New four-component Ugi-type reaction. Synthesis of 3-methyl-1-oxo-1,3,4,6, 11,11a-hexahydro-2H-pyrazino[1,2-b]isoquinoline-3-carboxamides

Heterocyclic Communications

Volumn 12, Issue 2, 2006, Pages 107-110

  Ilyn, Alexey P ^a   Trifilenkov, Andrey S ^b   Kovrigin, Denis I ^b   Yudin, Michail V ^b   Ivachtchenko, Alexandre V ^a  

^a Chemical Diversity Research Institute   (Russian Federation)

^b CHEMDIV INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33646845508     PISSN: 07930283     EISSN: None     Source Type: Journal    
DOI: 10.1515/HC.2006.12.2.107     Document Type: Article

References (18)

1. (a) F.A. Romero, S.V. Vodonick, K.R. Criscione, M.J. McLeish, G.L. Grunewald, J. Med. Chem. 47, 4483 (2004).
2. (b) A. Mihalyi, R. Gaspar, Z. Zalan, L. Lazar, F. Fulop, P.A. de Witte, Anticancer Res. 24, 1631 (2004).
3. (c) H. Kubota, A. Kakefuda, T. Watanabe, N. Ishii, K. Wada, N. Masuda, S. Sakamoto, S. Tsukamoto, J. Med. Chem. 46, 4728 (2003).
4. H. Singh, S. Sharma, R.N. Iyer, N. Anand, Ind. J. Chem. 1, 70 (1997).
5. A.K. Saxena, P.C. Jain, N. Anand, Ind. J. Chem. 3, 230 (1975).
6. N. Saito, N. Kawakami, E. Yamada, A. Kubo, Antibiotics Chem. Pharm. Bull. 35, 1493 (1989).
7. (a) A. Hätzelt, S. Laschat, P.G. Jones, J. Grunenberg, Eur. J. Org. Chem. 23, 3936 (2002).
8. (b) C.W. Ona, H.C. Lee, Austral. J. Chem. 43, 773 (1990).
9. (a) K. Illgen, S. Nerdinger, T. Fuchs, C. Friedrich, L. Weber, E. Herdtweck, Synlett 1, 53 (2004).
10. (b) I. Ugi, W. Horl, C. Hanusch, T. Schmid, E. Herdweek, Heterocycles 47, 985 (1998).
11. (a) S. Cho, G. Keum, S.B. Kang, S.Y. Han, Y. Kim, Mol. Divers. 6, 283 (2003).
12. (b) J. Zhang, A. Jacobson, J.R. Rusche, W. Herlihy, J. Org. Chem. 64, 1074 (1999).
13. (c) Y.B. Kim, E.H. Choi, G. Keum, S.B. Kang, D.H. Lee, H.Y. Koh, Y. Kim, Org. Lett. 3, 4149 (2001).
14. (d) B. Beck, G. Larbig, B. Mejat, M. Magnin-Lachaux, A. Picard, E. Herdtweck, A. Domling, Org. Lett. 5, 1047 (2003).
15. (e) J.-F. Cheng, M. Chen, T. Arrhenius, A. Nadzan, Tetrahedron Lett. 43, 6293 (2002).
16. A.P. Ilyn, A.S. Trifilenkov, J.A. Kuzovkova, S.A. Kutepov, A.V. Nikitin, A.V. Ivachtchenko, J. Org. Chem. 70, 1478 (2005).
17. A.P. Ilyn, J.A. Kuzovkova, V.V. Potapov, A.M. Shkirando, D.I. Kovrigin, S.E. Tkachenko, A.V. Ivachtchenko, Tetrahedron Lett. 46, 881 (2005).
18. R. Grigg, J. Idle, P. Mcmeekin, D. Vipond, J. Chem. Soc. Chem. Comun. 2, 49 (1987).