Detection of mRNA levels for the estrogen alpha, estrogen beta and androgen nuclear receptor genes in archival breast cancer tissue

Cancer Letters

Volumn 237, Issue 2, 2006, Pages 248-255

  Smith, Robert A ^a   Lea, Rod A ^a   Weinstein, Stephen R ^b   Griffiths, Lyn R ^a  

^a Wesley Research Institute   (Australia)

^b GOLD COAST UNIVERSITY HOSPITAL   (Australia)

Author keywords

Androgen receptor; Breast cancer; Estrogen receptor; Expression; Nuclear receptor

Indexed keywords

ANDROGEN RECEPTOR; CELL NUCLEUS RECEPTOR; COMPLEMENTARY DNA; ESTROGEN; MESSENGER RNA;

ANALYSIS OF VARIANCE; ARTICLE; BREAST CANCER; CANCER GRADING; CANCER TISSUE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; POST HOC ANALYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RIBOSOME; RNA EXTRACTION;

BREAST NEOPLASMS; DNA PRIMERS; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; POLYMERASE CHAIN REACTION; RECEPTORS, ANDROGEN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 33646947828     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2005.06.013     Document Type: Article

References (21)

1. Fryer C.J., Kinyamu H.K., Rogatsky I., Garabedian M.J., and Archer T.K. Selective activation of the glucocorticoid receptor by steroid antagonists in human breast cancer and osteosarcoma cells. The Journal of Biological Chemistry 275 (2000) 17771-17777
2. Keightley M.-C. Steroid receptor isoforms: exception or rule?. Molecular and Cellular Endocrinology 137 (1998) 1-5
3. McEwan I.J. Gene regulation through chromatin remodelling by members of the nuclear receptor superfamily. Biochemical Society Transactions 28 (2000) 369-373
4. Dickson R.B., and Lippman M.E. Control of human breast cancer by estrogen, growth factors, and oncogenes. Cancer Treatment and Research 40 (1988) 119-165
5. Verrijdt G., Haelens A., and Claessens F. Selective DNA recognition by the androgen receptor as a mechanism for hormone-specific regulation of gene expression. Molecular Genetics and Metabolism 78 (2003) 175-185
6. Miller W.R. Biological rationale for endocrine therapy in breast cancer. Best Practice & Research Clinical Endocrinology & Metabolism 18 (2004) 1-32
7. Nilsson S., Makela S., Trueter F., Tujague M., Thomsen J., Andersson G., et al. Mechanisms of estrogen action. Physiological Reviews 81 (2001) 1535-1565
8. Grandien K.A.J., Berkenstam A., and Gustafsson J.-A. The estrogen receptor gene: promoter organisation and expression. The International Journal of Biochemistry & Cell Biology 29 (1997) 1343-1369
9. Yoo K.-Y., Tajima K., Park S.-K., Kang D., Kim S.-U., Hirose K., et al. Postmenopausal obesity as a breast cancer risk factor according to estrogen and progesterone receptor status (Japan). Cancer Letters 167 (2001) 57-63
10. Gobinet J., Poujol N., and Sultan C. Molecular action of androgens. Molecular and Cellular Endocrinology 198 (2002) 15-24
11. Ferro P., Catalano M.G., Dell'Eva R., Fortunati N., and Pfeffer U. The androgen receptor CAG repeat: a modifier of carcinogenesis?. Molecular and Cellular Endocrinology 193 (2002) 109-120
12. Kuenen-Boumeester V., Van der Kwast T.H., Claassen C.C., Look M.P., Liem G.S., Klijn J.G.M., and Henzen-Logmans S.C. The clinical significance of androgen receptors in breast cancer and their relation to histological and cell biological parameters. The European Journal of Cancer 32A (1996) 1560-1565
13. Andò S., De Amicis F., Rago V., Carpino A., Maggiolini M., Panno M.L., and Lanzino M. Breast cancer: from estrogen to androgen receptor. Molecular and Cellular Endocrinology 193 (2002) 121-128
14. Bentel J.M., Birrell S.N., Pickering M.A., Holds D.J., Horsfall D.J., and Tilley W.D. Androgen receptor agonist activity of the synthetic progestin, medroxyprogesterone acetate, in human breast cancer cells. Molecular and Cellular Endocrinology 154 (1999) 11-20
15. Birrell S.N., Bentel J.M., Hickey T.E., Ricciardelli C., Weger M.A., Horsfall D.J., and Tilley W.D. Androgens induce divergent proliferative responses in human breast cancer cell lines. The Journal of Steroid Biochemistry and Molecular Biology 52 (1995) 459-467
16. Selvey S., Thompson E.W., Matthaei K., Lea R.A., Irving M.G., and Griffiths L.R. β-actin-an unsuitable internal control for RT-PCR. Molecular and Cellular Probes 15 (2001) 307-311
17. Aerts J.L., Gonzales M.I., and Topalian S.L. Selection of appropriate control genes to assess expression of tumor antigens using real-time RT-PCR. Biotechniques 36 (2004) 84-86 see also 88, 90-1
18. D.L. Morse, D. Carroll, L. Weberg, M.C. Borgstrom, J. Ranger-Moore, R.J. Gillies, Determining suitable internal standards for mRNA quantification of increasing cancer progression in human breast cells by real-time reverse transcriptase polymerase chain reaction, Analytical Biochemistry, in press.
19. Smith R.A., Lea R.A., Curran J.E., Weinstein S.R., and Griffiths L.R. Expression of glucocorticoid and progesterone nuclear receptor genes in archival breast cancer tissue. Breast Cancer Research 5 (2003) R9-R12
20. O'Neill P.A., Davies M.P., Shaaban A.M., Innes H., Torevell A., Sibson D.R., and Foster C.S. Wild-type oestrogen receptor beta (ERbeta1) mRNA and protein expression in Tamoxifen-treated post-menopausal breast cancers. British Journal of Cancer 9 (2004) 1694-1702
21. Fasco M.J., Keyomarsi K., Arcaro K.F., and Gierthy J.F. Expression of an estrogen receptor alpha variant protein in cell lines and tumors. Molecular and Cellular Endocrinology 162 (2000) 167-180