JNK (c-Jun NH2 terminal kinase) and p38 during ischemia reperfusion injury in the small intestine

Transplantation

Volumn 81, Issue 9, 2006, Pages 1325-1330

  Murayama, Takaya ^a   Tanabe, Minoru ^a   Matsuda, Satoshi ^a   Shimazu, Motohide ^a   Kamei, Shusaku ^a   Wakabayashi, Go ^a   Kawachi, Shigeyuki ^a   Matsumoto, Kenji ^a   Yamazaki, Kazuto ^b   Matsumoto, Koshi ^c   Koyasu, Shigeo ^a   Kitajima, Masaki ^a  

^a KEIO UNIVERSITY   (Japan)

^b SAISEIKAI CENTRAL HOSPITAL   (Japan)

^c NIPPON MEDICAL SCHOOL MUSASHI KOSUGI HOSPITAL   (Japan)

Author keywords

Ischemia reperfusion; JNK; p38; Small intestine

Indexed keywords

DNA NUCLEOTIDYLEXOTRANSFERASE; MITOGEN ACTIVATED PROTEIN KINASE P38; RADICICOL; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTERY CLAMP; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME LOCALIZATION; EPITHELIUM CELL; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INTESTINE BLOOD FLOW; INTESTINE ISCHEMIA; MALE; NICK END LABELING; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; SMALL INTESTINE; SUPERIOR MESENTERIC ARTERY;

ANIMALS; APOPTOSIS; ENZYME ACTIVATION; IN SITU NICK-END LABELING; INTESTINAL MUCOSA; INTESTINE, SMALL; MALE; MICROVILLI; MITOGEN-ACTIVATED PROTEIN KINASE 8; MODELS, ANIMAL; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RATS; RATS, WISTAR; REPERFUSION INJURY;

EID: 33744458203     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.tp.0000209167.48030.6b     Document Type: Article

References (29)

1. Abu-Elmagd K, Reyes J, Bond G, et al. Clinical intestinal transplantation: a decade of experience at a single center. Ann Surg 2001; 234: 404-417.
2. 1-3. Transplantation 1999; 67: 1061-1064.
3. Kong SE, Blennerhassett LR, Heel KA, et al. Ischemia-reperfusion injury to the intestine. Aust NZ J Surg 1998; 68: 554-561.
4. Land W, Messmer K. The impact of ischemia/reperfusion injury on specific and non-specific, early and late chronic events after organ transplantation. Transplant Rev 1996; 10: 108-127.
5. Yamamoto S, Tanabe M, Wakabayashi G, et al. The role of tumor necrosis factor-α and interleukin-1β in ischemia-reperfusion injury of the rat small intestine. J Surg Res 2001; 99: 134-141.
6. Fink MP. Another negative clinical trial of a new agent tor the treatment of sepsis: Rethinking the process of developing adjuvant treatments for serious infections. Crit Care Med 1995; 23: 989-991.
7. Wheeler AP, Bernard GR. Treating patients with severe sepsis. N Engl J Med 1999; 340: 207-214.
8. Lee JC, Laydon JT, McDonnell PC, et al. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 1994; 372: 739-746.
9. Herlaar E, Brown Z. p38 MAPK signaling cascades in inflammatory disease. Mol Med Today 1999; 5: 439-447.
10. Ma XL, Kumar S, Gao F, et al. Inhibition of p38 mitogen-activated protein kinase decreases cardiomyocyte apoptosis and improves cardiac function after myocardial ischemia and reperfusion. Circulation 1999; 99: 1685-1691.
11. Hommes D, Blink BVD, Plasse T, et al. Inhibition of stress-activated MAP kinases induced clinical improvement in moderate to severe Crohn's disease. Gastroenterology 2002; 122: 7-14.
12. Force T, Bonventre JV. Growth factors and mitogen-activated protein kinases. Hypertension 1998; 31: 152-161.
13. Sugden PH, Clerk A. "Stress-responsive" mitogen-activated protein kinases (c-Jun N-terminal kinases and p38 mitogen-activated protein kinases) in the myocardium. Circ Res 1998; 83: 345-352.
14. Clerk A, Fuller SJ, Michael A, Sugden PH. Stimulation of "stress-regulated" mitogen-activated protein kinases (stress-activated protein kinases/c-Jun N-terminal kinases and p38-mitogen-activated protein kinases) in perfused rat hearts by oxidative and other stresses. J Biol Chem 1998; 273: 7228-7234.
15. Hreniuk D, Garay M, Gaarde W, et al. Inhibition of c-Jun N-terminal kinase 1, but not c-Jun N-terminal kinase 2, suppresses apoptosis induced by ischemia/reoxygenation in rat cardiac myocytes. Mol Pharmacol 2001; 59: 867-874.
16. Takehana K, Sato S, Kobayasi T, Maeda T. A radicicol-related macrocyclic nonaketide compound, antibiotic LL-Z1640-2, inhibits the JNK/ p38 pathways in signal-specific manner. Biochem Biophys Res Commun 1999; 257: 19-23.
17. Megison SM, Horton JW, Chao H, Walker PB. A new model for intetinal ischemia in the rat. J Surg Res 1990; 49: 168-173.
18. Park PO, Haglund U, Bulkley GB, Fält K. The sequence of development of intestinal tissue injury after strangulation ischemia and reperfusion. Surgery 1990; 107: 574-580.
19. Ikeda H, Suzuki Y, Suzuki M, et al. Apoptosis is a major mode of cell death caused by ischaemia and ischaemia/reperfusion injury to the rat intestinal epithelium. Gut 1998; 42: 530-537.
20. Zhuang S, Demirs JT, Kochevar IE. p38 mitogen activated protein kinase mediates Bid cleavage, mitochondrial dysfunction, and caspase-3 activation during apoptosis induced by singlet oxygen but not by hydrogen peroxide. J Biol Chem 2000; 275: 25939-25948.
21. Cheng A, Chan SL, Milhavet O, et al. p38 MAP kinase mediates nitric oxide-induced apoptosis of neural progenitor cells. J Biol Chem 2001; 276: 43320-43327.
22. Krilleke D, Ucur E, Pulte D, et al. Inhibition of JNK signaling diminishes early but not late cellular stress-induced apoptosis. Int J Cancer 2003; 107: 520-527.
23. Read MA, Whitley MZ, Gupta S, et al. Tumor necrosis factor α-induced E-selectin expression is activated by the nuclear factor κ and c-Jun N-terminal kinase/p38 mitogen-activated protein kinase pathways. J Biol Chem 1997; 272: 2753-2761.
24. Mizukami Y, Yoshioka K, Morimoto S, Yoshida K. A novel mechanism of JNK1 activation. J Biol Chem 1997; 272: 16657-16662.
25. Raingeaud J, Gupta S, Rogers JS, et al. Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J Biol Chem 1995; 270: 7420-7426.
26. Brenner B, Koppenhoefer U, Weinstock C, et al. Fas- or ceramide-induced apoptosis is mediated by a Rac1-regulated activation of Jun N-terminal kinase/p38 kinases and GADD153. J Bio Chem 1997; 272: 22173-22181.
27. Ding Q, Wang Q, Evers BM. Alterations of MAPK activities associated with intestinal cell differentiation. Biochem Biophys Res Commun 2001; 284: 282-288.
28. Potten CS, Booth C, Pritchard DM. The intestinal epithelial stem cell: the mucosal governor. Int J Exp Pathol 1997; 78: 219-243.
29. Zhang W, Liu HT. MAPK signal pathways in the regulation of cell proliferation in mammalian cells. Cell Res 2002; 12: 9-18.