Effects of repeated in vivo inhalant nitrite exposure on gene expression in mouse liver and lungs

Nitric Oxide - Biology and Chemistry

Volumn 14, Issue 4, 2006, Pages 279-289

  Tran, Doanh C ^a   Brazeau, Daniel A ^a   Nickerson, Peter A ^b   Fung, Ho Leung ^a  

^a UNIVERSITY AT BUFFALO   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

Author keywords

eNOS; Gene array; Isobutyl nitrite; NO donor; VEGF

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; FIBROBLAST GROWTH FACTOR 1; FIBROBLAST GROWTH FACTOR 4; HEAT SHOCK PROTEIN 70; HEME OXYGENASE 1; ISOBUTYL NITRITE; LIVER PROTEIN; MESSENGER RNA; NITRIC OXIDE DONOR; SMAD7 PROTEIN; THROMBOCYTE FACTOR 4; VASCULOTROPIN; VASCULOTROPIN A; VASCULOTROPIN D;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GENETICS; CONTROLLED STUDY; DNA MICROARRAY; DRUG ABUSE; ENVIRONMENTAL EXPOSURE; FOLLOW UP; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; LIVER; LIVER CELL; LIVER SLICE; LUNG; MALE; MOLECULAR WEIGHT; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STATISTICAL SIGNIFICANCE; UNINDEXED SEQUENCE; UPREGULATION;

ADMINISTRATION, INHALATION; ANIMALS; GENE EXPRESSION; LIVER; LUNG; MICE; MICE, INBRED C57BL; NITRIC OXIDE DONORS; NITRIC OXIDE SYNTHASE; NITRITES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 33744508791     PISSN: 10898603     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.niox.2005.09.010     Document Type: Article

References (52)

1. Brouette T., and Anton R. Clinical review of inhalants. Am. J. Addict. 10 (2001) 79-94
2. Haverkos H.W. Nitrite inhalant abuse and AIDS-related Kaposi's sarcoma. J. Acquir. Immune. Defic. Syndr. 3 (1990) S47-S50
3. Marmor M., Friedman-Kien A.E., Laubenstein L., Byrum R.D., William D.C., D'Onofrio S., and Dubin N. Risk factors for Kaposi's sarcoma in homosexual men. Lancet 1 (1982) 1083-1087
4. Soderberg L.S. Increased tumor growth in mice exposed to inhaled isobutyl nitrite. Toxicol. Lett. 104 (1999) 35-41
5. Lotzova E., Savary C.A., Hersh E.M., Khan A.A., and Rosenblum M. Depression of murine natural killer cell cytotoxicity by isobutyl nitrite. Cancer Immunol. Immunother. 17 (1984) 130-134
6. Soderberg L.S., and Barnett J.B. Inhalation exposure to isobutyl nitrite inhibits macrophage tumoricidal activity and modulates inducible nitric oxide. J. Leukoc. Biol. 57 (1995) 135-140
7. Soderberg L.S., Flick J.T., and Barnett J.B. Leukopenia and altered hematopoietic activity in mice exposed to the abused inhalant, isobutyl nitrite. Exp. Hematol. 24 (1996) 848-853
8. Soderberg L.S., Chang L.W., and Barnett J.B. Elevated TNF-alpha and inducible nitric oxide production by alveolar macrophages after exposure to a nitrite inhalant. J. Leukoc. Biol. 60 (1996) 459-464
9. Tran D.C., Yeh K.-C., Brazeau D.A., and Fung H.-L. Inhalant nitrite exposure alters mouse hepatic angiogenic gene expression. Biochem. Biophys. Res. Commun. 310 (2003) 439-445
10. Weindel K., Marme D., and Weich H.A. AIDS-associated Kaposi's sarcoma cells in culture express vascular endothelial growth factor. Biochem. Biophys. Res. Commun. 183 (1992) 1167-1174
11. Samaniego F., Young D., Grimes C., Prospero V., Christofidou-Solomidou M., DeLisser H.M., Prakash O., Sahin A.A., and Wang S. Vascular endothelial growth factor and Kaposi's sarcoma cells in human skin grafts. Cell Growth Differ. 13 (2002) 387-395
12. Stallone G., Schena A., Infante B., Di Paolo S., Loverre A., Maggio G., Ranieri E., Gesualdo L., Schena F.P., and Grandaliano G. Sirolimus for Kaposi's sarcoma in renal-transplant recipients. N. Engl. J. Med. 352 (2005) 1317-1323
13. Soderberg L.S., and Barnett J.B. Exposure to inhaled isobutyl nitrite reduces T cell blastogenesis and antibody responsiveness. Fundam. Appl. Toxicol. 17 (1991) 821-824
14. Kowaluk E.A., and Fung H.L. Vascular nitric oxide-generating activities for organic nitrites and organic nitrates are distinct. J. Pharmacol. Exp. Ther. 259 (1991) 519-525
15. Wang E.Q., Lee W.I., Brazeau D., and Fung H.L. cDNA microarray analysis of vascular gene expression after nitric oxide donor infusions in rats: implications for nitrate tolerance mechanisms. Aaps Pharmsci. 4 (2002) E10
16. Benoit H., Jordan M., Wagner H., and Wagner P.D. Effect of NO, vasodilator prostaglandins, and adenosine on skeletal muscle angiogenic growth factor gene expression. J. Appl. Physiol. 86 (1999) 1513-1518
17. Yuhanna I.S., MacRitchie A.N., Lantin-Hermoso R.L., Wells L.B., and Shaul P.W. Nitric oxide (NO) upregulates NO synthase expression in fetal intrapulmonary artery endothelial cells. Am. J. Respir. Cell Mol. Biol. 21 (1999) 629-636
18. Idriss S.D., Gudi T., Casteel D.E., Kharitonov V.G., Pilz R.B., and Boss G.R. Nitric oxide regulation of gene transcription via soluble guanylate cyclase and type I cGMP-dependent protein kinase. J. Biol. Chem. 274 (1999) 9489-9493
19. Jozkowicz A., Cooke J.P., Guevara I., Huk I., Funovics P., Pachinger O., Weidinger F., and Dulak J. Genetic augmentation of nitric oxide synthase increases the vascular generation of VEGF. Cardiovasc. Res. 51 (2001) 773-783
20. Kimura H., Ogura T., Kurashima Y., Weisz A., and Esumi H. Effects of nitric oxide donors on vascular endothelial growth factor gene induction. Biochem. Biophys. Res. Commun. 296 (2002) 976-982
21. Dulak J., and Jozkowicz A. Regulation of vascular endothelial growth factor synthesis by nitric oxide: facts and controversies. Antioxid Redox Signal 5 (2003) 123-132
22. Kielbasa W., and Fung H.L. Nitrite inhalation in rats elevates tissue NOS III expression and alters tyrosine nitration and phosphorylation. Biochem. Biophys. Res. Commun. 275 (2000) 335-342
23. Kielbasa W.B., Bauer J.A., and Fung H.L. Analysis of isobutyl nitrite inhalant in rat and human blood: application for pharmacokinetic investigations. J. Chromatogr. B: Biomed. Sci. Appl. 734 (1999) 83-89
24. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72 (1976) 248-254
25. Frank S., Stallmeyer B., Kampfer H., Kolb N., and Pfeilschifter J. Nitric oxide triggers enhanced induction of vascular endothelial growth factor expression in cultured keratinocytes (HaCaT) and during cutaneous wound repair. FASEB J. 13 (1999) 2002-2014
26. Tran D.C., Brazeau D.A., and Fung H.L. Determination of nitric oxide-donor effects on tissue gene expression in vivo using low-density gene arrays. Methods Enzymol. 396 (2005) 387-395
27. D.M. Ornitz, N. Itoh, Fibroblast growth factors, Genome Biol. Rev. 2 (2001) 3005.1-3005.12.
28. Xue L., and Greisler H.P. Angiogenic effect of fibroblast growth factor-1 and vascular endothelial growth factor and their synergism in a novel in vitro quantitative fibrin-based 3-dimensional angiogenesis system. Surgery 132 (2002) 259-267
29. Jouanneau J., Moens G., Montesano R., and Thiery J.P. FGF-1 but not FGF-4 secreted by carcinoma cells promotes in vitro and in vivo angiogenesis and rapid tumor proliferation. Growth Factors 12 (1995) 37-47
30. Thompson J.A., Anderson K.D., DiPietro J.M., Zwiebel J.A., Zametta M., Anderson W.F., and Maciag T. Site-directed neovessel formation in vivo. Science 241 (1988) 1349-1352
31. Vickers S.M., MacMillan-Crow L., Huang Z.-Q., and Thompson J.A. Acidic fibroblast growth factor (FGF-1) signaling inhibits peroxynitrite-induced cell death during pancreatic tumorigenesis. Free Radic. Biol. and Med. 30 (2001) 957-966
32. Opalenik S.R., Shin J.T., Wehby J.N., Mahesh V.K., and Thompson J.A. The HIV-1 TAT protein induces the expression and extracellular appearance of acidic fibroblast growth factor. J. Biol. Chem. 270 (1995) 17457-17467
33. Ensoli B., Nakamura S., Salahuddin S.Z., Biberfeld P., Larsson L., Beaver B., Wong-Staal F., and Gallo R.C. AIDS-Kaposi's sarcoma-derived cells express cytokines with autocrine and paracrine growth effects. Science 243 (1989) 223-226
34. Yamamoto H., Ochiya T., Takahama Y., Ishii Y., Osumi N., Sakamoto H., and Terada M. Detection of spatial localization of Hst-1/Fgf-4 gene expression in brain and testis from adult mice. Oncogene 19 (2000) 3805-3810
35. Yoshida T., Ishimaru K., Sakamoto H., Yokota J., Hirohashi S., Igarashi K., Sudo K., and Terada M. Angiogenic activity of the recombinant hst-1 protein. Cancer Lett. 83 (1994) 261-268
36. Dell'Era P., Belleri M., Stabile H., Massardi M.L., Ribatti D., and Presta M. Paracrine and autocrine effects of fibroblast growth factor-4 in endothelial cells. Oncogene 20 (2001) 2655-2663
37. Rissanen T.T., Markkanen J.E., Arve K., Rutanen J., Kettunen M.I., Vajanto I., Jauhiainen S., Cashion L., Gruchala M., Narvanen O., Taipale P., Kauppinen R.A., Rubanyi G.M., and Yla-Herttuala S. Fibroblast growth factor 4 induces vascular permeability, angiogenesis and arteriogenesis in a rabbit hindlimb ischemia model. FASEB J. 17 (2003) 100-102
38. Sikorski E.M., Hock T., Hill-Kapturczak N., and Agarwal A. The story so far: molecular regulation of the heme oxygenase-1 gene in renal injury. Am. J. Physiol. Renal Physiol. 286 (2004) F425-F441
39. Fernandez M., and Bonkovsky H.L. Vascular endothelial growth factor increases heme oxygenase-1 protein expression in the chick embryo chorioallantoic membrane. Br. J. Pharmacol. 139 (2003) 634-640
40. Bussolati B., Ahmed A., Pemberton H., Landis R.C., Di Carlo F., Haskard D.O., and Mason J.C. Bifunctional role for VEGF-induced heme oxygenase-1 in vivo: induction of angiogenesis and inhibition of leukocytic infiltration. Blood 103 (2004) 761-766
41. Kiang J.G., and Tsokos G.C. Heat shock protein 70 kDa: molecular biology, biochemistry, and physiology. Pharmacol. Therap. 80 (1998) 183-201
42. Suzuki E., Kageyama H., Nakaki T., Kanba S., Inoue S., and Miyaoka H. Nitric oxide induced heat shock protein 70 mRNA in rat hypothalamus during acute restraint stress under sucrose diet. Cell. Mol. Neurobiol. 23 (2003) 907-915
43. M.J. Hu, Y. Liu, C.G. Deng, Y.Q. Chang, J.N. Wang, Y.Z. Dong, Heat shock protein 70 expression in the brain of rats with cerebral infarction after receiving vascular endothelial growth factor 165 gene therapy, Di Yi Jun Yi Da Xue Xue Bao 23 (2003) 720-722.
44. Garrido C., Schmitt E., Cande C., Vahsen N., Parcellier A., and Kroemer G. HSP27 and HSP70: potentially oncogenic apoptosis inhibitors. Cell Cycle 2 (2003) 579-584
45. Bikfalvi A. Platelet factor 4: an inhibitor of angiogenesis. Semin. Thromb. Hemost. 30 (2004) 379-385
46. Maione T.E., Gray G.S., Hunt A.J., and Sharpe R.J. Inhibition of tumor growth in mice by an analogue of platelet factor 4 that lacks affinity for heparin and retains potent angiostatic activity. Cancer Res. 51 (1991) 2077-2083
47. Sharpe R.J., Byers H.R., Scott C.F., Bauer S.I., and Maione T.E. Growth inhibition of murine melanoma and human colon carcinoma by recombinant human platelet factor 4. J. Natl. Cancer Inst. 82 (1990) 848-853
48. Bilezikjian L.M., Corrigan A.Z., Blount A.L., Chen Y., and Vale W.W. Regulation and actions of Smad7 in the modulation of activin, inhibin, and transforming growth factor-beta signaling in anterior pituitary cells. Endocrinology 142 (2001) 1065-1072
49. Massague J., Blain S.W., and Lo R.S. TGFbeta signaling in growth control, cancer, and heritable disorders. Cell 103 (2000) 295-309
50. Nakagawa T., Li J.H., Garcia G., Mu W., Piek E., Bottinger E.P., Chen Y., Zhu H.J., Kang D.H., Schreiner G.F., Lan H.Y., and Johnson R.J. TGF-beta induces proangiogenic and antiangiogenic factors via parallel but distinct Smad pathways. Kidney Int. 66 (2004) 605-613
51. Zhu H.J., Iaria J., and Sizeland A.M. Smad7 differentially regulates transforming growth factor beta-mediated signaling pathways. J. Biol. Chem. 274 (1999) 32258-32264
52. Kielbasa W., and Fung H.L. Pharmacokinetics of a model organic nitrite inhalant and its alcohol metabolite in rats. Drug Metab. Dispos. 28 (2000) 386-391