Synthesis of hexa- to tridecasaccharides related to Shigella dysenteriae type 1 for incorporation in experimental vaccines

Carbohydrate Research

Volumn 341, Issue 10, 2006, Pages 1408-1427

  Pozsgay, Vince ^a   Ekborg, Göran ^a   Sampathkumar, Srinivasa Gopalan ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

Antibacterial; Benzophenone ketal; Conjugation; Oligosaccharide; Protecting groups; Synthesis; Vaccine

Indexed keywords

BACTERIA; GLYCOLS; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE; ORGANIC SOLVENTS; POLYSACCHARIDES; SYNTHESIS (CHEMICAL);

ANTIBACTERIAL; BENZOPHENONE KETAL; CONJUGATION; OLIGOSACCHARIDE; PROTECTING GROUPS; VACCINE;

VACCINES;

2 O ACETYL 3,4,6 TRI O BENZYL ALPHA DEXTRO GALACTOPYRANOSYL (1-3) 2 ACETAMIDO 4,6 DI O ACETYL 2 DEOXY ALPHA DEXTRO GLUCOPYRANOSYL(1-3) 2 O BENZOYL 4 O BENZYL ALPHA LEVO RHAMNOPYRANOSYL TRICHLOROACETAMIDATE; 5 (METHOXYCARBONYL)PENTYL 2 AZIDO 3 O CHLOROACETYL 2 DEOXY 4,6 O DIPHENYLMETHYLIDENE ALPHA DEXTRO GLUCOPYRANOSYL (1-3) 2 O BENZOYL 4 O STEAROYL ALPHA LEVO RHAMNOPYRANOSIDE; 5 (METHOXYCARBONYL)PENTYL 2 AZIDO 4,6 DI O ACETYL 2 DEOXY 3 O CHLOROACETYL ALPHA DEXTRO GLUCOPYRANOSYL (1-3) 2 O BENZOYL 4 O STEAROYL ALPHA LEVO RHAMNOPYRANOSIDE; CARBOHYDRATE DERIVATIVE; PHENYL 2 AZIDO 2 DEOXY 4,6 O DIPHENYLMETHYLIDENE 1 THIO BETA DEXTRO GLUCOPYRANOSIDE; PHENYL 2 AZIDO 3 O CHLOROACETYL 2 DEOXY 4,6 O DIPHENYLMETHYLIDENE 1 THIO BETA DEXTRO GLUCOPYRANOSIDE; UNCLASSIFIED DRUG; VACCINE;

ARTICLE; BACTERIAL STRAIN; CARBOHYDRATE SYNTHESIS; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG COATING; GLYCOSIDATION; GRAM NEGATIVE BACTERIUM; IMMUNOGENICITY; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SHIGELLA DYSENTERIAE; STRUCTURAL HOMOLOGY; STRUCTURE ANALYSIS;

CARBOHYDRATE SEQUENCE; MOLECULAR SEQUENCE DATA; O ANTIGENS; OLIGOSACCHARIDES; POLYSACCHARIDES; SHIGELLA DYSENTERIAE; SHIGELLA VACCINES;

NEGIBACTERIA; SHIGELLA DYSENTERIAE; TETRA;

EID: 33646928457     PISSN: 00086215     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carres.2006.04.006     Document Type: Article

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