Dichotomous effect of aerosolized hyaluronan in a hamster model of endotoxin-induced lung injury

Experimental Lung Research

Volumn 31, Issue 9-10, 2005, Pages 807-818

  Nadkarni, Priya P ^b   Kulkarni, Girish S ^b   Cerreta, Joseph M ^b   Ma, Shuren ^b   Cantor, Jerome O ^a  

^a ST JOHN'S UNIVERSITY   (United States)

^b NONE

Author keywords

Anti inflammatory; Endotoxin; Hyaluronan; Inflammation; Lung

Indexed keywords

ENDOTOXIN; HYALURONIC ACID;

AEROSOL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE EXACERBATION; DISEASE MODEL; HAMSTER; INHALATION; LABORATORY DIAGNOSIS; LUNG EMPHYSEMA; LUNG INJURY; MOLECULAR WEIGHT; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL;

AEROSOLS; ANIMALS; APOPTOSIS; CRICETINAE; ENDOTOXINS; HYALURONIC ACID; LUNG; MESOCRICETUS; NEUTROPHILS; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I;

EID: 33646685257     PISSN: 01902148     EISSN: 15210499     Source Type: Journal    
DOI: 10.1080/01902140600574942     Document Type: Article

References (30)

1. Suki B, Lutchen KR, Ingenito EP: On the progressive nature of emphysema: roles of proteases, inflammation, and mechanical forces. Am J Respir Crit Care Med. 2003;168:516-521.
2. Barnes PJ, Shapiro SD, Pauwels RA: Chronic obstructive pulmonary disease: molecular and cellular mechanisms. Eur Respir J. 2003;22:672-678.
3. Hogg JC, Senior RM: Chronic obstructive pulmonary disease c2: pathology and biochemistry of emphysema. Thorax. 2002;57:830-834.
4. Shapiro SD: Proteinases in chronic obstructive pulmonary disease. Biochem Soc Trans. 2002;30:98-102.
5. Petty TL: COPD in perspective. Chest. 2002;121 (Suppl):116S-120S.
6. Abboud RT, Ford GT, Chapman KR: Emphysema in alpha1-antitrypsin deficiency: does replacement therapy affect outcome? Treat Respir Med. 2005;4:1-8.
7. Churg A, Wright JL: Proteases and emphysema. Curr Opin Pulm Med. 2005;11:153-159.
8. Cantor JO, Shteyngart B, Cerreta JM, Armand G, Liu M, Turino GM: The effect of hyaluronan on elastic fiber injury in vitro and elastase-induced airspace enlargement in vivo. Proc Soc Exp Biol Med. 2000;225:65-71.
9. Cantor JO, Cerreta JM, Armand G, Turino GM: Aerosolized hyaluronic acid decreases alveolar injury induced by human neutrophil elastase. Proc Soc Exp Biol Med. 1998;217:471-475.
10. Cantor JO, Cerreta JM, Armand G, Turino GM: Further investigation of the use of intratracheally administered hyaluronic acid to ameliorate elastase-induced emphysema. Exp Lung Res. 1997;23:229-244.
11. Cantor JO, Cerreta JM, Keller S, Turino GM: Modulation of airspace enlargement in elastase-induced emphysema by intratracheal instillment of hyaluronidase and hyaluronic acid. Exp Lung Res. 1995;21:423-436.
12. Bai KJ, Spicer AP, Mascarenhas MM, Yu L, Ochoa CD, Garg HG, Quinn DA: The role of hyaluronan synthase 3 in ventilator-induced lung injury. AmJ Respir Crit Care Med. 2005;172:92-98.
13. Mascarenhas MM, Day RM, Ochoa CD, Choi WI, Yu L, Ouyang B, Garg HG, Hales CA, Quinn DA: Low molecular weight hyaluronan from stretched lung enhances interleukin-8 expression. Am J Respir Cell Mol Biol. 2004;30:51-60.
14. Horton MR, Shapiro S, Bao C, Lowenstein CJ, Noble PW: Induction and regulation of macrophage metalloelastase by hyaluronan fragements in mouse macrophages. J Immunol. 1999;162:4171-4176.
15. McKee CM, Penno MB, Cowman M, Burdick MD, Strieter RM, Bao C, Noble PW: Hyaluronan (HA) fragments induce chemokine gene expression in alveolar macrophages. The role of HA size and CD44. J Clin Invest. 1996;98:2403-2413.
16. Yasui S, Nagai A, Aoshiba K, Ozawa Y, Kakuta Y, Konno K: A specific neutrophil elastase inhibitor (ONO-5046.Na) attenuates LPS-induced acvite lung inflammation in the hamster. Eur Respir J. 1995;8:1293-1299.
17. Szarka RJ, Wang N, Gordon L, Nation PN, Smith RH: A murine model of pulmonary damage induced by lipopolysaccharide via intranasal instillation. J Immunol Methods. 1997;202:49-57.
18. Cantor JO, Cerreta JM, Ochoa M, Ma S, Chow T, Grunig G, Turino GM: Aerosolized hyaluronan limits airspace enlargement in a mouse model of cigarette smoke-induced pulmonary emphysema. Exp Lung Res. 2005;31:417-430.
19. Cantor JO, Cerreta JM, Armand G, Keller S, Turino GM: Pulmonary air-space enlargement induced by intratracheal instillment of hyaluronidase and concomitant exposure to 60% oxygen. Exp Lung Res. 1993;19:177-192.
20. Alstergren P, Zhu B, Glougauer M, Mak TW, Ellen RP, Sodek J: Polarization and directed migration of murine neutrophils is dependent on cell surface expression of CD44. Cell Immunol. 2004;231:146-157.
21. Khan AI, Kerfoot SM, Heit B, Liu L, Andonegui G, Ruffell B, Johnson P, Kubes P: Role of CD44 and hyaluronan in neutrophil recruitment. J Immunol. 2004;173:7594-7601.
22. Kipnis A, Basaraba RJ, Turner J, Orme IM: Increased neutrophil influx but no impairment of protective immunity to tuberculosis in mice lacking the CD44 molecule. J Leukoc Biol. 2003;74:992-997.
23. Wang Q, Teder P, Judd NP, Noble PW, Doerschuk CM: CD44 deficiency leads to enhanced neutrophil migration and lung injury in Escherichia coli pneumonia in mice. Am J Pathol. 2002;161:2219-2228.
24. Calkins CM, Heimbach JK, Bensard DD, Song Y, Raeburn CD, Meng X, McIntyre RC Jr: TNF receptor I mediates chemokine production and neutrophil accumulation in the lung following systemic lipopolysaccharide. J Surg Res. 2001;101:232-237.
25. Alikhani M, Alikhani Z, Graves DT: Apoptotic effects of LPS on fibroblasts are indirectly mediated through TNFR1. J Dent Res. 2004;83:671-676.
26. Mummert ME, Mohamadzadeh M, Mummert DI, Mizumoto N, Takashima A: Development of a peptide inhibitor of hyaluronan-mediated leukocyte trafficking. J Exp Med. 200;192:769-779.
27. Scuri M, Abraham WM, Botvinnikova Y, Forteza R: Hyaluronic acid blocks porcine pancreatic elastase (PPE)-induced bronchocontriction in sheep. Am J Respir Crit Care Med. 2001;164:1855-1859.
28. Alam CA, Seed MP, Freemantle C, Brown J, Perretti M, Carrier M, Divwedi A, West DC, Gustafson S, Colville-Nash PR, Willoughby DA: The inhibition of neutrophil-endothelial cell adhesion by hyaluronan independent of CD44. Inflammopharmacology. 2005;12:535-550.
29. Scott JE, Cummings C, Brass A, Chen Y: Secondary and tertiary structures of hyaluronan in aqueous solution, investigated by rotary shadowing-electron microscopy and computer simulation. Hyaluronan is a very efficient network-forming polymer. Biochem J. 1991;274:699-705.
30. Moreland LW: Intra-articular hyaluronan (hyaluronic acid) and hylans for the treatment of osteoarthritis: mechanisms of action. Arthritis Res Ther. 2003;5:54-67.