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1
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33746964396
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Obe T, Suehiro I, Morioka M, Ishii S, Tanaka H, Kadowaki S, Sekiya T ACS 1996 211th New Orleans MEDI 094
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Synthesis and SAR study of 5-{6-alkoxy-2-naphthalenyl)methyl2,4-thiazolidine-dione derivative as potent antihyperglycemic agent. Ueno H, Obe T, Suehiro I, Morioka M, Ishii S, Tanaka H, Kadowaki S, Sekiya T ACS 1996 211th New Orleans MEDI 094
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Synthesis and SAR Study of 5-{6-alkoxy-2-naphthalenylmethyl2,4-thiazolidine-dione Derivative As Potent Antihyperglycemic Agent.
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Ueno, H.1
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2
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33746963095
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Widdowson PS, Kadowaki S, Williams G BR J PHARMACOL 1997 122 Suppl 149P Reports the action of MCC-555 in Zucker and ZDF rats.
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Improved insulin sensitivity in Zucker and ZDF rats following chronic treatment with novel thiazolidinedione MCC-555. Upton R, Widdowson PS, Kadowaki S, Williams G BR J PHARMACOL 1997 122 Suppl 149P Reports the action of MCC-555 in Zucker and ZDF rats.
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Upton, R.1
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6
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0032484224
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Bailey ST, KrakowSL, Minami C, LazarMAetalJBIOL CHEM1998 273 49 32679 32684
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A potent antidiabetic thiazolidinedione with unique peroxisome proliferator-activated receptor -activating properties. Reginato MJ, Bailey ST, KrakowSL, Minami C, LazarMAetalJBIOL CHEM1998 273 49 32679 32684
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9
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33747007118
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UK. Bums T IDDB MEETING REPORT 1999 April 21 Defines the potency of MCC-555.
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Novel Drug Developments for NIDDM and Insulin Resistance IBC Conference London, UK. Bums T IDDB MEETING REPORT 1999 April 21 Defines the potency of MCC-555.
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11
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0033566136
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Bhushan V, Reddy AS, Rao PB, Reddy NJ, Harikishore P, Haritha N, Vikramaditiyan RK, Chakrabarti R, Rajagopalan R, Katneni K J MED CHEM 1999 42 14 2569 2581
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Novel euglycemic and hypolipidemic agents. 4. Pyridyl- and quinolinyl-containing thiazolidinediones. Lohray BB, Bhushan V, Reddy AS, Rao PB, Reddy NJ, Harikishore P, Haritha N, Vikramaditiyan RK, Chakrabarti R, Rajagopalan R, Katneni K J MED CHEM 1999 42 14 2569 2581
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Novel Euglycemic and Hypolipidemic Agents. 4. Pyridyl- and Quinolinyl-containing Thiazolidinediones.
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Lohray, B.B.1
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12
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33747018735
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Upton R, Ishii S, Williams G BR J PHARMACOL 1998 123 Proc Suppl 187P MCC-555 reduces OB expression, with no leptin modification.
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The thiazolidinedione, MCC-555, reduces OB expression in mature adipocytes, but does not alter plasma leptin concentrations. Widdowson PS, Upton R, Ishii S, Williams G BR J PHARMACOL 1998 123 Proc Suppl 187P MCC-555 reduces OB expression, with no leptin modification.
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The Thiazolidinedione, MCC-555, Reduces OB Expression in Mature Adipocytes, but Does Not Alter Plasma Leptin Concentrations.
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Widdowson, P.S.1
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13
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33747001745
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The thiazolidinedione, MCC-555, prevents nitric oxide synthase induction in the pancreas of the Zucker diabetic fatty rat Pickavance LC, Widdowson PS, Foster JR, Ishii S BRJ PHARMACOL 1999128 Proc Suppl 116P
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The Thiazolidinedione, MCC-555, Prevents Nitric Oxide Synthase Induction in the Pancreas of the Zucker Diabetic Fatty Rat Pickavance LC, Widdowson PS, Foster JR, Ishii S BRJ PHARMACOL 1999128 Proc Suppl 116P
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15
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0031728308
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Widdowson PS, King P, Ishii S, Tanaka H, Williams G BR J PHARMACOL 1998125 4 767 - 770
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The development of overt diabetes in young Zucker Diabetic Fatty (ZDF) rats and the effects of chronic MCC-555 treatment. Pickavance L, Widdowson PS, King P, Ishii S, Tanaka H, Williams G BR J PHARMACOL 1998125 4 767 - 770
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The Development of Overt Diabetes in Young Zucker Diabetic Fatty (ZDF) Rats and the Effects of Chronic MCC-555 Treatment.
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Pickavance, L.1
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16
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18544403720
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BIOORG MED CHEM LETT 1998 8 19 2725 - 2730 Clarifies the characteristics of these novel thiazolidinediones.
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Synthesis and biological activity of novel thiazolidinediones. Prabhakar C et al BIOORG MED CHEM LETT 1998 8 19 2725 - 2730 Clarifies the characteristics of these novel thiazolidinediones.
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Synthesis and Biological Activity of Novel Thiazolidinediones.
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Prabhakar, C.1
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17
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33746987494
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and their use in therapeutic approaches to insulin resistance.
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Therapeutic approaches to insulin resistance. Laight DW EXP OP/NTHERR4T20001011 1703-1709 Explains the nature and function of PPARy agonists, and their use in therapeutic approaches to insulin resistance.
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19
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33746981246
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Nakamura J, Hamada Y, Nakayama M, Chaya S, Komori H, Kiriyama T, Kasuya Y, Yasuda Y, Hotta N DIABETOLOGIA 2000 43 Suppl 1 A190 Explains the action of MCC-555 on hepatocytes.
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Acute effect of MCC-555 in isolated hepatocytes of Otsuka LongEvans Tokushima Fatty rats. Mizubayashi R, Nakamura J, Hamada Y, Nakayama M, Chaya S, Komori H, Kiriyama T, Kasuya Y, Yasuda Y, Hotta N DIABETOLOGIA 2000 43 Suppl 1 A190 Explains the action of MCC-555 on hepatocytes.
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Acute Effect of MCC-555 in Isolated Hepatocytes of Otsuka LongEvans Tokushima Fatty Rats.
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Mizubayashi, R.1
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25
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0034068059
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Davem TJ, Shakil AO, Schick L, Masharani U, Chow H, Preise C, Lee WM, Bass WM DIG DIS SCI 2000 45 3 549-553
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Troglitazone-induced fulminant hepatic failure. Acute Liver Failure Study Group. Murphy EJ, Davem TJ, Shakil AO, Schick L, Masharani U, Chow H, Preise C, Lee WM, Bass WM DIG DIS SCI 2000 45 3 549-553
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Troglitazone-induced Fulminant Hepatic Failure. Acute Liver Failure Study Group.
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Murphy, E.J.1
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26
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85120114398
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Amano S, Sato J, Yamamoto K, Adachi H, Okabe H, Fujiama Y, Bamba T Hum Path 2000 31 2 250-253
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Subacute hepatic failure associated with a new antidiabetic agent, troglitazone: a case report with autopsy examination. Fukano M, Amano S, Sato J, Yamamoto K, Adachi H, Okabe H, Fujiama Y, Bamba T Hum Path 2000 31 2 250-253
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Subacute Hepatic Failure Associated with A New Antidiabetic Agent, Troglitazone: A Case Report with Autopsy Examination.
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Fukano, M.1
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Goldstein BJINTJ CLIN PRACT2000 54 5 333-337
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Rosiglitazone. Goldstein BJINTJ CLIN PRACT2000 54 5 333-337
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Rosiglitazone.
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30
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33746949285
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disposition, and metabolism of rostglitazone, a potent thiazolidinedione insulin sensitizer, in humans. Cox PJ, Ryan DA, Mollis FJ, Harris AM, Miller AK, Vousden M, Cowley H DRUG METAB DISPOS 2000 174287-294
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Absorption, disposition, and metabolism of rostglitazone, a potent thiazolidinedione insulin sensitizer, in humans. Cox PJ, Ryan DA, Mollis FJ, Harris AM, Miller AK, Vousden M, Cowley H DRUG METAB DISPOS 2000 174287-294
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33746979707
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Oe T, Suehiro I, Nakamura F MITSUBISHI-TOKYO PHARMACEUTICALS EP-00604983 1996
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Naphthalene derivatives. Ueno H, Oe T, Suehiro I, Nakamura F MITSUBISHI-TOKYO PHARMACEUTICALS EP-00604983 1996
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Naphthalene Derivatives.
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Ueno, H.1
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