Arachidonic acid induces ERK activation via Src SH2 domain association with the epidermal growth factor receptor

Kidney International

Volumn 69, Issue 10, 2006, Pages 1823-1832

  Alexander, L D ^a   Ding, Y ^b   Alagarsamy, S ^b   Cui, X L ^b   Douglas, J G ^b  

^a UNIVERSITY OF MICHIGAN DEARBORN   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Angiotensin II; Arachidonic acid; c Src; EGF receptor transactivation; Mitogen activated protein (MAP) kinase

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; 4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; AGAROSE; ANGIOTENSIN 2 RECEPTOR; ANGIOTENSIN II; ARACHIDONIC ACID; ARACHIDONIC ACID DERIVATIVE; EPIDERMAL GROWTH FACTOR RECEPTOR; FATTY ACID; FLUOROPHOSPHATE; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; ICOSATETRAENOIC ACID; MEPACRINE; METHYL ARACHIDONYL FLUOROPHOSPHATE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOLIPASE A2; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARACHIDONIC ACID METABOLISM; ARTICLE; BIOASSAY; CELL CULTURE; CONJUGATE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; GENE REPRESSION; IMMUNOBLOTTING; IMMUNOCOMPLEX KINASE ASSAY; KIDNEY PROXIMAL TUBULE; NONHUMAN; ONCOGENE SRC; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; RABBIT; RECEPTOR BINDING; RECEPTOR BLOCKING; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAIN; SRC HOMOLOGY DOMAIN 2; TRANSACTIVATION; WESTERN BLOTTING;

ANGIOTENSIN II; ANIMALS; ARACHIDONIC ACID; CELLS, CULTURED; CULTURE MEDIA, SERUM-FREE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; GLUTATHIONE TRANSFERASE; KIDNEY TUBULES, PROXIMAL; KINETICS; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS PP60(C-SRC); PYRIMIDINES; RABBITS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECOMBINANT FUSION PROTEINS; TRANS-ACTIVATION (GENETICS); TYRPHOSTINS;

EID: 33646674670     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/sj.ki.5000363     Document Type: Article

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