The MAL gene is expressed in primary mediastinal large B-cell lymphoma

Blood

Volumn 94, Issue 10, 1999, Pages 3567-3575

  Copie Bergman, Christiane ^b   Gaulard, Philippe ^b   Maouche Chrétien, Leïla ^b   Brière, Josette ^b   Haioun, Corinne ^b   Alonso, Miguel A ^b   Roméo, Paul Henri ^b   Leroy, Karen ^a  

^a HENRI MONDOR HOSPITAL   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; B CELL LYMPHOMA; CLINICAL ARTICLE; FEMALE; GENE EXPRESSION; GENE REARRANGEMENT; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; MEDIASTINUM MASS; MOLECULAR DYNAMICS; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION;

EID: 0033571549     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v94.10.3567.422k06_3567_3575     Document Type: Article

References (43)

1. Harris NL, Jaffe ES, Stein H, Banks PM, Chan JKC, Clearly ML, Delsol G, De Wolf-Peeters C, Falini B, Gatter KC, Grogan TM, Isaacson PG, Knowles DM, Mason DY, Müller-Hermelink HK, Pileri SA, Piris MA, Ralfkiaer E, Warnke RA: A revised European-American classification of lymphoid neoplasms: A proposal from the International Lymphoma Study Group. Blood 84:1361, 1994
2. Engelhard M, Brittinger G, Huhn D, Gerhartz HH, Meusers P, Siegert W, Thiel E, Wilmanns W, Aydemir U, Bierwolf S, Griesser H, Tiemann, Lennert K: Subclassification of diffuse large B-cell lymphomas according to the Kiel classification: Distinction of centroblastic and immunoblastic lymphomas is a significant prognostic risk factor. Blood 89:2291, 1997
3. Bastard C, Deweindt C, Kerckaert JP, Lenormand B, Rossi A, Pezzella F, Fruchart C, Duval C, Monconduit M, Tilly H: LAZ3 rearrangements in non-Hodgkin's lymphoma: Correlation with histology, immunophenotype, karyotype and clinical outcome in 217 patients. Blood 83:2423, 1994
4. Fukuda T, Yoshida T, Okada S, Hatano M, Miki T, Ishibashi K, Okabe S, Koseki H, Hirosawa S, Taniguchi M, Miyasaka N, Tokuhisa T: Disruption of the Bcl6 gene results in an impaired germinal center formation. J Exp Med 186:439, 1997
5. Jacobson J, Wilkes B, Kwaiatkowski D, Medeiros L, Aisenberg A, Harris N: Bcl-2 rearrangements in de novo diffuse large cell lymphoma. Association with distinctive clinical features. Cancer 72:231, 1993
6. Ichikawa A, Kinoshita T, Watanabe T, Kato H, Nagai H, Tsushita K, Saito H, Hotta T: Mutations of the P53 gene as a prognosis factor in agressive B-cell lymphoma. N Engl J Med 337:529, 1997
7. Ladanyi M, Offit K, Jhanwar SC, Filippa DA, Chaganti RSK: MYC rearrangement and translocations involving band 8q24 in diffuse large cell lymphomas. Blood 77:1057, 1991
8. Rao PH, Houldsworth J, Dyomina K, Parsa NZ, Cigudosa JC, Louie DC, Popplewell L, Offit K, Jhanwar SC, Chaganti RSK: Chromosomal and gene amplification in diffuse large B-cell lymphoma. Blood 92:234, 1998
9. Lamarre L, Jacobson JO, Aisenberg AC, Harris NL: Primary large cell lymphoma of the mediastinum: A histologic and immunophenotypic study of 29 cases. Am J Surg Pathol 13:730, 1989
10. Al-Sharabati M, Chittal S, Duga-Neulat I, Laurent G, Mazerolles C, Al-Saati T, Brousset P, Delsol G: Primary mediastinal B-cell lymphoma: A clinicopathologic and immunohistochemical study of 16 cases. Cancer 67:2579, 1991
11. Kanavaros P, Gaulard P, Charlotte F, Martin N, Ducos C, Lebezu M, Mason DY: Discordant expression of immunoglobulin and its associated molecule mb-1/CD79a is frequently found in mediastinal large B cell lymphomas. Am J Pathol 146:735, 1995
12. Cazals-Hatem D, Lepage E, Brice P, Ferrant A, d'Agay MF, Baumelou E, Brière J, Blanc M, Gaulard P, Biron P, Schlaifer D, Diebold J, Audouin J: Primary mediastinal large B-cell lymphoma. A clinicopathologic study of 141 cases compared with 916 nonmediastinal large B-cell lymphomas, a GELA study. Am J Surg Pathol 20:877, 1996
13. Isaacson PG, Norton AJ, Addis BJ: The human thymus contains a novel population of B lymphocytes. Lancet 26:1488, 1987
14. Möller P, Moldenhauer G, Momburg F, Lämmler B, Eberlein-Gonska M, Kiesel S, Dörken B: Mediastinal lymphoma of clear cell type is a tumor corresponding to terminal steps of B cell differentiation. Blood 69:1087, 1987
15. Scarpa A, Borgato L, Chilosi M, Capelli P, Menestrina F, Bonetti F, Zamboni G, Pizzolo G, Hirohashi S, Fiore-Donati L: Evidence of c-myc gene abnormalities in mediastinal large B-cell lymphoma of young adult age. Blood 78:780, 1991
16. Tsang P, Cesarman E, Chadburn A, Liu YF, Knowles DM: Molecular characterization of primary mediastinal B cell lymphoma. Am J Pathol 148:2017, 1996
17. Joos S, Otano-Joos MI, Ziegler S, Brüderlein S, du Manoir S, Bentz M, Möller P, Lichter P: Primary mediastinal (thymic) B-cell lymphoma is characterized by gains of chromosomal material including 9p and amplification of the REL gene. Blood 87:1571, 1996
18. Cordell JL, Falini B, Erber W, Ghosh AK, Abdulaziz Z, MacDonald S, Pulford KAF, Stein H, Mason DY: Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes). J Histochem Cytochem 32:219, 1984
19. Stansfeld AG, Diebold J, Noel H, Kapanci Y, Rilke F, Kelenyi G, Sundstrom C, Lennert K, Van Unnik J, Mioduszewska O, Wright D: Updated Kiel classification for lymphomas. Lancet 1:292, 1988
20. Liang P, Pardee AB: Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. Science 257:967, 1992
21. Alonso MA, Weissman SM: cDNA cloning and sequence of MAL, a hydrophobic protein associated with human T-cell differentiation. Proc Natl Acad Sci USA 84:1997, 1987
22. Sambrook J, Fritsh EF, Maniatis T: Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY, Cold Spring Harbor Laboratory, 1989, p 9.14
23. Rancano C, Rubio T, Correas I, Alonso MA: Genomic structure and subcellular localization of MAL, a human T-cell-specific proteolipid protein. J Biol Chem 269:8159, 1994
24. Martin-Belmonte F, Kremer L, Albar JP, Marzuela M, Alonso M: Expression of the MAL gene in the thyroid: The MAL proteolipid, a component of glycolipid-enriched membranes, is apically distributed in thyroid follicles. Endocrinology 139:2077, 1998
25. Rancano C, Rubio T, Alonso MA: Alternative splicing of human T-cell specific MAL mRNA and its correlation with the exon/intron organization of the gene. Genomics 21:447, 1994
26. Wakeman JA, Heath PR, Pearson RC, Andrews PW: MAL mRNA is induced during the differentiation of human embryonal carcinoma cells into neurons and is also localised within specific regions of the human brain. Differentiation 62:97, 1998
27. Alonso MA, Barton DE, Francke U: Assignment of the T-cell differentiation gene MAL to human chromosome 2, region cen-q13. Immunogenetics 27:91, 1988
28. Zacchetti D, Peränen J, Murata M, Fiedler K, Simons K: VIP/MAL, a proteolipid in apical transport vesicles. FEBS Lett 377:465, 1995
29. Millan J, Puertollano R, Fan Li, Rancano C, Alonso MA: The Mal proteolipid is a component of the detergent-insoluble membrane subdomains of human T-lymphocytes. Biochem J 321:247, 1997
30. Simons K, Ikonen E: Functional rafts in cell membranes. Nature 387:569, 1997
31. Xavier R, Brennan T, Li Q, McCormack C, Seed B: Membrane compartmentation is required for efficient T cell activation. Immunity 8:723, 1998
32. Viola A, Schroeder S, Sakakibara Y, Lanzavecchia A: T lymphocyte costimulation mediated by reorganization of membrane microdomains. Science 283:680S, 1999
33. Iiangumaran S, Briol A, Hoessli DC: CD44 selectively associates with active Src family protein tyrosine kinases Lck and Fyn in glycosphingolipid-rich plasma membrane domains of human peripheral blood lymphocytes. Blood 91:3901, 1998
34. Parolini I, Sargiacomo M, Lisanti MP, Peschle C: Signal transduction and glycophosphatidylinositol-linked proteins (LYN, LCK, CD4, CD45, G proteins, and CD55) selectively localize in triton-insoluble plasma membrane domains of human leukemic cell lines and normal granulocytes. Blood 87:3783, 1996
35. Puertollano R, Li S, Lisanti MP, Alonso MA: Recombinant expression of the MAL proteolipid, a component of glycolipid-enriched membrane microdomains, induces the formation of vesicular structures in insect cells. J Biol Chem 272:18311, 1997
36. Puertollano R, Martin-Belmonte F, Millan J, del Carmen de Marco M, Albar JP, Kremer L, Alonso MA: The MAL proteolipid is necessary for normal apical transport and accurate sorting of the influenza virus hemagglutinin in Madin-Darby canine kidney cells. J Cell Biol 145:141, 1999
37. Millan J, Alonso MA: MAL, a novel integral membrane protein of human T lymphocytes, associates with glycosylphosphatidylinositol-anchored proteins and Src-like tyrosine kinases. Eur J Immunol 28:3675, 1998
38. Koleske AJ, Baltimore D, Lisanti MP: Reduction of caveolin and caveolae in oncogenically transformed cells. Proc Natl Acad Sci USA 92:1381, 1995
39. Engelman JA, Wykoff CC, Yasuhara S, Song KS, Okamoto T, Lisanti MP: Recombinant expression of caveolin-1 in oncogenically transformed cells abrogates anchorage-independent growth. J Biol Chem 26:16374, 1997
40. Nasu Y, Timme TL, Yang G, Bangma CH, Li L, Ren C, Hee Park S, Deleon M, Wang J, Thompson TC: Suppression of caveolin expression induces androgen sensitivity in metastatic androgen-insensitive mouse prostate cancer cells. Nat Med 4:1062, 1998
41. Lee SW, Reimer CL, Oh P, Campbell DB, Schnitzer JE: Tumor cell growth inhibition by caveolin re-expression in human breast cancer cells. Oncogene 16:1391, 1998
42. Galbiati F, Volonté D, Engelman JA, Watanabe G, Burk R, Pestell RG, Lisanti MP: Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAPkinase cascade. EMBO J 17:6633, 1998
43. Wary KK, Mariotti A, Zurzolo C, Giancotti FG: A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth. Cell 94:625, 1998