A mechanism for the inactivation of Ca2+/calmodulin-dependent protein kinase II during prolonged seizure activity and its consequence after the recovery from seizure activity in rats in vivo

Neuroscience

Volumn 140, Issue 3, 2006, Pages 981-992

  Yamagata, Y ^a,b,c   Imoto, K ^a,b   Obata, K ^a  

^a NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

^b GRADUATE UNIVERSITY FOR ADVANCED STUDIES   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

autophosphorylation; Ca2+ overload; CaMKII clusters; CaMKII self association; kainic acid; status epilepticus

Indexed keywords

CALCINEURIN; CALCIUM; CALMODULIN DEPENDENT PROTEIN KINASE II; KAINIC ACID; UNCLASSIFIED DRUG; CALMODULIN-DEPENDENT PROTEIN KINASE II; CONVULSANT AGENT; PROTEIN KINASE (CALCIUM,CALMODULIN); THREONINE;

ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; BRAIN HOMOGENATE; CONTROLLED STUDY; EPILEPSY; FRACTIONATION; HIPPOCAMPUS; IN VIVO STUDY; MALE; NERVE CELL; NONHUMAN; PARIETAL LOBE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN LOCALIZATION; RAT; SEIZURE; ANIMAL; BRAIN; CALCIUM SIGNALING; CELL MEMBRANE; CELL MEMBRANE POTENTIAL; CHEMICALLY INDUCED DISORDER; CONVALESCENCE; DISEASE MODEL; DRUG EFFECT; ENZYME ACTIVATION; ENZYMOLOGY; EPILEPTIC STATE; METABOLISM; PATHOPHYSIOLOGY; PHOSPHORYLATION; PHYSIOLOGY; SOLUBILITY; WISTAR RAT;

ANIMALS; BRAIN; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM; CALCIUM SIGNALING; CELL MEMBRANE; CONVULSANTS; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; EPILEPSY; KAINIC ACID; MALE; MEMBRANE POTENTIALS; NEURONS; PHOSPHORYLATION; RATS; RATS, WISTAR; RECOVERY OF FUNCTION; SOLUBILITY; STATUS EPILEPTICUS; THREONINE;

EID: 33646814771     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2006.02.054     Document Type: Article

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