Effect of elicitor dosage and exposure time on biosynthesis of indole alkaloids by Catharanthus roseus hairy root cultures

Biotechnology Progress

Volumn 14, Issue 3, 1998, Pages 442-449

  Rijhwani, Sushil K ^a,b   Shanks, Jacqueline V ^a  

^a Rice University   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CELL CULTURE MONITORING; DETERMINATION OF CONTENT; ELICITOR; HAIRY ROOT CULTURE; INDOLE ALKALOID; JASMONIC ACID; LATE EXPONENTIAL PHASE; LOCHNERICINE; POLYGALACTURONASE; SECONDARY METABOLITE; SERPENTINE; TABERSONINE;

ENZYMES; GROWTH KINETICS; METABOLITES; ORGANIC ACIDS; PLANT CELL CULTURE; PLANTS (BOTANY); TISSUE;

CATHARANTHUS ROSEUS; ELICITOR DOSAGE; HAIRY ROOT CULTURE; INDOLE ALKALOIDS;

BIOSYNTHESIS;

ALKALOIDS; CULTURE TECHNIQUES; CYCLOPENTANES; INDOLES; PLANTS, MEDICINAL; POLYGALACTURONASE; TIME FACTORS;

CATHARANTHUS ROSEUS;

EID: 0032077393     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1021/bp980029v     Document Type: Article

References (43)

1. Aerts, R. J.; Gisi, D.; De Carolis, E.; De Luca, V. and Baumann. T. W. Methyl jasmonate vapor increases the developmentally controlled synthesis of alkaloids in Catharanthus and Cinchona seedlings. Plant J. 1994, 5, 635-643.
2. Alghisi, P.; Fayaron, F. Pectin-degrading enzymes arid plant-parasite interactions; Eur. J. Plant Pathol. 1995, 101, 365-375
3. Asada, M.; Shuler, M. L. Stimulation of ajmalicine production from Catharanthus roseus: effects of adsorption in situ, elicitors and alginate immobilization. Appl. Microbiol. Biotechnol. 1989, 30, 475-481.
4. Bhadra, R.; Shanks, J. V. Statistical design of the effect of inoculum conditions on growth of hairy root cultures of Catharanthus roseus. Biotechnol. Tech. 1995, 9, 681-680.
5. Bhadra, R.; Shanks, J. V. Transient studies of nutrient uptake, growth and indble alkaloid accumulation in heterotrophic cultures of hairy roots of Catharanthus roseus, Biotechnol. Bioeng. 1997, 55, 1-8.
6. Bhadra, R.; Ho, C. H.; Vani, S. N.; Shanks, J. V. Growth characteristics of hairy root lines of Catharanthus roseus. In Vitro 1991, 27, 290A.
7. Bhadra, R.; Vani, S. N.; Shanks, J. V. Production of indole alkaloids by selected hairy root lines of Catharanthus roseus. Biotchnol. Bioeng. 1993, 41, 581-592.
8. Cervone, F.; Hahn, M. G.; De Lorenzo, G.; Darvill, A. and Albersheim, P. Host pathogen Interactions XXXIIL. A plant protein converts a fungal pathogenesis factor into an elicitor of platnt defense response. Plant Physiol. 1989, 50, 542-548.
9. Ciddi, V.; Srinivasan, V.; Shuler, M. L. Elicitation,of Taxus sp. cell cultures for production of taxol. Biotechnol. Lett. 1995, 17, 1343-1346.
10. Collinge, D. B.; Susarenko, A. J. Plant gene expression in response to pathogens. Plant Mol. Biol. 1987, 9, 389-410.
11. Creelman, R. A.; Mullet, J. E. Jasmonic acid distribution and action in plants: Regulation during development and response to biotic and abiotic stress. Proc. Natl. Acad. Sci. U.S.A. 1995, 92, 4114-4119.
12. DiCosmp, F.; Misawa, M. Plant cell and tissue culture: Alternatives for metabolite production. Biotechnol. Adv. 1995, 13, 425-453.
13. Eilert, U.; Constabel, F.; Kurz, W. G. W. Elicitor-stimulation of monoterpene indole alkaloid in suspension cultures of Catharanthus roseus. J. Plant Physiol. 1986, 126, 11-22.
14. Farmer, E. E. Fatty acid signalling in plants and their associated microorganisms. Plant Mol. Biol. 1994, 26, 1423-1437.
15. Garnier, F.; Depierreux, C.; Petit-Pally, G.; Hamdi, S.; Chenieux, J.; Rideau, M. Induction of the accumulation of tryptamine and phenols by endogenous elicitors in cell suspension cultures of periwinkle. J. Plant Physiol. 1996, 148, 701-706.
16. Gundlach, H.; Müller, M. J.; Kutchan, T. M.; Zenk, M. H. Jasmonic acid as a signal transducer in elicitor-induced plant cell cultures. Proc. Natl Acad. Sci. U.S.A. 1992, 89, 2389- 2393.
17. Slung, K. H.; Kwak, S. S.; Kim, S. W.; Choi, C. W.; Liu, J. R. Improvement in the catharanthine productivity in hairy root cultures of Catharanthus roseus by using monosaccharides as a carbon source. Biotechnol. Lett. 1992, 14, 695-700.
18. Kutchan, T. M. Alkaloid biosynthesis - The basis for metabolic engineering of medicinal plants. Plant Cell 1995, 7, 1059- 1070.
19. Meijer, A. H.; Verpoorte, R.; Hoge, H. C. Regulation of enzymes and genes involved in terpenoid indole alkaloid biosynthesis in Catharanthus roseus. J. Plant Res. 1993 (Special Issue 3), 145-164.
20. Moreno, P. R. H.; van der Heiden, R.; Verpoorte, R. Cell and tissue cultures of Catharanthus roseus: A literature Survey II Plant Cell Tiss. Organ Cult. 1995, 42, 1-25.
21. Moreno, P. R. H.; Poulsen, C.; van der Heijden, R.; Verpoorte, R. Effects of elicitation on different metabolic pathways in Catharanthus roseus (L.)(J.Don cell suspension cultures. Enzyme Microb. Technol. 1996, 18, 99-107.
22. Mukundan, U.; Hjorsoto, M. A. Effect of fungal elicitor on thiophene production in hairy root culture of Tagetes patula. Appl. Microbiol. Biotechnol. 1990, 33 145-147.
23. Müller, M. J.; Bordschelm W.; Spannagl, E.; Zenk, M. H. Signaling in the elicitation process is mediated through; the octadecanoid pathwayf leading to Jasmonic acid. Proc. Natl. Acad. Sci. U.S.A. 1993, 90, 7490-7494.
24. Negeral, J.; Javelle, F. Induction of phenylpropanoid and tyramine metabolism in pectinase- or pronase-elicited cell suspension cultures of tobacco. Physiol. Plant. 1985, 95, 569-574.
25. Nojiri, H.; Yamane, H.; Nishimura, Y.; Yamada, A.; Shibuya, N.; Kodama, O.; Murofushi, N.; Omori, T. Involvement of Jasmonic acidi in elicitor-induced phytoalexin production in suspension-cultured rice cells Plant physiol. 1996, 110, 387- 392.
26. Parr, A. J.; Peerless, A. C. J.; Hamill, J. D.; Walton, N. J.; Robins, R. J.; Rhodes, M. J. C. Alkaloid production by transformed root culturesi of Catharanthus roseus. Plant Cell Rep. 1988, 7, 309-312.
27. Fasquali, G.; Goddijn, O. J. M.; Waal, A.; Verpoorte, R.; Schilperoort, R. A.; Hoge, J. H. C.; Memelink, J. Coordinated regulation of two indole alkaloid biosynthetic genes from Catharanthus roseus by auxin and elicitors. Plant Mol. Biol. 1992, 18, 1121-1131.
28. Rijhwani, S. K.; Shanks, J. V. Effect of subculture cycle on growth and indole alkaloid accumulation by Catharanthus roseus hairy root cultures. Enzyme Microb. Technol. 1998, in press.
29. Robertson, D.; McCormack, B.; Bolwell, G. P. Cell wall polysaccharide biosynthesis and related metabolism in elicitor-stressed cells of French bean (Phaseolus vulgaris L.). Biochem. J. 1995, 306, 745-750.
30. Roewer, I. A.; Cloutier, N.; Nessler, C. L.; Be luca, V. Transient induction of tryptophan decarboxylase and strictosidine synthase in cell suspension cultures of Catharanthus roseus. Plant Cell Rep. 1992, 11, 86-89.
31. Schripsema, J.; Dagnino, D.; Dos Santos, R. I.; Verpoorte, R. Breakdown of indole alkaloids in suspension cultures of Tabernaemontana divaritica and Catharanthus roseus. Plant Cell Tiss. Organ Cult. 1994, 35, 299-305.
32. Seitz, H. U.; Eilert, U.; De Luca, V.; Kurz, W. G. W. Elicitor mediated induction of phenylalanine ammonia lyase and tryptophan decarboxylase: Accumulation of phenols and indole alkaloids in cell suspension cultures of Catharanthus roseus. Plant Cell Tiss. Organ Cult. 1989, 18, 71-78.
33. Sim, S. J.; Chang, H. N.; Liu, J. R.; Jung, K. H. Production and secretion of indole alkaloids in hairy root cultures of Catharanthus roseus: Effects of in situ adsorption, fungal elicitation and permeabilization. J. Perm. Bio. 1994, 78, 229-234.
34. Singh, G.; Reddy, G. R.; Curtis, W. R. Use of binding measurements to predict elicitor dosage requirements for secondary metabolite production from root cultures. Biotechnol. Prog., 1994, 10, 365-371.
35. Srinivasan, V.; Ciddi, V.; Bringi, V.; Shuler, M. L. Metabolic inhibitors, elicitors and precursors as tools for probing yield limitation in taxane production by Taxus chinensis cell cultures. Biotechnol. Prog. 1996, 12, 457-465.
36. Toivonen, L.; Balsevich, J.; Kurz, W. G. W. Indole alkaloid production by hairy root cultures of Catharanthus roseus. Plant Cell Tiss. Organ Cult. 1989, 18, 79-93.
37. van der Heijden, R.; Verpoorte, R.; ten Hoopen, H. J. G. Cell and tissue cultures of Catharanthus roseus(L.) G. Don: a literature survey. Plant Cell Tiss. Organ Cult. 1989, 18, 231-280.
38. Vani, S. N. Bioreactor design for scaleup of Catharanthus roseus hairy root cultures for production of alkaloids alkaloids. Ph.D. Thesis, Rice University, 1996.
39. Vazquez-Flota, F.; Moreno-Valenzuela, O.; Miranda-Ham, J. A.; Voello-Coello, J.; Loyola-Vargas, V. M. Catharanthine and ajmalicine synthesis in Catharanthus roseus hairy root cultures. Medium optimization and elicitation. Plant Cell Tiss. Organ Cult. 1994, 38, 273-279.
40. Whitehead, I. M.; Threlfall, D. R. Production of phytoalexins by plant tissue cultures. J. Biotechnol. 1992, 26, 63-81.
41. Yoshikawa, M.; Tsuda, M.; Takeuchi, Y. Resistance to Fungal Diseases in Transgnic Tobacco Plants. Expressing the Phytoalexin Elicitor-Releasing factor, β-1,3-Endoglucanase, from Soybean. Naturwissenschaften 1993a, 80, 417-420.
42. Yoshikawa, M.; Yamaoka, N.; Takeuchi, Y. Elicitor: Their significance and primary modes of action in the induction of plant defense reactions. Plant Cell Physiol. 1993b, 34, 1163-1173.
43. Yukimune, Y.; Tabata, H.; Higashi, Y.; Hara, Y. Methyl jasmonate-induced overproduction ofpaclitaxel and baccatin III in Taxus cell suspension cultures, Nat. Biotechnol. 1996, 14, 1129-1132.