Perirhinal cortex resolves feature ambiguity in complex visual discriminations

European Journal of Neuroscience

Volumn 15, Issue 2, 2002, Pages 365-374

  Bussey, Timothy J ^a,b   Saksida, Lisa M ^a   Murray, Elisabeth A ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b University of Cambridge   (United Kingdom)

Author keywords

Configural learning; Discrimination learning; Inferotemporal cortex; Object recognition; Rhesus monkey; Ventral visual stream

Indexed keywords

AMBIGUITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; BRAIN FUNCTION; BRAIN INJURY; CONTROLLED STUDY; MONKEY; NONHUMAN; PERCEPTION; PRIORITY JOURNAL; SIMULATION; VISUAL DISCRIMINATION; VISUAL DISORDER;

ANIMALS; BEHAVIOR, ANIMAL; COMPUTER SIMULATION; DENERVATION; DISCRIMINATION LEARNING; MACACA MULATTA; MAGNETIC RESONANCE IMAGING; MEMORY; MODELS, NEUROLOGICAL; PATTERN RECOGNITION, VISUAL; PHOTIC STIMULATION; RNA, MESSENGER; TEMPORAL LOBE; VISUAL PATHWAYS;

EID: 0036460809     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0953-816x.2001.01851.x     Document Type: Article

References (41)

1. Bachevalier, J., Beauregard, M. & Alvarado, M.C. (1999) Long-term effects of neonatal damage to the hippocampal formation and amygdaloid complex on object discrimination and object recognition in rhesus monkeys (Macaca mulatta). Behav. Neurosci., 113, 1127-1151.
2. Bachevalier, J. & Mishkin, M. (1994) Effects of selective neonatal temporal lobe lesions on visual recognition memory in rhesus monkeys. J. Neurosci., 14, 2128-2139.
3. Baxter, M.G. & Murray, E.A. (2001) Impairments in visual discrimination learning and recognition memory produced by neurotoxic lesions of rhinal cortex in rhesus monkeys. Eur. J. Neurosci., 13, 1228-1238.
4. von Bonin, G. & Bailey, P. (1947) The Neocortex of Macaca Mulatta. University of Illinois Press, Illinois.
5. Buckley, M.J. & Gaffan, D. (1997) Impairment of visual object-discrimination learning after perirhinal cortex ablation. Behav. Neurosci., 111, 467-475.
6. Buckley, M.J. & Gaffan, D. (1998) Perirhinal cortex ablation impairs visual object identification. J. Neurosci., 18, 2268-2275.
7. Buckley, M.J. & Gaffan, D. (1998) Perirhinal cortex ablation impairs configural learning and paired-associate learning equally. Neuropsychologia, 36, 535-546.
8. Buffalo, E.A., Ramus, S.J., Clark, R.E., Teng, E., Squire, L.R. & Zola, S.M. (1999) Dissociation between the effects of damage to perirhinal cortex and area TE. Learn. Mem., 6, 572-599.
9. Buffalo, E.A., Ramus, S.J., Squire, L.R. & Zola, S.M. (2000) Perception and recognition memory in monkeys following lesions of area TE and perirhinal cortex. Learn. Mem., 7, 375-382.
10. Buffalo, E.A., Reber, P.J. & Squire, L.R. (1998) The human perirhinal cortex and recognition memory. Hippocampus, 8, 330-339.
11. Bussey, T.J., Duck, J., Muir, J.L. & Aggleton, J.P. (2000) Distinct patterns of behavioural impairments resulting from fornix transection or neurotoxic lesions of the perirhinal and postrhinal cortices in the rat. Behav. Brain Res., 111, 187-202.
12. Bussey, T.J., Muir, J.L. & Aggleton, J.P. (1999a) Functionally dissociating aspects of event memory: The effects of combined perirhinal and postrhinal cortex lesions on object and place memory in the rat. J. Neurosci., 19, 495-502.
13. Bussey, T.J. & Saksida, L.M. (2002) The organization of visual object representations: A connectionist model of effects of lesions in perirhinal cortex. Eur. J. Neurosci., 15, 355-364.
14. Bussey, T.J., Saksida, L.M. & Murray, E.A. (1999b) Overgeneralization in monkeys with perirhinal cortex lesions. Soc. Neurosci. Abstr., 25, 789.
15. Desimone, R. & Ungerleider, L.G. (1989) Neural mechanisms of visual processing in monkeys. In Boller, F. & Grafman, J. (eds), Handbook of Neuropsychology, Vol 2. Elsevier Science, New York, pp. 267-299.
16. Eacott, M.J., Gaffan, D. & Murray, E.A. (1994) Preserved recognition memory for small sets, and impaired stimulus identification for large sets, following rhinal cortex ablations in monkeys. Eur. J. Neurosci., 6, 1466-1478.
17. Eacott, M.J., Machin, P.E. & Gaffan, E.A. (2001) Elemental and configural visual discrimination learning following lesions to perirhinal cortex in the rat. Behav. Brain Res., 124, 55-70.
18. Erickson, C.A., Jagadeesh, B. & Desimone, R. (2000) Learning and memory in the inferior temporal cortex of the macaque. In Gazzaniga, M.S. (ed.), The New Cognitive Neurosciences. The MIT Press, London, pp. 743-752.
19. Friedman, D.P., Murray, E.A., O'Neill, J.B. & Mishkin, M. (1986) Cortical connections of the somatosensory fields of the lateral sulcus of macaques: Evidence for a corticolimbic pathway for touch. J. Comp. Neurol., 252, 323-347.
20. Gaffan, E., Eacott, M. & Simpson, E. (2000) Perirhinal cortex ablation in rats selectively impairs object identification in a simultaneous visual comparison task in rats. Behav. Neurosci., 114, 18-31.
21. Gaffan, D. & Murray, E.A. (1992) Monkeys (Macaca fascicularis) with rhinal cortex ablations succeed in object discrimination learning despite 24-hr intertrial intervals and fail at matching to sample despite double sample presentations. Behav. Neurosci., 106, 30-38.
22. Higuchi, S. & Miyashita, Y. (1996) Formation of mnemonic neuronal responses to visual paired associates in inferotemporal cortex is impaired by perirhinal and entorhinal lesions. Proc. Natl. Acad. Sci. USA, 93, 739-743.
23. Liu, Z., Murray, E.A. & Richmond, B.J. (2000) Learning motivational significance of visual cues for reward schedules requires rhinal cortex. Nature Neurosci., 3, 1307-1315.
24. Logothetis, N.K., Pauls, J. & Poggio, T. (1995) Shape representation in the inferior temporal cortex of monkeys. Curr. Biol., 5, 552-563.
25. Malkova, L., Bachevalier, J., Mishkin, M. & Saunders, R.C. (2001) Neurotoxic lesions of perirhinal cortex impair visual recognition memory in rhesus monkeys. Neuroreport, 12, 1913-1917.
26. Meunier, M., Bachevalier, J., Mishkin, M. & Murray, E.A. (1993) Effects on visual recognition of combined and separate ablations of the entorhinal and perirhinal cortex in rhesus monkeys. J. Neurosci., 13, 5418-5432.
27. Mumby, D.G. & Pinel, J.P.J. (1994) Rhinal cortex lesions and object recognition in rats. Behav. Neurosci., 108, 11-18.
28. Murray, E.A. (2000) Memory for objects in nonhuman primates. In Gazzaniga, M.S. (ed.), The New Cognitive Neurosciences. The MIT Press, London, pp. 753-763.
29. Murray, E.A. & Bussey, T.J. (1999) Perceptual-mnemonic functions of perirhinal cortex. Trends Cog. Sci., 3, 142-151.
30. Murray, E.A., Bussey, T.J., Saksida, L.M. & Hampton, R. (2000) The parahippocamal region and object identification. Ann. NY Acad. Sci., 911, 166-174.
31. Murray, E.A., Gaffan, D. & Mishkin, M. (1993) Neural substrates of visual stimulus-stimulus association in rhesus monkeys. J. Neurosci., 13, 4549-4561.
32. Murray, E.A., Málková, L. & Goulet, S. (1998) Crossmodal associations, intramodal associations, and object identification in macaque monkeys. In Milner, A.D. (ed.), Comparative Neuropsychology. Oxford University Press, Oxford, pp. 51-69.
33. Rescorla, R.A. & Wagner, A.R. (1972) A theory of Pavlovian conditioning: Variations in the effectiveness of reinforcement and nonreinforcement. In Black, A. & Prokasy, W.F. (eds), Classical Conditioning II. Appleton-Century-Crofts, New York, pp. 64-99.
34. Sakai, S. & Miyashita, Y. (1993) Memory and imagery in the temporal lobe. Curr. Opin. Neurobiol., 3, 166-170.
35. Saksida, L.M., Bussey, T.J. & Murray, E.A. (2000) One-pair discrimination learning in monkeys with perirhinal cortex lesions. Soc. Neurosci. Abstr., 26, 546.
36. Squire, L.R. (1992) Memory and the hippocampus: A synthesis from findings with rats, monkeys, and humans. Psychol. Rev., 99, 195-231.
37. Sutherland, R.J. & Rudy, J.W. (1989) Configural association theory: The role of the hippocampal formation in learning, memory, and amnesia. Psychobiology, 17, 129-144.
38. Suzuki, W. & Amaral, D.G. (1994) Perirhinal and parahippocampal cortices of the macaque monkey: Cortical afferents. J. Comp. Neurol., 350, 497-533.
39. Tanaka, K. (1993) Neural mechanisms of object recognition. Science, 262, 685-688.
40. Thornton, J.A., Rothblat, L.A. & Murray, E.A. (1997) Rhinal cortex removal produces amnesia for preoperatively learned discrimination problems but fails to disrupt postoperative acquisition and retention in rhesus monkeys. J. Neurosci., 17, 8536-8549.
41. Tsunoda, K., Yamane, Y., Nishizaki, M. & Tanifugi, M. (2001) Complex objects are represented in macaque inferotemporal cortex by the combination of feature columns. Nature Neurosci., 4, 832-838.