Primary mediastinal large B-cell lymphoma: A single-center study of clinicopathologic characteristics

International Journal of Hematology

Volumn 83, Issue 4, 2006, Pages 331-336

  Kolonić, Slobodanka Ostojić ^a   Džebro, Sonja ^a   Kušec, Rajko ^a   Planinc Peraica, Ana ^a   Dominis, Mara ^a   Jakšić, Branimir ^a  

^a University of Zagreb   (Croatia)

Author keywords

Clinicopathologic features; Herpesviruses; Primary mediastinal large B cell lymphoma; Prognostic factors

Indexed keywords

CD30 ANTIGEN; CYCLOPHOSPHAMIDE; DAUNORUBICIN; INTERFERON REGULATORY FACTOR 4; LACTATE DEHYDROGENASE; OCTAMER TRANSCRIPTION FACTOR 2; PREDNISONE; PROTEIN BCL 6; TRANSCRIPTION FACTOR PAX5; VINCRISTINE;

ADULT; ADVANCED CANCER; ANTIGEN EXPRESSION; ARTICLE; B CELL LYMPHOMA; CANCER PATIENT; CANCER REGRESSION; CLINICAL ARTICLE; CLINICAL FEATURE; CROATIA; DISEASE COURSE; DRUG EFFICACY; FEMALE; FOLLOW UP; GENE SEQUENCE; HISTOPATHOLOGY; HUMAN; HUMAN HERPESVIRUS 6; HUMAN HERPESVIRUS 8; HUMAN TISSUE; LACTATE DEHYDROGENASE BLOOD LEVEL; MALE; PRIMARY MEDIASTINAL LARGE B CELL LYMPHOMA; PROGNOSIS; PROTEIN EXPRESSION; RETROSPECTIVE STUDY; SYMPTOMATOLOGY; TREATMENT INDICATION; TREATMENT OUTCOME; VIRUS GENOME;

ADULT; AGE FACTORS; ANTIGENS, CD30; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CYCLOPHOSPHAMIDE; DNA-BINDING PROTEINS; DOXORUBICIN; FEMALE; FOLLOW-UP STUDIES; GENE EXPRESSION REGULATION, LEUKEMIC; GENOME, VIRAL; HERPESVIRUS 6, HUMAN; HERPESVIRUS 8, HUMAN; HUMANS; L-LACTATE DEHYDROGENASE; LYMPHOMA, B-CELL; LYMPHOMA, LARGE-CELL; MALE; MEDIASTINAL NEOPLASMS; MIDDLE AGED; PREDNISONE; PROGNOSIS; RETROSPECTIVE STUDIES; ROSEOLOVIRUS INFECTIONS; SEX FACTORS; VINCRISTINE;

EID: 33744507087     PISSN: 09255710     EISSN: None     Source Type: Journal    
DOI: 10.1532/IJH97.E0529     Document Type: Article

References (30)

1. Harris NL, Jaffe ES, Stein H, et al. A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group. Blood. 1994;84:1361-1392.
2. Sekiguchi N, Nishimoto J, Tanimoto K, et al. Primary mediastinal large B-cell lymphoma: a single-institution clinical study in Japan. Int J Hematol. 2004;79:465-471.
3. Andreopoulou H, Pectasides D, Dimopoulos MA. et al. Primary mediastinal large B-cell lymphoma: clinical study of a distinct clinical entity and treatment outcome in 20 patients: review of the literature. Am J Clin Oncol. 2004;27:312-316.
4. Pileri SA, Gaidano G, Zinzani PL, et al. Primary mediastinal B-cell lymphoma: high frequency of BCL-6 mutations and consistent expression of the transcription factors OCT-2, BOB.1, and PU.1 in the absence of immunoglobulins. Am J Pathol. 2003;162:243-253.
5. De Leval L, Ferry JA, Falini B, Shipp M, Harris NL. Expression of bcl-6 and CD10 in primary mediastinal large B-cell lymphoma: evidence for derivation from germinal center B cells?. Am J Surg Pathol. 2001;25:1277-1282.
6. Tsang P, Cesarman E, Chadburn A, Liu YF, Knowles DM. Molecular characterization of primary mediastinal B cell lymphoma. Am J Pathol. 1996;148:2017-2025.
7. Copie-Bergman C, Gaulard P, Mauche-Chretien L, et al. The MAL gene is expressed in primary mediastinal large B-cell lymphoma. Blood. 1999;94:3567-3575.
8. Van Besien K, Kelta M, Bahaguna P. Primary mediastinal B-cell lymphoma: a review of pathology and management. J Clin Oncol. 2001;19:1855-1864.
9. Rosenwald A, Wright G, Leroy K, et al. Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma. J Exp Med. 2003;198:851-862.
10. Abou-Elella AA, Weisenburger DD, Vose JM, et al. Primary mediastinal large B-cell lymphoma: a clinicopathologic study of 43 patients from the Nebraska Lymphoma Study Group. J Clin Oncol. 1999;17:784-790.
11. Dabrowska-Iwanicka A, Borawska A, Federowicz I, et al. Primary mediastinal B-cell lymphoma (PMLCL): treatment outcome of 34 patients treated at Maria Sklodowska-Curie Cancer Centre in Warsaw [abstract]. Ann Oncol. 2005;16(suppl 5):164.
12. Lamarre L, Jacobson JO, Aisenberg AC, Harris NL. Primary large cell lymphoma of the mediastinum: a histologic and immunophenotypic study of 29 cases. Am J Surg Pathol. 1989;13:730-739.
13. Todeschini G, Ambrosetti A, Meneghini V, et al. Mediastinal large B-cell lymphoma with sclerosis: a clinical study of 21 patients. J Clin Oncol. 1990;8:804-808.
14. Cazals-Hatem D, Lepage E, Brice P, et al. Primary mediastinal large B-cell lymphoma: a clinicopathologic study of 141 cases compared with 916 nonmediastinal large B-cell lymphomas. a GELA ("Groupe d'Etude des Lymphomesde l'Adulte") study. Am J Surg Pathol. 1996;20:877-888.
15. Todeschini G, Secchi S, Morra E, et al. Primary mediastinal large B-cell lymphoma (PMLBCL): long-term results from a retrospective multicentre Italian experience in 138 patients treated with CHOP or MACOP-B/VACOP-B. Br J Cancer. 2004;90:372-376.
16. Banks PM, Warnke RA. Mediastinal (thymic) large B-cell lymphoma. In: Jaffe ES, Harris NL, Stein H. Vardiman JW, eds. World Health Organization Classification of Tumours. Pathology & Genetics: Tumours of Haematopoietic and Lymphoid Tissue. Lyon, France: IARC Press; 2001:175-476.
17. Daibata M, Komatsu T, Taguchi H. Human herpesviruses in primary ocular lymphoma. Leuk Lymphoma. 2000;37:361-365.
18. Carbone PP, Kaplan HS, Musshoff K, Smithers DW, Tubiana M. Report of the Committee on Hodgkin's Disease Staging Classification. Cancer Res. 1971;31:1860-1861.
19. The International Non-Hodgkin's Lymphoma Prognostic Factors Project. A predictive model for aggressive non-Hodgkin's lymphoma. N Engl J Med. 1993;329:987-994.
20. Cheson BD, Horning SJ, Coiffier B, et al. Report of an international workshop to standardize response criteria for non-Hodgkin's lymphomas. NCI Sponsored International Working Group. J Clin Oncol. 1999;17:1244-1254.
21. Falini B, Venturi S, Martelli M, et al. Mediastinal large B-cell lymphoma: clinical and immunohistologic findings in 18 patients treated with different third-generation regimens. Br J Haematol. 1995;89:780-789.
22. Anderson JR, Armitage JO, Weisenburger DD. Epidemiology of the non-Hodgkin's lymphomas: distributions of the major subtypes differ by geographic locations. Non-Hodgkin's Lymphoma Classification Project. Ann Oncol. 1998;9:717-720.
23. Lazzarino M, Orlandi E, Paulli M, et al. Primary mediastinal B-cell lymphoma with sclerosis: an aggressive tumor with distinctive clinical and pathologic features. J Clin Oncol. 1993;11:2306-2313.
24. Higgins JP, Warnke RA. CD30 expression is common in mediastinal large B-cell lymphoma. Am J Clin Pathol. 1999;112:241-247.
25. Barrans SL, O'Connor SJ, Evans PA, et al. Rearrangement of the BCL6 locus at 3q27 is an independent poor prognostic factor in nodal diffuse large B-cell lymphoma. Br J Haematol. 2002;1:17: 322-332.
26. Savage KJ, Al-Rajhi N, Voss N, et al. Outcome of primary mediastinal large B-cell lymphoma in a single institution: the British Columbia experience [abstract]. Ann Oncol. 2005;16(suppl 5):56.
27. Bieri S, Roggero E, Zucca E, et al. Primary mediastinal large B-cell lymphoma (PMLCL): the need for prospective controlled clinical trials. Leuk Lymphoma. 1999;35:139-146.
28. Martelli MP, Martelli M, Pescarmona E, et al. MACOP-B and involved field radiation therapy is an effective therapy for primary mediastinal large B-cell lymphoma with sclerosis. Ann Oncol. 1998; 9:1027-1029.
29. Romaguera JE, Rodriguez Diaz-Pavon J, Carias L, et al. Use of the international prognostic index and the tumor score to detect poor-risk patients with primary mediastinal large B-cell lymphoma: a study of 37 previously untreated patients. Leuk Lymphoma. 1998; 28:295-306.
30. Hamlin PA, Portlock CS, Straus DJ, et al. Primary mediastinal large B-cell lymphoma: optimal therapy and prognostic factor analysis in 141 consecutive patients treated at Memorial Sloan Kettering from 1980 to 1999. Br J Haematol. 2005;130:691-699.