No effect of hippocampal lesions on perirhinal cortex-dependent feature-ambiguous visual discriminations

Hippocampus

Volumn 16, Issue 4, 2006, Pages 421-430

  Saksida, Lisa M ^a   Bussey, Timothy J ^a   Buckmaster, Cindy A ^b   Murray, Elisabeth A ^b  

^a UK   (United Kingdom)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

Discrimination learning; Inferotemporal cortex; Medial temporal lobe; Object recognition; Rhesus monkey; Ventral visual stream

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; BRAIN DAMAGE; COGNITION; CONTROLLED STUDY; HIPPOCAMPUS; MALE; MENTAL TASK; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PREDICTION; PRIORITY JOURNAL; RHESUS MONKEY; TASK PERFORMANCE; TEMPORAL LOBE; VISUAL DISCRIMINATION; VISUAL IMPAIRMENT; VISUAL MEMORY; VISUAL STIMULATION;

AGNOSIA; ANIMALS; COGNITION DISORDERS; DENERVATION; DISCRIMINATION LEARNING; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; MACACA MULATTA; MAGNETIC RESONANCE IMAGING; MALE; MEMORY; MEMORY DISORDERS; NEUROPSYCHOLOGICAL TESTS; NEUROTOXINS; PARAHIPPOCAMPAL GYRUS; PATTERN RECOGNITION, VISUAL; PERCEPTUAL DISORDERS; PHOTIC STIMULATION; VISUAL PATHWAYS;

EID: 33744466301     PISSN: 10509631     EISSN: 10981063     Source Type: Journal    
DOI: 10.1002/hipo.20170     Document Type: Article

References (52)

1. Aggleton JP, Hunt PR, Rawlins JN. 1986. The effects of hippocampal lesions upon spatial and nonspatial tests of working memory. Behav Brain Res 19:133-146.
2. Aggleton JP, Brown MW. 1999. Episodic memory, amnesia, and the hippocampal-anterior thalamic axis. Brain Behav Sci 22:425-489.
3. Alvarado MC, Bachevalier J. 2005. Comparison of the effects of damage to the perirhinal and parahippocampal cortex on transverse patterning and location memory in rhesus macaques. J Neurosci 25:1599-1609.
4. Barense MD, Bussey TJ, Lee ACH, Rogers TT, Davies RR, Saksida LM, Murray EA, Graham KS. Functional specialization in the human medial temporal lobe. J Neurosci 25:10239-10246.
5. Baxter MG, Murray EA. 2001. Opposite relationship of hippocampal and rhinal cortex damage to delayed nonmatching-to-sample deficits in monkeys. Hippocampus 11:61-71.
6. Bohbot VD, Kalina M, Stepankova K, Spackova N, Petrides M, Nadel L. 1998. Spatial memory deficits in patients with lesions to the right hippocampus and to the right parahippocampal cortex. Neuropsychologia 36:1217-1238.
7. Buckley MJ. 2005. The role of the medial temporal lobe in memory and perception: evidence from rats, nonhuman primates and humans. Q J Exp Psychol B 58:246-268.
8. Buckley MJ, Gaffan D. 1997. Impairment of visual object-discrimination learning after perirhinal cortex ablation. Behav Neurosci 111:467-475.
9. Buckley MJ, Gaffan D. 2000. The hippocampus, perirhinal cortex and memory in the monkey. In: Bolhuis JJ, editor. Brain, perception, memory: advances in cognitive neuroscience. Oxford: Oxford University Press. p 279-298.
10. Buckley MJ, Booth MC, Rolls ET, Gaffan D. 2001. Selective perceptual impairments after perirhinal cortex ablation. J Neurosci 21: 9824-9836.
11. Burgess N, Maguire EA, O'Keefe J. 2002. The human hippocampus and spatial and episodic memory. Neuron 35:625-641.
12. Bussey TJ, Aggleton JP. 2002. The "what" and "where" of event memory: independence and interactivity within the medial temporal lobe. In: Parker A, Wilding E, Bussey TJ, editors. The cognitive neuroscience of memory: encoding and retrieval. London: Psychology Press. p 217-233.
13. Bussey TJ, Saksida LM. 2002. The organization of visual object representations: a connectionist model of effects of lesions in perirhinal cortex. Eur J Neurosci 15:355-364.
14. Bussey TJ, Muir JL, Aggleton JP. 1999. Functionally dissociating aspects of event memory: the effects of combined perirhinal and postrhinal cortex lesions on object and place memory in the rat. J Neurosci 19:495-502.
15. Bussey TJ, Duck J, Muir JL, Aggleton JP. 2000. Distinct patterns of behavioural impairments resulting from fornix transection or neurotoxic lesions of the perirhinal and postrhinal cortices in the rat. Behav Brain Res 111:187-202.
16. Bussey TJ, Saksida LM, Murray EA. 2002. Perirhinal cortex resolves feature ambiguity in complex visual discriminations. Eur J Neurosci 15:365-374.
17. Bussey TJ, Saksida LM, Murray EA. 2003. Impairments in visual discrimination after perirhinal cortex lesions: testing "declarative" versus "perceptual-mnemonic" views of perirhinal cortex function. Eur J Neurosci 17:649-660.
18. Bussey TJ, Saksida LM, Murray EA. 2005. The PMFC model of perirhinal cortex function. Q J Exp Psychology B 58:269-282.
19. Eacott MJ, Gaffan D, Murray EA. 1994. Preserved recognition memory for small sets, and impaired stimulus identification for large sets, following rhinal cortex ablations in monkeys. Eur J Neurosci 6:1466-1478.
20. Eacott MJ, Machin PE, Gaffan EA. 2001. Elemental and configural visual discrimination learning following lesions to perirhinal cortex in the rat. Behav Brain Res 124:55-70.
21. Eichenbaum H, Otto T, Cohen NJ. 1994. Two functional components of the hippocampal memory system. Behav Brain Sci 17:449-518.
22. Erickson CA, Jagadeesh B, Desimone R. 2000. Learning and memory in the inferior temporal cortex of the macaque. In: Gazzaniga MS, editor. The new cognitive neurosciences. Cambridge, MA: MIT Press. p 743-752.
23. Forwood SE, Winters BD, Bussey TJ. 2005. Hippocampal lesions that abolish spatial maze performance spare object recognition memory at delays of up to 48 hours. Hippocampus 15:347-355.
24. Gaffan D. 1994a. Dissociated effects of perirhinal cortex ablation, fornix transection and amygdalectomy: evidence for multiple memory systems in the primate temporal lobe. Exp Brain Res 99:411-422.
25. Gaffan D. 1994b. Scene-specific memory for objects: a model of episodic memory impairment in monkeys with fornix transection. J Cogn Neurosci 6:305-320.
26. Gilbert PE, Kesner RP, DeCoteau WE. 1998. Memory for spatial location: role of the hippocampus in mediating spatial pattern separation. J Neurosci 18:804-810.
27. Gilbert PE, Kesner RP. 2003. Recognition memory for complex visual discriminations is influenced by stimulus interference in rodents with perirhinal cortex damage. Learn Mem 10:525-530.
28. Hampton RR, Murray EA. 2002. Stimulus representations in rhesus monkeys with perirhinal cortex lesions. Behav Neurosci 116:363-377.
29. Hampton RR, Buckmaster CA, Anuszkiewicz-Lundgren D, Murray EA. 2004a. Method for making selective lesions of the hippocampus in macaque monkeys using NMDA and a longitudinal surgical approach. Hippocampus 14:9-18.
30. Hampton RR, Hampstead BM, Murray EA. 2004b. Selective hippocampal damage in rhesus monkeys impairs spatial memory in an open-field test. Hippocampus 14:808-818.
31. King JA, Burgess N, Hartley T, Vargha-Khadem F, O'Keefe J. 2002. Human hippocampus and viewpoint dependence in spatial memory. Hippocampus 12:811-820.
32. Lee AC, Barense MD, Graham KS. 2005a. The contribution of the human medial temporal lobe to perception: bridging the gap between animal and human studies. Q J Exp Psychology 58:300-325.
33. Lee AC, Buckley MJ, Pegman SJ, Spiers H, Scahill VL, Gaffan D, Bussey TJ, Davies RR, Kapur N, Hodges JR, Graham KS. 2005b. Specialization in the medial temporal lobe for processing of objects and scenes. Hippocampus 15:782-797.
34. Lee AC, Bussey TJ, Murray EA, Saksida LM, Epstein RA, Kapur N, Hodges JR, Graham KS. 2005c. Perceptual deficits in amnesia: challenging the medial temporal lobe 'mnemonic' view. Neuropsychologia 43:1-11.
35. Levy DA, Shrager Y, Squire LR. 2005. Intact visual discrimination of complex and feature-ambiguous stimuli in the absence of perirhinal cortex. Learn Mem 12:61-66.
36. Málková L, Lex CK, Mishkin M, Saunders RC. 2001. MRI-based evaluation of locus and extent of neurotoxic lesions in monkeys. Hippocampus 11:361-370.
37. Morris RGM, Garrud P, Rawlins JNP, O'Keefe J. 1982. Place navigation impaired in rats with hippocampal lesions. Nature 297:681-683.
38. Mumby DG. 2001. Perspectives on object-recognition memory following hippocampal damage: lessons from studies in rats. Behav Brain Res 127:159-181.
39. Murray EA, Bussey TJ. 1999. Perceptual-mnemonic functions of perirhinal cortex. Trends Cogn Sci 3:142-151.
40. Murray EA, Mishkin M. 1998. Object recognition and location memory in monkeys with excitotoxic lesions of the amygdala and hippocampus. J Neurosci 18:6568-6582.
41. Murray EA, Wise SP. 2004. What, if anything, is the medial temporal lobe, and how can the amygdala be part of it if there is no such thing? Neurobiol Learn Mem 82:178-198.
42. Murray EA, Gaffan D, Mishkin M. 1993. Neural substrates of visual stimulus-stimulus association in rhesus monkeys. J Neurosci 13:4549-4561.
43. Norman G, Eacott MJ. 2004. Impaired object recognition with increasing levels of feature ambiguity in rats with perirhinal cortex lesions: Behav Brain Res 148:79-91.
44. Olton DS, Becker JT, Handelmann GE. 1979. Hippocampus, space, and memory. Behav Brain Sci 2:313-365.
45. Saksida LM, Bussey TJ. 1998. Toward a neural network model of visual object identification in primate inferotemporal cortex. Soc Neurosci Abstr 24:1906.
46. Saksida L, Bussey T, Buckmaster C, Murray E. 2003. Perirhinal cortex lesions can impair, and hippocampal lesions can facilitate, transverse patterning in rhesus monkeys. Washington, DC: Society for Neuroscience. Program number 939.12. 2003, Abstract Viewer/Itinerary Planner, online.
47. Saksida LM, Bussey TJ, Buckmaster C, Murray EA. 2006. Impairment and facilitation of transverse patterning after lesions of the perirhinal cortex and hippocampus, respectively. Cerebral Cortex, in press.
48. Squire LR, Zola-Morgan S. 1991. The medial temporal lobe memory system. Science 253:1380-1386.
49. Squire LR, Stark CE, Clark RE. 2004. The medial temporal lobe. Annu Rev Neurosci 27:279-306.
50. Stark CE, Squire LR. 2000. Intact visual perceptual discrimination in humans in the absence of perirhinal cortex. Learn Mem 7:273-278.
51. Winters BD, Forwood SE, Cowell RA, Saksida LM, Bussey TJ. 2004. Double dissociation between the effects of peri-postrhinal cortex and hippocampal lesions on tests of object recognition and spatial memory: heterogeneity of function within the temporal lobe. J Neurosci 24:5901-5908.
52. Zola-Morgan S, Squire LR, Ramus SJ. 1994. Severity of memory impairment in monkeys as a function of locus and extent of damage within the medial temporal lobe memory system. Hippocampus 4:483-495.