Spectroscopic and DNA-binding characterization of the isolated heme-bound basic helix-loop-helix-PAS-A domain of neuronal PAS protein 2 (NPAS2), a transcription activator protein associated with circadian rhythms

FEBS Journal

Volumn 273, Issue 11, 2006, Pages 2528-2539

  Mukaiyama, Yuji ^a   Uchida, Takeshi ^b,c   Sato, Emiko ^a   Sasaki, Ai ^a   Sato, Yuko ^a   Igarashi, Jotaro ^a   Kurokawa, Hirofumi ^a   Sagami, Ikuko ^a,d   Kitagawa, Teizo ^b   Shimizu, Toru ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b OKAZAKI INSTITUTE FOR INTEGRATIVE BIOSCIENCE   (Japan)

^c HOKKAIDO UNIVERSITY   (Japan)

^d KYOTO PREFECTURAL UNIVERSITY   (Japan)

Author keywords

Circadian rhythms; DNA binding; Heme sensor protein; PAS domain; Resonance Raman spectroscopy

Indexed keywords

DNA; FERRIC ION; HEME; IRON COMPLEX; NEURONAL PAS PROTEIN 2; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ABSORPTION SPECTROPHOTOMETRY; AMINO TERMINAL SEQUENCE; ARTICLE; CIRCADIAN RHYTHM; DNA BINDING; E BOX ELEMENT; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PURIFICATION; RAMAN SPECTROMETRY;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CHROMATOGRAPHY, GEL; CIRCADIAN RHYTHM; DNA; HEME; KINETICS; MICE; NERVE TISSUE PROTEINS; NEURONS; PLASMIDS; PROTEIN BINDING; RECOMBINANT PROTEINS; SPECTROPHOTOMETRY; SPECTRUM ANALYSIS, RAMAN; TRANS-ACTIVATORS;

EID: 33646682128     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2006.05259.x     Document Type: Article

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