Light chain inclusion permits terminal B cell differentiation and does not necessarily result in autoreactivity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 20, 2006, Pages 7747-7752

  Sirac, C ^a   Carrion, C ^a   Duchez, S ^a   Comte, I ^a   Cogne M ^a,b  

^a UNIVERSITY OF LIMOGES   (France)

^b CNRS   (France)

Author keywords

Antibodies; Autoimmunity; B lymphocytes; Gene regulation

Indexed keywords

AUTOANTIBODY; HYBRID PROTEIN; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN J CHAIN; IMMUNOGLOBULIN KAPPA CHAIN; IMMUNOGLOBULIN KAPPA DELTA CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBODY PRODUCTION; ANTIBODY SECRETING CELL; ARTICLE; AUTOIMMUNITY; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; B LYMPHOCYTE DIFFERENTIATION; CELL MATURATION; CELL SELECTION; CLONAL SELECTION; CONTROLLED STUDY; GENE CONTROL; GENE EXPRESSION; GENE KNOCK IN; GENE REARRANGEMENT; GENETIC SELECTION; HEMIZYGOSITY; HOMOZYGOSITY; HUMAN; HUMAN CELL; HYBRID; IMMUNOGLOBULIN VARIABLE REGION; LYMPHOCYTE FUNCTION; MOUSE; MOUSE MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; STOCHASTIC MODEL; TRANSGENE;

ANIMALS; AUTOANTIBODIES; B-LYMPHOCYTES; CELL DIFFERENTIATION; CELL LINEAGE; GENE REARRANGEMENT, B-LYMPHOCYTE, LIGHT CHAIN; HUMANS; HYBRIDOMAS; IMMUNOGLOBULIN KAPPA-CHAINS; IMMUNOGLOBULIN LAMBDA-CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; MICE; MICE, TRANSGENIC; MULTIGENE FAMILY; RECOMBINANT FUSION PROTEINS; SPLEEN; TRANSGENES;

ANIMALIA;

EID: 33646734489     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0509121103     Document Type: Article

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