Use of a zinc fluorophore to measure labile pools of zinc in body fluids and cell-conditioned media

BioTechniques

Volumn 40, Issue 4, 2006, Pages 509-520

  Zalewski, Peter ^a   Truong Tran, Ai ^b   Lincoln, Stephen ^a   Ward, David ^a   Shankar, Anu ^c   Coyle, Peter ^d   Jayaram, Lata ^a   Copley, Andrew ^a   Grosser, Dion ^a   Murgia, Chiara ^e   Lang, Carol ^a   Ruffin, Richard ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b NORTHWESTERN UNIVERSITY   (United States)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^d INSTITUTE OF MEDICAL AND VETERINARY SCIENCE   (Australia)

^e Istituto Nazionale di Ricerca Alimenti e Nutrizione   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BODY FLUIDS; CELL CULTURE; DISEASES; SCANNING ELECTRON MICROSCOPY; ZINC;

DIABETES MELLITUS; FLUOROMETRIC ASSAY; HOMEOSTASIS; METALLOPROTEINS;

FLUOROPHORES;

BUFFER; CHELATING AGENT; METALLOPROTEIN; SERUM ALBUMIN; TOLUENESULFONAMIDE DERIVATIVE; UNCLASSIFIED DRUG; ZINC; ZINQUIN; FLUORESCENT DYE;

ANALYTIC METHOD; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASSAY; BODY FLUID; CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; FEMALE; FLUOROMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; SALIVA LEVEL; SPUTUM; ZINC BLOOD LEVEL; ZINC DEFICIENCY; ZINC URINE LEVEL; ANIMAL; C57BL MOUSE; CHEMISTRY; EVALUATION; METHODOLOGY; SPECTROFLUOROMETRY;

MUS;

ANIMALS; BODY FLUIDS; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; FLUORESCENT DYES; HUMANS; MICE; MICE, INBRED C57BL; SPECTROMETRY, FLUORESCENCE; ZINC;

EID: 33646842514     PISSN: 07366205     EISSN: None     Source Type: Journal    
DOI: 10.2144/06404RR02     Document Type: Article

References (34)

1. Danscher, G. 1996. The autometallographic zinc-sulphide method. A new approach involving in vivo creation of nanometer-sized zinc sulphide crystal lattices in zinc-enriched synaptic and secretory vesicles. Histochem. J. 28:361-373.
2. Frederickson, C.J. 2003. Imaging zinc: old and new tools. Sci. STKE. 182:pe18.
3. Frederickson, C.J. 1989. Neurobiology of zinc and zinc-containing neurons. Int. Rev. Neurobiol. 31:145-238.
4. Truong-Tran, A.Q., R.E. Ruffin, and P.D. Zalewski. 2001. The role of zinc in caspase activation and apoptotic cell death. Biometals 14:315-330.
5. Frederickson, C.J., J.Y. Koh, and A.I. Bush. 2005. The neurobiology of zinc in health and disease. Nat. Rev. Neurosci. 6:449-462.
6. Palmiter, R.D., T.B. Cole, and S.D. Findley. 1996. ZnT-2, a mammalian protein that confers resistance to zinc by facilitating vesicular sequestration. EMBO J. 15:1784-1791.
7. Bruinsma, J.J., T. Jirakulaporn, A.J. Muslin, and K. Kornfeld. 2002. Zinc ions and cation diffusion facilitator proteins regulate Ras-mediated signaling. Dev. Cell 2:567-578.
8. Sandstead, H.H. 1991. Zn(II) deficiency. A public health problem. Am. J. Dis. Child. 145:853-859.
9. Walker, C.F. and R.E. Black. 2004. Zinc and the risk for infectious disease. Annu. Rev. Nutr. 24:255-275.
10. Vallee, B.L. and K.H. Falchuk. 1993. The biochemical basis of zinc physiology. Physiol. Rev. 73:79-118.
11. Truong-Tran, A.Q., R.E. Ruffin, P.S. Foster, A.M. Koskinen, P. Coyle, J.C. Philcox, A.M. Rofe, and P.D. Zalewski. 2002. Altered zinc homeostasis and caspase-3 activity in murine allergic airway inflammation. Am. J. Respir. Cell Mol. Biol. 27:286-296.
12. Zalewski, P.D., A.Q. Truong-Tran, D. Grosser, L. Jayaram, C. Murgia, and R.E. Ruffin. 2005. Zinc metabolism in airway epithelium and airway inflammation: basic mechanisms and clinical targets. Pharmacol. Ther. 105:127-149.
13. Smith, K.T., M.L. Failla, and R.J. Cousins. 1979. Identification of albumin as the plasma carrier for zinc absorption by perfused rat intestine. Biochem. J. 184:627-633.
14. Wilkins, P.J., P.C. Grey, and I.E. Dreosti. 1972. Plasma zinc as an indicator of zinc status in rats. Br. J. Nutr. 27:113-120.
15. Ibs, K.H. and L. Rink. 2003. Zinc-altered immune function. J. Nutr. 133(Suppl 1):1452S-1456S.
16. Zalewski, P.D. 1996. Zinc and immunity: implications for growth, survival and function of lymphoid cells. J. Nutr. Immunol. 4:39-101.
17. Qian, W.J., J.L. Peters, G.M. Dahlgren, K.R. Gee, and R.T. Kennedy. 2004. Simultaneous monitoring of Zn2+ secretion and intracellular Ca2+ from islets and islet cells by fluorescence microscopy. BioTechniques 37:922-930.
18. 4 in mast cell granules: role in regulation of caspase activation and NF-κB translocation. J. Immunol. 172:7750-7760.
19. Ward, A.D., S.F. Lincoln, W.H. Betts, P.D. Zalewski, I.J. Forbes, I. Mahadevan, M. Kimber, and K. Hendrickson. 2000. Zinquin ester-a reagent for the investigation of the role of available Zn(II) in living systems, p. 995-998. In A.M. Roussel, R.A. Anderson, and A.E. Favier (Eds.), Trace Elements in Man and Animals. Kluwer Academic, New York.
20. Coyle, P., P.D. Zalewski, J.C. Philcox, I.J. Forbes, A.D. Ward, S.F. Lincoln, I. Mahadevan, and A.M. Rofe. 1994. Measurement of zinc in hepatocytes using a fluorescent probe, zinquin: relationship to metallothionein and intracellular zinc. Biochem. J. 303:781-786.
21. 2+ complexes. J. Am. Chem. Soc. 125:3889-3895.
22. Mahadevan, I.B, M.C. Kimber, S.F. Lincoln, E.R.T. Tiekink, A.D. Ward, W.H. Betts, I.J. Forbes, and P.D. Zalewski. 1996. The synthesis of zinquin ester and zinquin acid, zinc (II)-specific fluorescing agents for use in the study of biological zinc (II). Aust. J. Chem. 49:561-568.
23. Tang, Z.L., K. Wasserloos, C.M. St. Croix, and B.R. Pitt. 2001. Role of zinc in pulmonary endothelial cell response to oxidative stress. Am. J. Physiol. Lung Cell. Mol. Physiol. 281:L243-L249.
24. Tsuda, M., K. Imaizumi, T. Katayama, K. Kitagawa, A. Wanaka, M. Tohyama, and T. Takagi. 1997. Expression of zinc transporter gene, ZnT-1, is induced after transient forebrain ischemia in the gerbil. J. Neurosci. 17:6678-6684.
25. Lonnerdal, B., B. Hoffman, and L.S. Hurley. 1982. Zinc and copper binding proteins in human milk. Am. J. Clin. Nutr. 36:1170-1176.
26. Faure, H., A. Favier, M. Tripier, and J. Arnaud. 1990. Determination of the major zinc fractions in human serum by ultrafiltration. Biol. Trace Elem. Res. 24:25-37.
27. Foote, J.W. and H.T. Delves. 1984. Albumin bound and alpha 2-macroglobulin bound zinc concentrations in the sera of healthy adults. J. Clin. Pathol. 37:1050-1054.
28. Rowe, D.J. and D.J. Bobilya. 2000. Albumin facilitates zinc acquisition by endothelial cells. Proc. Soc. Exp. Biol. Med. 224:178-186.
29. Stewart, A.J., C.A. Blindauer, S. Berezenko, D. Sleep, and P.J. Sadler. 2003. Interdomain zinc site on human albumin. Proc. Natl. Acad. Sci. USA 100:3701-3706.
30. Chesters, J.K. and M. Will. 1981. Measurement of zinc flux through plasma in normal and endotoxin-stressed pigs and the effects of zinc supplementation during stress. Br. J. Nutr. 46:119-130.
31. Inagaki, K., N. Mikuriya, S. Morita, H. Haraguchi, Y. Nakahara, M. Hatiori, T. Kinosita, and H. Saito. 2000. Speciation of protein-binding zinc and copper in human blood serum by chelating resin pre-treatment and inductively coupled plasma mass spectrometry. Analyst 125:197-203.
32. Frieden, E. 1986. Perspectives on copper biochemistry. Clin. Physiol. Biochem. 4:11-19.
33. Masuoka, J., J. Hegenauer, B.R. Van Dyke, and P. Saltman. 1993. Intrinsic stoichiometric equilibrium constants for the binding of zinc(II) and copper(II) to the high affinity site of serum albumin. J. Biol. Chem. 268:21533-21537.
34. Kinlaw, W.B., A.S. Levine, J.E. Morley, S.E. Silvis, and C.J. McClain. 1983. Abnormal zinc metabolism in type II diabetes mellitus. Am. J. Med. 75:273-277.