Enhanced group II mGluR-mediated inhibition of pain-related synaptic plasticity in the amygdala

Molecular Pain

Volumn 2, Issue , 2006, Pages

  Han, Jeong S ^a   Fu, Yu ^a   Bird, Gary C ^a   Neugebauer, Volker ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BICUCULLINE; CARRAGEENAN; EGLUMETAD; KAOLIN; METABOTROPIC RECEPTOR 2; ALPHA ETHYLGLUTAMIC ACID; ALPHA-ETHYLGLUTAMIC ACID; AMINO ACID RECEPTOR STIMULATING AGENT; BICYCLO COMPOUND; GLUTAMIC ACID DERIVATIVE; METABOTROPIC RECEPTOR;

AMPLITUDE MODULATION; AMYGDALOID NUCLEUS; ANALGESIC ACTIVITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRALGIA; ARTHRITIS; ARTICLE; BRAIN NERVE CELL; BRAIN SLICE; CONTROLLED STUDY; DRUG POTENCY; ELECTROSTIMULATION; EXCITATORY POSTSYNAPTIC POTENTIAL; IC 50; MALE; MONOSYNAPTIC POTENTIAL; NERVE CELL EXCITABILITY; NERVE CELL PLASTICITY; NERVE POTENTIAL; NEUROMODULATION; NONHUMAN; PARABRACHIAL NUCLEUS; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; VOLTAGE CLAMP; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; PAIN; PATHOPHYSIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; SYNAPTIC POTENTIAL; SYNAPTIC TRANSMISSION;

AMYGDALA; ANIMALS; ARTHRITIS, EXPERIMENTAL; BICYCLO COMPOUNDS; EXCITATORY AMINO ACID AGONISTS; GLUTAMATES; MALE; NEURONAL PLASTICITY; PAIN; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, METABOTROPIC GLUTAMATE; SYNAPTIC POTENTIALS; SYNAPTIC TRANSMISSION;

EID: 33744466277     PISSN: 17448069     EISSN: None     Source Type: Journal    
DOI: 10.1186/1744-8069-2-18     Document Type: Article

References (55)

1. Phelps EA, Ledoux JE: Contributions of the Amygdala to Emotion Processing: From Animal Models to Human Behavior. Neuron 2005, 48:175-187.
2. Davidson RJ: Anxiety and affective style: role of prefrontal cortex and amygdala. Biol Psychiatry 2002, 51:68-80.
3. Maren S: Synaptic Mechanisms of Associative Memory in the Amygdala. Neuron 2005, 47:783-786.
4. Gallagher RM, Verma S: Mood and anxiety disorders in chronic pain. Prog in Pain Res Management 2004, 27:139-178.
5. Neugebauer V, Li W, Bird GC, Han JS: The amygdala and persistent pain. The Neuroscientist 2004, 10:221-234.
6. Hebert MA, Ardid D, Henrie JA, Tamashiro K, Blanchard DC, Blanchard RJ: Amygdala lesions produce analgesia in a novel, ethologically relevant acute pain test. Physiol Behav 1999, 67:99-105.
7. Nandigama P, Borszcz GS: Affective analgesia following the administration of morphine into the amygdala of rats. Brain Res 2003, 959:343-354.
8. Han JS, Li W, Neugebauer V: Critical role of calcitonin gene-related peptide I receptors in the amygdala in synaptic plasticity and pain behavior. J Neurosci 2005, 25:10717-10728.
9. Bornhovd K, Quante M, Glauche V, Bromm B, Weiller C, Buchel C: Painful stimuli evoke different stimulus-response functions in the amygdala, prefrontal, insula and somatosensory cortex: a single-trial fMRI study. Brain 2002, 125:1326-1336.
10. Bonaz B, Baciu M, Papillon E, Bost R, Gueddah N, Le Bas JF, Fournet J, Segebarth C: Central processing of rectal pain in patients with irritable bowel syndrome: an fMRI study. Am J Gastroenterol 2002, 97:654-661.
11. Schneider F, Habel U, Holthusen H, Kessler C, Posse S, Muller-Gartner HW, Arndt JO: Subjective ratings of pain correlate with subcortical-limbic blood flow: an fMRI study. Neuropsychobiology 2001, 43:175-185.
12. Bingel U, Quante M, Knab R, Bromm B, Weiller C, Buchel C: Subcortical structures involved in pain processing: evidence from single-trial fMRI. Pain 2002, 99:313-321.
13. Gauriau C, Bernard J-F: Pain pathways and parabrachial circuits in the rat. Exp Physiol 2002, 87:251-258.
14. Jasmin L, Burkey AR, Card JP, Basbaum AI: Transneuronal labeling of a nociceptive pathway, the spino-(trigemino-)parabrachio-amygdaloid, in the rat. J Neurosci 1997, 17:3751-3765.
15. Braz JM, Nassar MA, Wood JN, Basbaum AI: Parallel "pain" pathways arise from subpopulations of primary afferent nociceptor. Neuron 2005, 47:787-793.
16. LeDoux JE: Emotion circuits in the brain. Ann Rev Neuroscience 2000, 23:155-184.
17. Heinricher MM, McGaraughty S: Pain-modulating neurons and behavioral state. In Handbook of Behavioral State Control Edited by: Lydic R, Baghdoyan HA. New york: CRC Press; 1999:487-503.
18. Neugebauer V, Li W: Differential sensitization of amygdala neurons to afferent inputs in a model of arthritic pain. J Neurophysiol 2003, 89:716-727.
19. Li W, Neugebauer V: Differential roles of mGluR1 and mGluR5 in brief and prolonged nociceptive processing in central amygdala neurons. J Neurophysiol 2004, 91:13-24.
20. Li W, Neugebauer V: Block of NMDA and non-NMDA receptor activation results in reduced background and evoked activity of central amygdala neurons in a model of arthritic pain. Pain 2004, 110:112-122.
21. Neugebauer V, Li W, Bird GC, Bhave G, Gereau RW: Synaptic plasticity in the amygdala in a model of arthritic pain: differential roles of metabotropic glutamate receptors 1 and 5. J Neurosci 2003, 23:52-63.
22. Bird GC, Lash LL, Han JS, Zou X, Willis WD, Neugebauer V: PKA-dependent enhanced NMDA receptor function in pain-related synaptic plasticity in amygdala neurons. J Physiol 2005, 564.3:907-921.
23. Han JS, Bird GC, Neugebauer V: Enhanced group III mGluR-mediated inhibition of pain-related synaptic plasticity in the amygdala. Neuropharmacology 2004, 46:918-926.
24. Swanson CJ, Bures M, Johnson MP, Linden AM, Monn JA, Schoepp DD: Metabotropic glutamate receptors as novel targets for anxiety and stress disorders. Nat Rev Drug Discov 2005, 4:131-144.
25. Schoepp DD, Jane DE, Monn JA: Pharmacological agents acting at subtypes of metabotropic glutamate receptors. Neuropharmacology 1999, 38:1431-1476.
26. Neugebauer V: Metabotropic glutamate receptors: novel targets for pain relief. Exp Rev Neurother 2001, 1:207-224.
27. Neugebauer V, Carlton SM: Peripheral metabotropic glutamate receptors as drug targets for pain relief. Expert Opin on Ther Targets 2002, 6:349-361.
28. Lesage ASJ: Role of group I metabotropic glutamate receptors mGlu1 and mGlu5 in nociceptive signalling. Curr Neuropharm 2004, 2:363-393.
29. Fundytus ME: Glutamate receptors and nociception. Implications for the drug treatment of pain. CNS Drugs 2001, 15:29-58.
30. Varney MA, Gereau RW: Metabotropic glutamate receptor involvement in models of acute and persistent pain: prospects for the development of novel analgesics. Current Drug Targets 2002, 1:215-225.
31. Marek GJ: Metabotropic glutamate 2/3 receptors as drug targets. Curr Opin Pharmacol 2004, 4:18-22.
32. Jane DE, Thomas NK, Tse HW, Watkins JC: Potent antagonists at the L-AP4 and (1S,3S)-ACPD-sensitive presynaptic metabotropic glutamate receptors in the neonatal rat spinal cord. Neuropharmacology 1996, 35:1029-1035.
33. McKernan MG, Shinnick-Gallagher P: Fear conditioning induces a lasting potentiation of synaptic currents in vitro. Nature 1997, 390:607-611.
34. Neugebauer V, Keele NB, Shinnick-Gallagher P: Epileptogenesis in vivo enhances the sensitivity of inhibitory presynaptic metabotropic glutamate receptors in basolateral amygdala neurons in vitro. J Neurosci 1997, 17:983-995.
35. Neugebauer V, Zinebi F, Russell R, Gallagher JP, Shinnick-Gallagher P: Cocaine and kindling alter the sensitivity of group II and III metabotropic glutamate receptors in the central amygdala. J Neurophysiol 2000, 84:759-770.
36. Cartmell J, Schoepp DD: Regulation of neurotransmitter release by metabotropic glutamate receptors. J Neurochem 2000, 75:889-907.
37. Bushell TJ, Jane DE, Tse HW, Watkins JC, Garthwaite J, Collingridge GL: Pharmacological antagonism of the actions of group II and III mGluR agonists in the lateral perforant path of rat hippocampal slices. Br J Pharmacol 1996, 117:1457-1462.
38. Salt TE, Eaton SA, Turner JP: Characterization of the metabotropic glutamate receptors (mGluRs) which modulate GABA-mediated inhibition in the ventrobasal thalamus. Neurochem Int 1996, 29:317-322.
39. Ohishi H, Shigemoto R, Nakanishi S, Mizuno N: Distribution of the mRNA for a metabotropic glutamate receptor (mGluR3) in the rat brain: an in situ hybridization study. J Comp Neurol 1993, 335:252-266.
40. Ohishi H, Shigemoto R, Nakanishi S, Mizuno N: Distribution of the messenger RNA for a metabotropic glutamate receptor, mGluR2, in the central nervous system of the rat. Neuroscience 1993, 53:1009-1018.
41. Wang L, Kitai ST, Xiang Z: Modulation of excitatory synaptic transmission by endogenous glutamate acting on presynaptic group II mGluRs in rat substantia nigra compacta. J Neurosci Res 2005, 82:778-787.
42. Price CJ, Karayannis T, Pal BZ, Capogna M: Group II and III mGluRs-mediated presynaptic inhibition of EPSCs recorded from hippocampal interneurons of CAI stratum lacunosum moleculare. Neuropharmacology 2005, 49(Suppl 1):45-56.
43. Manzoni OJ, Castillo PE, Nicoll RA: Pharmacology of metabotropic glutamate receptors at the mossy fiber synapses of the guinea pig hippocampus. Neuropharmacology 1995, 34:965-971.
44. Lovinger DM, McCool BA: Metabotropic glutamate receptor-mediated presynaptic depression at corticostriatal synapses involves mGLuR2 or 3. J Neurophysiol 1995, 73:1076-1083.
45. Yang D, Gereau RW: Peripheral Group II Metabotropic Glutamate Receptors (mGluR2/3) Regulate Prostaglandin E2-Mediated Sensitization of Capsaicin Responses and Thermal Nociception. J Neurosci 2002, 22:6388-6393.
46. Yang D, Gereau RW: Peripheral group II metabotropic glutamate receptors mediate endogenous anti-allodynia in inflammation. Pain 2003, 106:411-417.
47. Jang JH, Kim DW, Sang Nam T, Se Paik K, Leem JW: Peripheral glutamate receptors contribute to mechanical hyperalgesia in a neuropathic pain model of the rat. Neuroscience 2004, 128:169-176.
48. Dolan S, Nolan AM: Behavioral evidence supporting a differential role for spinal group I and II metabotropic glutamate receptors in inflammatory hyperalgesia in sheep. Neuropharmacology 2002, 43:319-326.
49. Soliman AC, Yu JSC, Coderre TJ: mGlu and NMDA receptor contributions to capsaicin-induced thermal and mechanical hypersensitivity. Neuropharmacology 2005, 48:325-332.
50. Neugebauer V, Chen P-S, Willis WD: Groups II and III metabotropic glutamate receptors differentially modulate brief and prolonged nociception in primate STT cells. J Neurophysiol 2000, 84:2998-3009.
51. Stanfa LC, Dickenson AH: Inflammation alters the effects of mGlu receptor agonists on spinal nociceptive neurones. Eur J Pharmacol 1998, 347:165-172.
52. Jones CK, Eberle EL, Peters SC, Monn JA, Shannon HE: Analgesic effects of the selective group II (mGlu2/3) metabotropic glutamate receptor agonists LY379268 and LY389795 in persistent and inflammatory pain models after acute and repeated dosing. Neuropharmacology 2005, 49:206-218.
53. Simmons RM, Webster AA, Kalra AB, Iyengar S: Group II mGluR receptor agonists are effective in persistent and neuropathic pain models in rats. Pharmacol Biochem and Behav 2002, 73:419-427.
54. Maione S, Oliva P, Marabese I, Palazzo E, Rossi F, Berrino L, Rossi F, Filippelli A: Periaqueductal gray matter metabotropic glutamate receptors modulate formalin-induced nociception. Pain 2000, 85:183-189.
55. Salt TE: Glutamate receptor functions in sensory relay in the thalamus. Philos Trans R Soc of Lond B, Biol Sci 2002, 357:1759-1766.