메뉴 건너뛰기




Volumn 60, Issue 6, 2006, Pages 707-715

Clinical evidence for use of acetyl salicylic acid in control of flushing related to nicotinic acid treatment

Author keywords

Acetylsalicylic acid; Discontinuation; Flushing; Nicotinic acid

Indexed keywords

ACETYLSALICYLIC ACID; ARACHIDONIC ACID; COLESTYRAMINE; CYCLOOXYGENASE 1 INHIBITOR; DICLOFENAC; FLUINDOSTATIN; GEMFIBROZIL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IBUPROFEN; INDOMETACIN; LEUKOTRIENE B4 RECEPTOR ANTAGONIST; NICOTINIC ACID; NIFLUMIC ACID; NONSTEROID ANTIINFLAMMATORY AGENT; PLACEBO; PRAVASTATIN; PROSTAGLANDIN; SIMVASTATIN;

EID: 33744516859     PISSN: 13685031     EISSN: 17421241     Source Type: Journal    
DOI: 10.1111/j.1368-5031.2006.00957.x     Document Type: Review
Times cited : (41)

References (65)
  • 1
    • 1842681535 scopus 로고    scopus 로고
    • New perspectives on the use of niacin in the treatment of lipid disorders
    • McKenney J. New perspectives on the use of niacin in the treatment of lipid disorders. Arch Intern Med 2004; 164: 697-705.
    • (2004) Arch Intern Med , vol.164 , pp. 697-705
    • McKenney, J.1
  • 3
    • 0037352280 scopus 로고    scopus 로고
    • PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect
    • Tunaru S, Kero J, Schaub A et al. PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect. Nat Med 2003; 9: 352-5.
    • (2003) Nat Med , vol.9 , pp. 352-355
    • Tunaru, S.1    Kero, J.2    Schaub, A.3
  • 4
    • 0003293442 scopus 로고    scopus 로고
    • Molecular identification of high and low affinity receptors for nicotinic acid
    • Wise A, Foord SM, Fraser NJ et al. Molecular identification of high and low affinity receptors for nicotinic acid. J Biol Chem 2003; 278: 9869-74.
    • (2003) J Biol Chem , vol.278 , pp. 9869-9874
    • Wise, A.1    Foord, S.M.2    Fraser, N.J.3
  • 5
    • 2942564118 scopus 로고    scopus 로고
    • The nicotinic acid receptor - A new mechanism for an old drug
    • Karpe F, Frayn KN. The nicotinic acid receptor - a new mechanism for an old drug. Lancet 2004; 363: 1892-4.
    • (2004) Lancet , vol.363 , pp. 1892-1894
    • Karpe, F.1    Frayn, K.N.2
  • 6
    • 3042626597 scopus 로고    scopus 로고
    • Identification of a nicotinic acid receptor. Is that the molecular target for the oldest lipid-lowering drug?
    • Pike NB, Wise A. Identification of a nicotinic acid receptor. is that the molecular target for the oldest lipid-lowering drug? Curr Opin Investig Drugs 2004; 5: 271-5.
    • (2004) Curr Opin Investig Drugs , vol.5 , pp. 271-275
    • Pike, N.B.1    Wise, A.2
  • 7
    • 1242322495 scopus 로고    scopus 로고
    • Stimulation of CD36 and the key effector of reverse cholesterol transport ATP-binding cassette A1 in monocytoid cells by niacin
    • Rubic T, Trottmann M, Lorenz RL. Stimulation of CD36 and the key effector of reverse cholesterol transport ATP-binding cassette A1 in monocytoid cells by niacin. Biochem Pharmacol 2004; 67: 411-9.
    • (2004) Biochem Pharmacol , vol.67 , pp. 411-419
    • Rubic, T.1    Trottmann, M.2    Lorenz, R.L.3
  • 8
    • 0342549693 scopus 로고
    • Niacin in vascular disorders and hyperlipemia
    • Altschul R, ed. IL, USA: Charles C Thomas
    • Altschul R. Niacin in vascular disorders and hyperlipemia. Altschul R, ed. IL, USA: CharlPs C Thomas, 1964: pp 3-135.
    • (1964) , pp. 3-135
    • Altschul, R.1
  • 9
    • 0014546955 scopus 로고
    • The relationship between the plasma concentration of free nicotinic acid and some of its pharmacologic effects in man
    • Svedmyr N, Harthon L, Lundholm L. The relationship between the plasma concentration of free nicotinic acid and some of its pharmacologic effects in man. Clin Pharmacol Ther 1969; 10: 559-70.
    • (1969) Clin Pharmacol Ther , vol.10 , pp. 559-570
    • Svedmyr, N.1    Harthon, L.2    Lundholm, L.3
  • 10
    • 0015079217 scopus 로고
    • Thermographic registration of flush
    • Åberg G, Svedmyr N. Thermographic registration of flush. Arzneimittelforschung 1971; 21: 795-6.
    • (1971) Arzneimittelforschung , vol.21 , pp. 795-796
    • Åberg, G.1    Svedmyr, N.2
  • 11
    • 33744551128 scopus 로고
    • Inhibition of flush induced by nicotinic acid
    • Åberg G. Inhibition of flush induced by nicotinic acid. Int Res Commun 1973; 1: 13.
    • (1973) Int Res Commun , vol.1 , pp. 13
    • Åberg, G.1
  • 13
    • 0026508010 scopus 로고
    • Identification of skin as a major site of prostaglandin D2 release following oral administration of niacin in humans
    • Morrow JD, Awad JA, Oates JA, Roberts LJ. Identification of skin as a major site of prostaglandin D2 release following oral administration of niacin in humans. J Invest Dermatol 1992; 98: 812-5.
    • (1992) J Invest Dermatol , vol.98 , pp. 812-815
    • Morrow, J.D.1    Awad, J.A.2    Oates, J.A.3    Roberts, L.J.4
  • 14
    • 0032977431 scopus 로고    scopus 로고
    • Nicotinic acid and pyridoxine modulate arachidonic acid metabolism in vitro and ex vivo in man
    • Saareks V, Mucha I, Sievi E, Riutta A. Nicotinic acid and pyridoxine modulate arachidonic acid metabolism in vitro and ex vivo in man. Pharmacol Toxicol 1999; 84: 274-80.
    • (1999) Pharmacol Toxicol , vol.84 , pp. 274-280
    • Saareks, V.1    Mucha, I.2    Sievi, E.3    Riutta, A.4
  • 15
    • 31044448925 scopus 로고    scopus 로고
    • GPR109A (PUMA-G/HM74A) mediates nicotinic acid-induced flushing
    • BenyóZ, Gille A, Kero J et al. GPR109A (PUMA-G/HM74A) mediates nicotinic acid-induced flushing. J Clin Invest 2005; 115: 3634-40.
    • (2005) J Clin Invest , vol.115 , pp. 3634-3640
    • Benyó, Z.1    Gille, A.2    Kero, J.3
  • 16
    • 0026553160 scopus 로고
    • The effect of aspirin on niacin-induced cutaneous reactions
    • Whelan AM, Price SO, Fowler SF, Hainer BL. The effect of aspirin on niacin-induced cutaneous reactions. J Fam Pract 1992; 34: 165-8.
    • (1992) J Fam Pract , vol.34 , pp. 165-168
    • Whelan, A.M.1    Price, S.O.2    Fowler, S.F.3    Hainer, B.L.4
  • 17
    • 0038630864 scopus 로고    scopus 로고
    • Niacin for dyslipidemia: Considerations for product selection
    • McKenney J. Niacin for dyslipidemia: Considerations for product selection. Am J Health Syst Pharm 2003; 60: 995-1005.
    • (2003) Am J Health Syst Pharm , vol.60 , pp. 995-1005
    • McKenney, J.1
  • 18
    • 0030054668 scopus 로고    scopus 로고
    • Acute dose-dependent disposition studies of nicotinic acid in rats
    • Iwaki M, Ogiso T, Hayashi H et al. Acute dose-dependent disposition studies of nicotinic acid in rats. Drug Metab Dispos 1996; 24: 773-9.
    • (1996) Drug Metab Dispos , vol.24 , pp. 773-779
    • Iwaki, M.1    Ogiso, T.2    Hayashi, H.3
  • 19
    • 0024799035 scopus 로고
    • Pharmacokinetics of nicotinic acid-salicylic acid interaction
    • Ding RW, Kolbe K, Merz B et al. Pharmacokinetics of nicotinic acid-salicylic acid interaction. Clin Pharmacol Ther 1989; 46: 642-7.
    • (1989) Clin Pharmacol Ther , vol.46 , pp. 642-647
    • Ding, R.W.1    Kolbe, K.2    Merz, B.3
  • 20
    • 0034700636 scopus 로고    scopus 로고
    • The pharmacokinetics and pharmacodynamics of agents proven to raise high-density lipoprotein cholesterol
    • Piepho RW. The pharmacokinetics and pharmacodynamics of agents proven to raise high-density lipoprotein cholesterol. Am J Cardiol 2000; 86 (Suppl.): 35L-40L.
    • (2000) Am J Cardiol , vol.86 , Issue.SUPPL.
    • Piepho, R.W.1
  • 21
    • 0642344305 scopus 로고    scopus 로고
    • Overview of niacin formulations. Differences in pharmacokinetics, efficacy, and safety
    • Pieper JA. Overview of niacin formulations. differences in pharmacokinetics, efficacy, and safety. Am J Health Syst Pharm 2003; 60: S9-S14.
    • (2003) Am J Health Syst Pharm , vol.60
    • Pieper, J.A.1
  • 22
    • 0030764837 scopus 로고    scopus 로고
    • Effect of two aspirin pretreatment regimens on niacin-induced cutaneous reactions
    • Jungnickel PW, Maloley PA, Vander Tuin EL et al. Effect of two aspirin pretreatment regimens on niacin-induced cutaneous reactions. J Gen Intern Med 1997; 12: 591-6.
    • (1997) J Gen Intern Med , vol.12 , pp. 591-596
    • Jungnickel, P.W.1    Maloley, P.A.2    Vander Tuin, E.L.3
  • 23
    • 0020307552 scopus 로고
    • Aspirin blocks nicotinic acid-induced flushing
    • Wilkin JK, Wilkin O, Kapp R et al. Aspirin blocks nicotinic acid-induced flushing. Clin Pharmacol Ther 1982; 31: 478-82.
    • (1982) Clin Pharmacol Ther , vol.31 , pp. 478-482
    • Wilkin, J.K.1    Wilkin, O.2    Kapp, R.3
  • 24
    • 1842338863 scopus 로고
    • Low-dose aspirin and ibuprofen reduce the cutaneous reactions following niacin administration
    • Dunn RT, Ford MA, Rindone JP, Kwiecinski FA. Low-dose aspirin and ibuprofen reduce the cutaneous reactions following niacin administration. Am J Ther 1995; 2: 478-80.
    • (1995) Am J Ther , vol.2 , pp. 478-480
    • Dunn, R.T.1    Ford, M.A.2    Rindone, J.P.3    Kwiecinski, F.A.4
  • 25
    • 0021828236 scopus 로고
    • Contrasting effects of unmodified and time-release forms of niacin on lipoproteins in hyperlipidemic subjects: Clues to mechanism of action of niacin
    • Knopp RH, Ginsberg J, Albers JJ et al. Contrasting effects of unmodified and time-release forms of niacin on lipoproteins in hyperlipidemic subjects: Clues to mechanism of action of niacin. Metabolism 1985; 34: 642-50.
    • (1985) Metabolism , vol.34 , pp. 642-650
    • Knopp, R.H.1    Ginsberg, J.2    Albers, J.J.3
  • 26
    • 85047692711 scopus 로고
    • Niacin revisited. A randomized, controlled trial of wax-matrix sustained-release niacin in hypercholesterolemia
    • Keenan JM, Fontaine PL, Wenz JB et al. Niacin revisited. A randomized, controlled trial of wax-matrix sustained-release niacin in hypercholesterolemia. Arch Intern Med 1991; 151: 1424-32.
    • (1991) Arch Intern Med , vol.151 , pp. 1424-1432
    • Keenan, J.M.1    Fontaine, P.L.2    Wenz, J.B.3
  • 27
    • 0028343111 scopus 로고
    • Fluvastatin with and without niacin for hypercholesterolemia
    • Jacobson TA, Chin MM, Fromell GJ et al. Fluvastatin with and without niacin for hypercholesterolemia. Am J Cardiol 1994; 74: 149-54.
    • (1994) Am J Cardiol , vol.74 , pp. 149-154
    • Jacobson, T.A.1    Chin, M.M.2    Fromell, G.J.3
  • 28
    • 0028527139 scopus 로고
    • Complementary effects of pravastatin and nicotinic acid in the treatment of combined hyperlipidaemia in diabetic and non-diabetic patients
    • Tsalamandris C, Panagiotopoulos S, Sinha A et al. Complementary effects of pravastatin and nicotinic acid in the treatment of combined hyperlipidaemia in diabetic and non-diabetic patients. J Cardiovasc Risk 1994; 1: 231-9.
    • (1994) J Cardiovasc Risk , vol.1 , pp. 231-239
    • Tsalamandris, C.1    Panagiotopoulos, S.2    Sinha, A.3
  • 29
    • 0028012746 scopus 로고
    • Comparative efficacy and safety of pravastatin, nicotinic acid and the two combined in patients with hypercholesterolemia
    • Davignon J, Roederer G, Montigny M et al. Comparative efficacy and safety of pravastatin, nicotinic acid and the two combined in patients with hypercholesterolemia. Am J Cardiol 1994; 73: 339-45.
    • (1994) Am J Cardiol , vol.73 , pp. 339-345
    • Davignon, J.1    Roederer, G.2    Montigny, M.3
  • 30
    • 0030917574 scopus 로고    scopus 로고
    • Combination of low-dose niacin and pravastatin improves the lipid profile in diabetic patients without compromising glycemic control
    • Gardner SF, Marx MA, White LM et al. Combination of low-dose niacin and pravastatin improves the lipid profile in diabetic patients without compromising glycemic control. Ann Pharmacother 1997; 31: 677-82.
    • (1997) Ann Pharmacother , vol.31 , pp. 677-682
    • Gardner, S.F.1    Marx, M.A.2    White, L.M.3
  • 31
    • 0030662291 scopus 로고    scopus 로고
    • Experience with crystalline niacin as the preferred drug for dyslipidemia in a specialty clinic
    • Rindone JP, Arriola OG. Experience with crystalline niacin as the preferred drug for dyslipidemia in a specialty clinic. Pharmacotherapy 1997; 17: 1296-9.
    • (1997) Pharmacotherapy , vol.17 , pp. 1296-1299
    • Rindone, J.P.1    Arriola, O.G.2
  • 32
    • 0032542302 scopus 로고    scopus 로고
    • Efficacy and safety of an extended-release niacon (Niaspan): A long-term study
    • Capuzzi DM, Guyton JR, Morgan JM et al. Efficacy and safety of an extended-release niacon (Niaspan): A long-term study. Am J Cardiol 1998; 82: 74U-81U.
    • (1998) Am J Cardiol , vol.82
    • Capuzzi, D.M.1    Guyton, J.R.2    Morgan, J.M.3
  • 33
    • 2442425776 scopus 로고    scopus 로고
    • Equivalent efficacy of a time-release form of niacin (Niaspan) given once-a-night versus plain niacin in the management of hyperlipidemia
    • Knopp RH, Alagona P, Davidson M et al. Equivalent efficacy of a time-release form of niacin (Niaspan) given once-a-night versus plain niacin in the management of hyperlipidemia. Metabolism 1998; 47: 1097-104.
    • (1998) Metabolism , vol.47 , pp. 1097-1104
    • Knopp, R.H.1    Alagona, P.2    Davidson, M.3
  • 34
    • 0032530770 scopus 로고    scopus 로고
    • Effectiveness of once-nightly dosing of extended-release niacin alone and in combination for hypercholesterolemia
    • Guyton JR, Goldberg AC, Kreisberg RA et al. Effectiveness of once-nightly dosing of extended-release niacin alone and in combination for hypercholesterolemia. Am J Cardiol 1998; 82: 737-43.
    • (1998) Am J Cardiol , vol.82 , pp. 737-743
    • Guyton, J.R.1    Goldberg, A.C.2    Kreisberg, R.A.3
  • 35
    • 0033765889 scopus 로고    scopus 로고
    • Effective and safe modification of multiple atherosclerotic risk factors in patients with peripheral arterial disease
    • Garg R, Elam MB, Crouse JR III et al. Effective and safe modification of multiple atherosclerotic risk factors in patients with peripheral arterial disease. Am Heart J 2000; 140: 792-803.
    • (2000) Am Heart J , vol.140 , pp. 792-803
    • Garg, R.1    Elam, M.B.2    Crouse III, J.R.3
  • 36
    • 0034708959 scopus 로고    scopus 로고
    • Extended release niacin vs gemfibrozil for the treatment of low levels of high density lipoprotein cholesterol
    • Guyton JR, Blazing MA, Hagar J et al. Extended release niacin vs gemfibrozil for the treatment of low levels of high density lipoprotein cholesterol. Arch Intern Med 2000; 160: 1177-84.
    • (2000) Arch Intern Med , vol.160 , pp. 1177-1184
    • Guyton, J.R.1    Blazing, M.A.2    Hagar, J.3
  • 37
    • 0034191863 scopus 로고    scopus 로고
    • Multiple-dose efficacy and safety of an extended-release form of niacin in the management of hyperlipidemia
    • Goldberg A, Alagona P Jr, Capuzzi DM et al. Multiple-dose efficacy and safety of an extended-release form of niacin in the management of hyperlipidemia. Am J Cardiol 2000; 85: 1100-5.
    • (2000) Am J Cardiol , vol.85 , pp. 1100-1105
    • Goldberg, A.1    Alagona Jr., P.2    Capuzzi, D.M.3
  • 38
    • 0035423283 scopus 로고    scopus 로고
    • Effect of niacin and atorvastatin on lipoprotein subclasses in patients with atherogenic dyslipidemia
    • McKenney JM, McCormick LS, Schaefer EJ et al. Effect of niacin and atorvastatin on lipoprotein subclasses in patients with atherogenic dyslipidemia. Am J Cardiol 2001; 88: 270-4.
    • (2001) Am J Cardiol , vol.88 , pp. 270-274
    • McKenney, J.M.1    McCormick, L.S.2    Schaefer, E.J.3
  • 39
    • 0037158150 scopus 로고    scopus 로고
    • Efficacy, safety, and tolerability of once-daily niacin for the treatment of dyslipidemia associated with type 2 diabetes: Results of the assessment of diabetes control and evaluation of the efficacy of Niaspan trial
    • Grundy SM, Vega GL, McGovern ME et al. Efficacy, safety, and tolerability of once-daily niacin for the treatment of dyslipidemia associated with type 2 diabetes: Results of the assessment of diabetes control and evaluation of the efficacy of Niaspan trial. Arch Intern Med 2002; 162: 1568-76.
    • (2002) Arch Intern Med , vol.162 , pp. 1568-1576
    • Grundy, S.M.1    Vega, G.L.2    McGovern, M.E.3
  • 40
    • 0035991486 scopus 로고    scopus 로고
    • Niacin treatment of the atherogenic lipid profile and Lp (a) in diabetes
    • Pan J, Lin M, Kesala RL et al. Niacin treatment of the atherogenic lipid profile and Lp (a) in diabetes. Diabetes Obes Metab 2002; 4: 255-61.
    • (2002) Diabetes Obes Metab , vol.4 , pp. 255-261
    • Pan, J.1    Lin, M.2    Kesala, R.L.3
  • 41
    • 0037086184 scopus 로고    scopus 로고
    • Long-term safety and efficacy of a once-daily niacin/lovastatin formulation for patients with dyslipidemia
    • Kashyap ML, McGovern ME, Berra K et al. Long-term safety and efficacy of a once-daily niacin/lovastatin formulation for patients with dyslipidemia. Am J Cardiol 2002; 89: 672-8.
    • (2002) Am J Cardiol , vol.89 , pp. 672-678
    • Kashyap, M.L.1    McGovern, M.E.2    Berra, K.3
  • 42
    • 0037443567 scopus 로고    scopus 로고
    • ADvicor Versus Other Cholesterol-Modulating Agents Trial Evaluation. Comparison of once-daily, niacin extended-release/lovastatin with standard doses of atorvastatin and simvastatin (the ADvicor Versus Other Cholesterol-Modulating Agents Trial Evaluation [ADVOCATE])
    • Bays HE, Dujovne CA, McGovern ME et al. ADvicor Versus Other Cholesterol-Modulating Agents Trial Evaluation. Comparison of once-daily, niacin extended-release/lovastatin with standard doses of atorvastatin and simvastatin (the ADvicor Versus Other Cholesterol-Modulating Agents Trial Evaluation [ADVOCATE]). Am J Cardiol 2003; 91: 667-72.
    • (2003) Am J Cardiol , vol.91 , pp. 667-672
    • Bays, H.E.1    Dujovne, C.A.2    McGovern, M.E.3
  • 43
    • 0037343026 scopus 로고    scopus 로고
    • A dose-ranging study of a new, once-daily, dual-component drug product containing niacin extended-release and lovastatin
    • Hunninghake DB, McGovern ME, Koren M et al. A dose-ranging study of a new, once-daily, dual-component drug product containing niacin extended-release and lovastatin. Clin Cardiol 2003; 26: 112-8.
    • (2003) Clin Cardiol , vol.26 , pp. 112-118
    • Hunninghake, D.B.1    McGovern, M.E.2    Koren, M.3
  • 44
    • 0038201868 scopus 로고    scopus 로고
    • Effects of extended-release niacin on lipoprotein subclass distribution
    • Morgan JM, Capuzzi DM, Baksh RI et al. Effects of extended-release niacin on lipoprotein subclass distribution. Am J Cardiol 2003; 91: 1432-6.
    • (2003) Am J Cardiol , vol.91 , pp. 1432-1436
    • Morgan, J.M.1    Capuzzi, D.M.2    Baksh, R.I.3
  • 45
    • 3242717055 scopus 로고    scopus 로고
    • Safety and compliance with once-daily niacin extended-release/lovastatin as initial therapy in the Impact of Medical Subspecialty on Patient Compliance to Treatment (IMPACT) study
    • Impact of Medical Subspecialty on Patient Compliance to Treatment Study Group
    • Rubenfire M, Impact of Medical Subspecialty on Patient Compliance to Treatment Study Group. Safety and compliance with once-daily niacin extended-release/lovastatin as initial therapy in the Impact of Medical Subspecialty on Patient Compliance to Treatment (IMPACT) study. Am J Cardiol 2004; 94: 306-11.
    • (2004) Am J Cardiol , vol.94 , pp. 306-311
    • Rubenfire, M.1
  • 46
    • 2442520797 scopus 로고    scopus 로고
    • Efficacy of extended-release niacin with lovastatin for hypercholesterolemia: Assessing all reasonable doses with innovative surface graph analysis
    • Insull W Jr, McGovern ME, Schrott H et al. Efficacy of extended-release niacin with lovastatin for hypercholesterolemia: Assessing all reasonable doses with innovative surface graph analysis. Arch Intern Med 2004; 164: 1121-7.
    • (2004) Arch Intern Med , vol.164 , pp. 1121-1127
    • Insull Jr., W.1    McGovern, M.E.2    Schrott, H.3
  • 47
    • 0842324675 scopus 로고    scopus 로고
    • Safety and tolerability of simvastatin plus niacin in patients with coronary artery disease and low high-density lipoprotein cholesterol (The HDL Atherosclerosis Treatment Study)
    • Zhao XQ, Morse JS, Dowdy AA et al. Safety and tolerability of simvastatin plus niacin in patients with coronary artery disease and low high-density lipoprotein cholesterol (The HDL Atherosclerosis Treatment Study). Am J Cardiol 2004; 93: 307-12.
    • (2004) Am J Cardiol , vol.93 , pp. 307-312
    • Zhao, X.Q.1    Morse, J.S.2    Dowdy, A.A.3
  • 48
    • 0036190893 scopus 로고    scopus 로고
    • Effect of very-low-dose niacin on high-density lipoprotein in patients undergoing long-term statin therapy
    • Wink J, Giacoppe G, King J. Effect of very-low-dose niacin on high-density lipoprotein in patients undergoing long-term statin therapy. Am Heart J 2002; 143: 514-8.
    • (2002) Am Heart J , vol.143 , pp. 514-518
    • Wink, J.1    Giacoppe, G.2    King, J.3
  • 49
    • 19944426989 scopus 로고    scopus 로고
    • A randomized trial of a strategy for increasing high-density lipoprotein cholesterol levels: Effects on progression of coronary heart disease and clinical events
    • Whitney EJ, Krasuski RA, Personius BE et al. A randomized trial of a strategy for increasing high-density lipoprotein cholesterol levels: effects on progression of coronary heart disease and clinical events. Ann Intern Med 2005; 142: 95-104.
    • (2005) Ann Intern Med , vol.142 , pp. 95-104
    • Whitney, E.J.1    Krasuski, R.A.2    Personius, B.E.3
  • 50
    • 10044281651 scopus 로고    scopus 로고
    • Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol (ARBITER) 2
    • Taylor AJ, Sullenberger LE, Lee HJ et al. Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol (ARBITER) 2. Circulation 2004; 110: 3512-7.
    • (2004) Circulation , vol.110 , pp. 3512-3517
    • Taylor, A.J.1    Sullenberger, L.E.2    Lee, H.J.3
  • 51
    • 0025183769 scopus 로고
    • Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B
    • Brown G, Albers JJ, Fisher LD et al. Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B. N Engl J Med 1990; 323: 1289-98.
    • (1990) N Engl J Med , vol.323 , pp. 1289-1298
    • Brown, G.1    Albers, J.J.2    Fisher, L.D.3
  • 52
    • 0038201862 scopus 로고    scopus 로고
    • Effectiveness of aggressive management of dyslipidemia in a collaborative-care practice model
    • Ryan MJ Jr, Gibson J, Simmons P, Stanek E. Effectiveness of aggressive management of dyslipidemia in a collaborative-care practice model. Am J Cardiol 2003; 91: 1427-31.
    • (2003) Am J Cardiol , vol.91 , pp. 1427-1431
    • Ryan Jr., M.J.1    Gibson, J.2    Simmons, P.3    Stanek, E.4
  • 53
    • 0035969564 scopus 로고    scopus 로고
    • Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease
    • Brown BG, Zhao XQ, Chait A. Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease. N Engl J Med 2001; 345: 1583-92.
    • (2001) N Engl J Med , vol.345 , pp. 1583-1592
    • Brown, B.G.1    Zhao, X.Q.2    Chait, A.3
  • 54
    • 0034644442 scopus 로고    scopus 로고
    • Effect of niacin on lipid and lipoprotein levels and glycemic control in patients with diabetes and peripheral arterial disease: The ADMIT study: A randomized trial. Arterial Dis Multiple Intervention Trial
    • Elam MB, Hunninghake DB, Davis KB et al. Effect of niacin on lipid and lipoprotein levels and glycemic control in patients with diabetes and peripheral Arterial disease: The ADMIT study: a randomized trial. Arterial Dis Multiple Intervention Trial. JAMA 2000; 284: 1263-70.
    • (2000) JAMA , vol.284 , pp. 1263-1270
    • Elam, M.B.1    Hunninghake, D.B.2    Davis, K.B.3
  • 55
    • 0022397947 scopus 로고
    • Improvement of the nicotinic acid test in the diagnosis of Gilbert's syndrome by pretreatment with indomethacin
    • Gentile S, Rubba P, Persico M et al. Improvement of the nicotinic acid test in the diagnosis of Gilbert's syndrome by pretreatment with indomethacin. Hepatogastroenterology 1985; 32: 267-9.
    • (1985) Hepatogastroenterologyy , vol.32 , pp. 267-269
    • Gentile, S.1    Rubba, P.2    Persico, M.3
  • 56
    • 0025347734 scopus 로고
    • Objective assessment of topical corticosteroids and non-steroidal anti-inflammatory drugs in methyl-nicotinate-induced skin inflammation
    • Duteil L, Queille C, Poncet M et al. Objective assessment of topical corticosteroids and non-steroidal anti-inflammatory drugs in methyl-nicotinate-induced skin inflammation. Clin Exp Dermatol 1990; 15: 195-9.
    • (1990) Clin Exp Dermatol , vol.15 , pp. 195-199
    • Duteil, L.1    Queille, C.2    Poncet, M.3
  • 57
    • 0036018540 scopus 로고    scopus 로고
    • Opposite effects of nicotinic acid and pyridoxine on systemic prostacyclin, thromboxane and leukotriene production in man
    • Saareks V, Ylitalo P, Mucha I, Riutta A. Opposite effects of nicotinic acid and pyridoxine on systemic prostacyclin, thromboxane and leukotriene production in man. Pharmacol Toxicol 2002; 90: 338-42.
    • (2002) Pharmacol Toxicol , vol.90 , pp. 338-342
    • Saareks, V.1    Ylitalo, P.2    Mucha, I.3    Riutta, A.4
  • 58
    • 0023930868 scopus 로고
    • Report of the national education program expert panel on detection, evaluation and treatment of high blood cholesterol in adults
    • Cholesterol Adult Treatment Panel
    • Cholesterol Adult Treatment Panel. Report of the national education program expert panel on detection, evaluation and treatment of high blood cholesterol in adults. Arch Intern Med 1988; 148: 36-9.
    • (1988) Arch Intern Med , vol.148 , pp. 36-39
  • 59
    • 0016630250 scopus 로고
    • Clofibrate and niacin in coronary heart disease
    • Coronary Drug Research Group
    • Coronary Drug Research Group. Clofibrate and niacin in coronary heart disease. JAMA 1975; 231: 360-81.
    • (1975) JAMA , vol.231 , pp. 360-381
  • 60
    • 0023733072 scopus 로고
    • Effect of low-dose niacin on high-density lipoprotein cholesterol and total cholesterol/high-density lipoprotein cholesterol ratio
    • Luria MH. Effect of low-dose niacin on high-density lipoprotein cholesterol and total cholesterol/high-density lipoprotein cholesterol ratio. Arch Intern Med 1988; 148: 2493-5.
    • (1988) Arch Intern Med , vol.148 , pp. 2493-2495
    • Luria, M.H.1
  • 61
    • 0027407445 scopus 로고
    • Evaluation of the effectiveness of lipid-lowering therapy (bile acid sequestrants, niacin, psyllium and lovastatin) for treating hypercholesterolemia in veterans
    • Schectman G, Hiatt J, Hartz A. Evaluation of the effectiveness of lipid-lowering therapy (bile acid sequestrants, niacin, psyllium and lovastatin) for treating hypercholesterolemia in veterans. Am J Cardiol 1993; 71: 759-65.
    • (1993) Am J Cardiol , vol.71 , pp. 759-765
    • Schectman, G.1    Hiatt, J.2    Hartz, A.3
  • 62
    • 0027963479 scopus 로고
    • Comparative effects of lovastatin and niacin in primary hypercholesterolemia. A prospective trial
    • Illingworth DR, Stein EA, Mitchel YB et al. Comparative effects of lovastatin and niacin in primary hypercholesterolemia. A prospective trial. Arch Intern Med 1994; 154: 1586-95.
    • (1994) Arch Intern Med , vol.154 , pp. 1586-1595
    • Illingworth, D.R.1    Stein, E.A.2    Mitchel, Y.B.3
  • 63
    • 0028057319 scopus 로고
    • A comparison of the efficacy and toxic effects of sustained- vs immediate-release niacin in hypercholesterolemic patients
    • McKenney JM, Proctor JD, Harris S, Chinchili VM. A comparison of the efficacy and toxic effects of sustained- vs immediate-release niacin in hypercholesterolemic patients. JAMA 1994; 271: 672-7.
    • (1994) JAMA , vol.271 , pp. 672-677
    • McKenney, J.M.1    Proctor, J.D.2    Harris, S.3    Chinchili, V.M.4
  • 64
    • 0029924834 scopus 로고    scopus 로고
    • Effectiveness of low-dose crystalline nicotinic acid in men with low high-density lipoprotein cholesterol levels
    • Martin-Jadraque R, Tato F, Mostaza JM et al. Effectiveness of low-dose crystalline nicotinic acid in men with low high-density lipoprotein cholesterol levels. Arch Intern Med 1996; 156: 1081-8.
    • (1996) Arch Intern Med , vol.156 , pp. 1081-1088
    • Martin-Jadraque, R.1    Tato, F.2    Mostaza, J.M.3
  • 65
    • 33744546252 scopus 로고    scopus 로고
    • US prescribing information on line. (accessed on October 10)
    • US prescribing information on line. http://www.niaspan.com (accessed on October 10 2005).
    • (2005)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.