Precursor limitations in methyl jasmonate-induced Catharanthus roseus cell cultures

Plant Cell Reports

Volumn 25, Issue 6, 2006, Pages 607-612

  Lee Parsons, Carolyn W T ^a   Royce, Amber J ^a  

^a NORTHEASTERN UNIVERSITY   (United States)

Author keywords

Ajmalicine; Catharanthus roseus; Loganin; Methyl jasmonate; Precursor feeding; Tryptamine

Indexed keywords

BIOSYNTHESIS; GENES;

AJMALICINE; CATHARANTHUS ROSEUS; LOGANIN; METHYL JASMONATE; PRECURSOR FEEDING; TRYPTAMINE;

PLANT CELL CULTURE;

ACETIC ACID DERIVATIVE; AJMALICINE; CYCLOPENTANE DERIVATIVE; GERANIOL; IRIDOID; JASMONIC ACID METHYL ESTER; LOGANIN; RAUWOLFIA ALKALOID; TERPENE; TRYPTAMINE; TRYPTAMINE DERIVATIVE;

ARTICLE; CATHARANTHUS; CELL CULTURE; DRUG EFFECT; METABOLISM;

ACETIC ACIDS; CATHARANTHUS; CELLS, CULTURED; CYCLOPENTANES; IRIDOIDS; SECOLOGANIN TRYPTAMINE ALKALOIDS; TERPENES; TRYPTAMINES;

BIOSYNTHESIS; PLANTS; TISSUE CULTURE;

CATHARANTHUS ROSEUS;

EID: 33646877044     PISSN: 07217714     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00299-005-0109-y     Document Type: Article

References (25)

1. Aerts RJ, Gisi D, De Carolis E, De Luca V, Bauman TW (1994) Methyl jasmonate vapor increases the developmentally controlled synthesis of alkaloids in Catharanthus and Cinchona seedlings. Plant J 5:635-643
2. Collu G, Unver N, Peltenburg-Looman AMG, van der Heijden R, Verpoorte R, Memelink J (2001) Geraniol 10-hydroxylase, a cytochrome P450 enzyme involved in terpenoid indole alkaloid biosynthesis. FEBS Lett 508:215-220
3. Collu G, Alonso Garcia A, van der Heijden R, Verpoorte R (2002) Activity of the cytochrome P450 enzyme geraniol 10-hydroxylase and alkaloid production in plant cell cultures. Plant Sci 162(1):165-172
4. Contin A, van der Heijden R, ten Hoopen HJG, Verpoorte R (1998) The inoculum size triggers tryptamine or secologanin biosynthesis in a Catharanthus roseus cell culture. Plant Sci 139:205-211
5. El-Sayed M, Verpoorte R (2002) Effect of phytohormones on growth and alkaloid accumulation by a Catharanthus roseus cell suspension cultures fed with alkaloid precursors tryptamine and loganin. Plant Cell Tissue Org Cult 68(3):265-270
6. Gamborg OL, Miller RA, Ojima K (1968) Nutrient requirements of suspension cultures of soybean root cells. Exp Cell Res 50:155-158
7. Gantet P, Imbault N, Thiersault M, Doireau P (1998) Necessity of a functional octadecanoid pathway for indole alkaloid synthesis by Catharanthus roseus cell suspensions cultured in an auxin-starved medium. Plant Cell Physiol 39:220-225
8. Gundlach H, Muller MJ, Kutchan TM, Zenk MH (1992) Jasmonic acid is a signal transducer in elicitor-induced plant cell cultures. Proc Natl Acad Sci USA 89:2389-2393
9. Hong S-B, Hughes EH, Shanks JV, San K-Y, Gibson SI (2003) Role of the non-mevalonate pathway in indole alkaloid production by Catharanthus roseus hairy roots. Biotechnol Prog 19(3):1105-1108
10. Lee-Parsons CWT, Ertürk S, Tengtrakool J (2004) Enhancement of ajmalicine production in Catharanthus roseus cell cultures with methyl jasmonate is dependent on timing and dosage of elicitation. Biotechnol Lett 26(20):1595-1599
11. Memelink J, Verpoorte R, Kijne W (2001) ORCAnization of jasmonate-responsive gene expression in alkaloid metabolism. Trends Plant Sci 6:212-219
12. Menke FLH, Parchmann S, Mueller MJ, Kijne JW, Memelink J (1999a) Involvement of the octadecanoid pathway and protein phosphorylation in fungal elicitor-induced expression of terpenoid indole alkaloid biosynthetic genes in Catharanthus roseus. Plant Physiol 119:1289-129
13. Menke FLH, Champion A, Kijne JW, Memelink J (1999b) A novel jasmonate- and elicitor-responsive element in the periwinkle secondary metabolite biosynthetic gene Str interacts with a jasmonate- and elicitor-inducible AP2-domain transcription factor, ORCA2. EMBO J 18:4455-4463
14. Moreno PRH, van der Heijden R, Verpoorte R (1993) Effect of terpenoid precursor feeding and elicitation on formation of indole alkaloids in cell suspension cultures of Catharanthus roseus. Plant Cell Rep 12(12):702-705
15. Morgan JA, Shanks JV (2000) Determination of metabolic rate-limitations by precursor feeding in Catharanthus roseus hairy root cultures. J Biotechnol 79:137-145
16. Naudascher F, Doireau P, Guillot A, Viel C, Thiersault M (1989a) Time-course studies on the use of secologanin by Catharanthus roseus cells cultured in vitro. J Plant Physiol 134:608-612
17. Naudascher F, Doireau P, Guillot A, Thiersault M (1989b) Time-course studies on the use of loganin by Catharanthus roseus cells cultured in vitro. J Plant Physiol 135:366-368
18. Rijhwani SK, Shanks JV (1998) Effect of elicitor dosage and exposure time on biosynthesis of indole alkaloids by Catharanthus roseus hairy root cultures. Biotechnol Progr 14:442-449
19. Schiel O, Witte L, Berlin J (1987) Geraniol-10-hydroxylase activity and its relation to monoterpene indole alkaloid accumulation in cell suspension cultures of Catharanthus roseus. Z. Naturforsch C 42(9-10):1075-1081
20. Van der Fits L, Memelink J (2000) ORCA3, a jasmonate-responsive transcriptional regulator of plant primary and secondary metabolism. Science 289:295-297
21. Van der Fits L, Memelink J (2001) The jasmonate-inducible AP2/ERF-domain transcription factor ORCA3 activates gene expression via interaction with a jasmonate-responsive promoter element. Plant J 25:43-53
22. Whitmer S, Canel C, Hallard D, Goncalves C, Verpoorte R (1998) Influence of precursor availability on alkaloid accumulation by transgenic cell line of Catharanthus roseus. Plant Physiol 116(2):853-857
23. Whitmer S, van der Heijden R, Verpoorte R (2002a) Effect of precursor feeding on alkaloid accumulation by a strictosidine synthase over-expressing transgenic cell line S1 of Catharanthus roseus. Plant Cell Tiss Org Cult 69(1):85-93
24. Whitmer S, van der Heijden R, Verpoorte R (2002b) Effect of precursor feeding on alkaloid accumulation by a tryptophan decarboxylase over-expressing transgenic cell line T22 of Catharanthus roseus. J Biotechnol 96(2):193-203
25. Wong PL, Royce AJ, Lee-Parsons CWT (2004) Improved ajmalicine production and recovery from Catharanthus roseus suspensions with increased product removal rates. Biochem Eng J 21:253-258