Effect of vitamin E and C supplementation combined with oral antidiabetic therapy on the endothelial dysfunction in the neonatally streptozotocin injected diabetic rat+

Diabetes/Metabolism Research and Reviews

Volumn 22, Issue 3, 2006, Pages 190-197

  Alper, Gülinnaz ^a   Olukman, Murat ^a   Irer, Seda ^a   Çaǧlayan, Osman ^b   Duman, Erdal ^a   Yilmaz, Candeǧer ^a   Ülker, Sibel ^a  

^a EGE UNIVERSITY   (Turkey)

^b KIRIKKALE UNIVERSITY   (Turkey)

Author keywords

Diabetes mellitus; Endothelium dependent relaxation; Gliclazide; Oxidative stress; Vitamins

Indexed keywords

ACETYLCHOLINE; ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; GLICLAZIDE; GLUCOSE; HEMOGLOBIN A1C; INSULIN; MALONALDEHYDE; NITROPRUSSIDE SODIUM; ORAL ANTIDIABETIC AGENT; RETINOL; STREPTOZOCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST FEEDING; CONTROLLED STUDY; DISEASE MODEL; DRUG CONTRAINDICATION; DRUG EFFICACY; ENDOTHELIAL DYSFUNCTION; HYPERGLYCEMIA; NEWBORN; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES; THORACIC AORTA; TREATMENT OUTCOME; VASCULAR ENDOTHELIUM; VASCULAR RING; VASODILATATION; VITAMIN SUPPLEMENTATION; WEIGHT REDUCTION;

ACETYLCHOLINE; ADMINISTRATION, ORAL; ANIMALS; ANIMALS, NEWBORN; ANTIOXIDANTS; ASCORBIC ACID; DIABETES MELLITUS, EXPERIMENTAL; DIETARY SUPPLEMENTS; DISEASE MODELS, ANIMAL; ENDOTHELIUM, VASCULAR; HEMOGLOBIN A, GLYCOSYLATED; HYPOGLYCEMIC AGENTS; MALONDIALDEHYDE; NITROPRUSSIDE; RATS; STREPTOZOCIN; VASODILATION; VITAMIN E;

EID: 33744472784     PISSN: 15207552     EISSN: 15207560     Source Type: Journal    
DOI: 10.1002/dmrr.586     Document Type: Article

References (47)

1. Stern MP. Diabetes and cardiovascular disease. The "common soil" hypothesis. Diabetes 1995; 44: 369-374.
2. Meraji S, Jayakody L, Senaratne PJ, Thomson ABR, Kappagoda T. Endothelium-dependent relaxation in aorta of BB rat. Diabetes 1987; 36: 978-981.
3. Mayhan WG. Impairment of endothelium-dependent dilation of cerebral arterioles during diabetes mellitus. Am J Physiol 1989; 256: H621-H625.
4. Johnstone MT, Creager SJ, Scales KM, Cusco JA, Lee BK, Creager MA. Impaired endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus. Circulation 1993; 88: 2510-2516.
5. McVeigh GE, Brennan GM, Johnston GD. et al. Impaired endothelium-dependent and independent vasodilation in patients with type 2 (non-insulin dependent) diabetes mellitus. Diabetologia 1992; 35: 771-776.
6. Bohlen HG, Lash JM. Topical hyperglycemia rapidly suppresses EDRF-mediated vasodilation of normal rat arterioles. Am J Physiol 1993; 265: H219-H225.
7. Graier WF, Posch K, Fleischhacker E, Wascher TC, Kostner GM. Increased superoxide formation in endothelial cells during hyperglycemia. Diabetes Res Clin Pract 1999; 45: 153-160.
8. Langenstroer P, Pieper GM. Regulation of spontaneous EDRF release in diabetic rat aorta by oxygen free radicals. Am J Physiol 1992; 263: H257-H262.
9. Deiderich D, Skopec J, Diederich A, Dai F. Endothelial dysfunction in mesenteric resistance arteries of diabetic rats: role of free radicals. Am J Physiol 1994; 226: H1153-H1161.
10. Marfella R, Verrazzo G, Acampora R. et al. Glutathione reverses systemic hemodynamic changes by acute hyperglycemia in healthy subjects. Am J Physiol 1995; 268: E1167-H1173.
11. Ting HH, Timimi FK, Boles KS, Creager SJ, Ganz P, Creager MA. Vitamin C improves endothelium-dependent vasodilation in patients with non-insulin-dependent diabetes mellitus. J Clin Invest 1996; 97: 22-28.
12. Bayraktutan U. Free radicals, diabetes and endothelial dysfunction. Diabetes Obes Metab 2002; 4: 224-238.
13. Ülker S, McMaster D, McKeown PP, Bayraktutan U. Antioxidant vitamins C and E ameliorate hyperglycemia-induced oxidative stress in coronary endothelial cells. Diabetes Obes Metab 2004; 6: 442-451.
14. Haidara M, Khloussy H, Ammar H, Aal Kassem LA. Impact of α-tocopherol and vitamin C on endothelial markers in rats with streptozotocin-induced diabetes. Med Sci Monit 2004; 10: BR41-BR46.
15. Timimi FK, Ting HH, Haley EA, Roddy M, Ganz P, Creager MA. Vitamin C improves endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus. J Am Coll Cardiol 1998; 31: 552-557.
16. Çinar MG, Ülker S, Alper G, Evinç A. Effect of dietary vitamin E supplementation on vascular reactivity of the thoracic aorta in streptozotocin-diabetic rats. Pharmacology 2001; 62: 56-64.
17. Dhein S, Kabat A, Olbrich A, Rösen P, Schröder H, Mohr FW. Effect of chronic treatment with vitamin E on endothelial dysfunction in a type I in vivo diabetes mellitus model and in vitro. J Pharmacol Exp Ther 2003; 305: 114-122.
18. Regensteiner JG, Popylisen S, Bauer TA. et al. Oral L-arginine and vitamins E and C improve endothelial function in women with type 2 diabetes. Vasc Med 2003; 8: 169-175.
19. Beckman JA, Goldfine AB, Gordon MB, Garrett LA, Keaney JF Jr, Creager MA. Oral antioxidant therapy improves endothelial function in type 1 but not type 2 diabetes mellitus. Am J Physiol Heart Circ Physiol 2003; 285: H2392-H2398.
20. Skyrme-Jones RA, O'Brien RC, Berry KL, Meredith IT. Vitamin E supplementation improves endothelial function in type 1 diabetes mellitus: a randomized, placebo-controlled study. J Am Coll Cardiol 2000; 36: 94-102.
21. Gazis A, White DJ, Page SR, Cockcroft JR. Effect of oral vitamin E (alpha-tocopherol) supplementation on vascular endothelial function in type 2 diabetes mellitus. Diabet Med 1999; 16: 304-311.
22. Tuzun S, Girgin FK, Sozmen EY, Mantes G, Ersoz B. Antioxidant status in experimental type 2 diabetes mellitus: effects of glibencamide and glipizide on various rat tissues. Exp Toxicol Pathol 1999; 51(4-5): 436-441.
23. Portha B, Blondel O, Serrada P. et al. The rat models of non-insulin dependent diabetes induced by neonatal streptozotocin. Diabete Metab 1989; 15: 61-75.
24. Hakim ZS, Goyal RK. Comparative evaluation of different rat models with co-existing diabetes-mellitus and hypertension. Indian J Physiol Pharmacol 2000; 44: 125-135.
25. Murali B, Goyal RK. Improvement in insulin sensitivity by losartan in non-insulin-dependent diabetic (NIDDM) rats. Pharmacol Res 2001; 44: 385-389.
26. Yagi K. A simple fluorometric assay for lipoperoxide in blood plasma. Biochem Med 1976; 15: 212-216.
27. Armstrong D, Al-Awadi F. Lipid peroxidation and retinopathy in streptozotocin-induced diabetes. Free Radic Biol Med 1991; 11: 433-436.
28. Sim AS, Salonikas C, Naidoo D, Wilcken DEL. Improved method for plasma malondialdehyde measurement by HPLC using methyl malondialdehyde as an internal standard. J Chromatogr B Analyt Technol Biomed Life Sci 2003; 785: 337-344.
29. Claeson K, Thorsen G, Karlberg B. Methyl-malondialdehyde as an internal standard for the determination of malondialdehyde. J Chromatogr B Analyt Technol Biomed Life Sci 2001; 751: 315-323.
30. Arnaud J, Fortis I, Blachier S, Kia D, Favier A. Simultaneous determination of retinol, α-tocopherol and β-carotene in serum by isocratic high-performance liquid chromatography. J Chromatogr 1991; 572: 103-116.
31. De Leenheer AP, De Bevere VO, Cruyl AA, Claeys AE. Determination of serum alpha-tocopherol (vitamin E) by high-performance liquid chromatography. Clin Chem 1978; 24: 585-590.
32. Liau LS, Lee BL, New AL, Ong CN. Determination of plasma ascorbic acid by high-performance liquid chromatography with ultraviolet and electrochemical detection. J Chromatogr 1993; 612: 63-70.
33. Prakasam A, Sethupathy S, Pugalendi KV. Effect of Casearia esculenta root extract on blood glucose and plasma antioxidant status in streptozotocin diabetic rats. Pol J Pharmacol 2003; 55: 43-49.
34. Polidori MC. Antioxidant micronutrients in the prevention of age-related diseases. J Postgrad Med 2003; 49: 229-235.
35. Polidori MC, Mecocci P, Levine M, Frei B. Short-term and long-term vitamin C supplementation in humans dose-dependently increases the resistance of plasma to ex vivo since colorimetric method used to measure tissue MDA levels is very simple, quick lipid peroxidation. Arch Biochem Biophys 2004; 423: 109-115.
36. Scott NA, Jennings PE, Brown J, Belch JJF. Gliclazide: a free radical scavenger. Eur J Pharmacol 1991; 208: 175-177.
37. Jennings PE, Scott NA, Saniabadi AR, Belch JJF. Effects of gliclazide on platelet reactivity and free radicals in type II diabetic patients: clinical assessments. Metabolism 1992; 41: 36-39.
38. Vallejo S, Angulo J, Peiró C. et al. Prevention endothelial dysfunction in streptozotocin-induced diabetic rats by gliclazide treatment. J Diabetes Complications 2000; 14: 224-233.
39. Fava D, Cassone-Faldetta M, Laurenti O, De Luca O, Ghiselli A, De Mattia G. Gliclazide improves anti-oxidant status and nitric oxide-mediated vasodilation in Type 2 diabetes. Diabet Med 2002; 19: 752-7S7.
40. Jennings PE. Vascular benefits of gliclazide beyond glycemic control. Metabolism 2000; 49: 17-20.
41. Chugh SN, Kakkar R, Kalra S, Sharma A. An evaluation of oxidative stress in diabetes mellitus during uncontrolled and controlled state and after vitamin E supplementation. J Assoc Physicians India 1999; 47: 380-383.
42. Mamputu JC, Reiner G. Signalling pathways involved in retinal endothelial cell proliferation induced by advanced glycation end products: inhibitory effects of gliclazide. Diabetes Obes Metab 2004; 6: 95-103.
43. Packer JE, Slater TF, Willson RL. Direct observation of a free radical interaction between vitamin E and vitamin C. Nature 1979; 278: 738-739.
44. Steffner RJ, Wu L, Powers AC, May JM. Ascorbic acid recycling by cultured beta cells: effects of increased glucose metabolism. Free Radic Biol Med 2004; 37: 1612-1621.
45. Palmer AM, Thomas CR, Gopaul N. et al. Dietary antioxidant supplementation reduces lipid peroxidation but impairs vascular function in small mesenteric arteries of the streptozotocin-diabetic rats. Diabetologia 1998; 41: 148-156.
46. Cederberg J, Siman CM, Eriksson UJ. Combined treatment with vitamin E and vitamin C decreases oxidative stress and improves fetal outcome in experimental diabetic pregnancy. Pediatr Res 2001; 49: 755-762.
47. van Dam PS, Bravenboer B, van Asbeck BS, Marx JJM, Gispen WH. High rat food vitamin E content improves nerve function in streptozotocin-diabetic rats. Eur J Pharmacol 1999; 376:217-222.