Cryoprotection mechanisms of polyethylene glycols on lactate dehydrogenase during freeze-thawing

AAPS Journal

Volumn 6, Issue 3, 2004, Pages

  Mi, Yanli ^a   Wood, George ^b   Thoma, Laura ^b  

^a PFIZER INC   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

14C PEG 4000 binding; Circular dichroism (CD); Freeze thaw; Lactate dehydrogenase (LDH); SDS PAGE

Indexed keywords

CARBON 14; LACTATE DEHYDROGENASE; MACROGOL; MACROGOL 400; MACROGOL 8000; CRYOPROTECTIVE AGENT; MACROGOL DERIVATIVE;

ARTICLE; CIRCULAR DICHROISM; CONCENTRATION RESPONSE; CONTROLLED STUDY; CRYOPROTECTION; CRYSTALLIZATION; ENZYME ACTIVITY; FREEZE THAWING; GEL FILTRATION; ISOTOPE LABELING; MOLECULAR WEIGHT; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN SECONDARY STRUCTURE; ULTRAVIOLET RADIATION; ANIMAL; DRUG EFFECT; FREEZING; RABBIT;

ANIMALS; CRYOPROTECTIVE AGENTS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FREEZING; L-LACTATE DEHYDROGENASE; POLYETHYLENE GLYCOLS; RABBITS;

EID: 33646650431     PISSN: 15221059     EISSN: 15221059     Source Type: Journal    
DOI: 10.1208/aapsj060322     Document Type: Article

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