve Vander ^a   Siegel, Karen ^a   Waldrop, Grover L ^b  

^a PFIZER INC   (United States)

^b LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

Acetyl CoA carboxylase; Antibiotics; Biotin; Carboxyltransferase; High throughput screening

Indexed keywords

ANTIBIOTICS; BIOCHEMISTRY; BIOSYNTHESIS; CARBOXYLATION; CATALYSIS; ESCHERICHIA COLI; FATTY ACIDS;

ACETYL-COA CARBOXYLASE; BIOSYNTHETIC PATHWAY; BIOTIN; BIOTIN CARBOXYL CARRIER PROTEIN; CARBOXYLTRANSFERASE; FATTY ACID BIOSYNTHESIS; HIGH THROUGHPUT SCREENING; SPECTROPHOTOMETRIC READ-OUT;

COENZYMES;

5,5' DITHIOBIS(2 NITROBENZOIC ACID); ACETYL COENZYME A; ACETYL COENZYME A CARBOXYLASE; ANTIBIOTIC AGENT; BIOCYTIN; BIOTIN; CARBOXYLTRANSFERASE; CARRIER PROTEIN; CITRATE SYNTHASE; CITRIC ACID; COENZYME A; ENZYME INHIBITOR; MALONYL COENZYME A; NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE;

ARTICLE; ASSAY; ENZYME MECHANISM; ENZYME SUBUNIT; HIGH THROUGHPUT SCREENING; LABORATORY DIAGNOSIS; PRIORITY JOURNAL; SPECTROPHOTOMETRY; ULTRAVIOLET SPECTROSCOPY; VALIDATION PROCESS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 33744527478     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2006.04.006     Document Type: Article

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