Hyperoxic ventilation increases the tolerance of acute normovolemic anemia in anesthetized pigs

Critical Care Medicine

Volumn 34, Issue 5, 2006, Pages 1475-1482

  Pape, A ^a   Meier, J ^a   Kertscho, H ^a   Steche, M ^a   Laout, M ^a   Schwerdel, F ^a   Wedel, M ^a   Zwissler, B ^a   Habler, O ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

Acute normovolemic anemia; Blood; Critical hemoglobin concentration; Hyperoxic ventilation; Oxygen transport; Transfusion

Indexed keywords

HEMOGLOBIN; HETASTARCH; METHEMOGLOBIN; OXYGEN;

ANEMIA; ANIMAL EXPERIMENT; ARTICLE; BLOOD TRANSFUSION; BLOOD VOLUME; CELL FREE SYSTEM; CONTROLLED STUDY; HEART FUNCTION; HYPEROXIA; LUNG VENTILATION; NONHUMAN; OXYGEN CONSUMPTION; OXYGEN TRANSPORT; PRIORITY JOURNAL; PROPHYLAXIS; PROSPECTIVE STUDY; RISK BENEFIT ANALYSIS; SWINE; TISSUE OXYGENATION; ANIMAL; BLEEDING; BLOOD; EVALUATION; HEMODILUTION; HEMODYNAMICS; METABOLISM; OXYGEN THERAPY; PATHOPHYSIOLOGY; RANDOMIZATION;

ANEMIA; ANIMALS; BLOOD LOSS, SURGICAL; BLOOD VOLUME; HEMODILUTION; HEMODYNAMIC PROCESSES; HEMOGLOBINS; OXYGEN; OXYGEN CONSUMPTION; OXYGEN INHALATION THERAPY; PROSPECTIVE STUDIES; RANDOM ALLOCATION; SWINE;

EID: 33646591523     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000215826.45839.36     Document Type: Article

References (34)

1. Goodnough LT: Risks of blood transfusion. Crit Care Med 2003; 31:S678-S686
2. Habler O: Cardiac high-risk patients: From "permissive" to "deliberate" anemia. Crit Care Med 2005; 33:2434-2435
3. Messmer KF: Acceptable hematocrit levels in surgical patients. World J Surg 1987; 11:41-46
4. Hebert PC, Fergusson DA, Slather D, et al: Revisiting transfusion practices in critically ill patients. Crit Care Med 2005; 33:7-12
5. Habler OP, Messmer KF: The physiology of oxygen transport. Transfus Sci 1997; 18:425-435
6. Schumacker PT, Cain SM: The concept of a critical oxygen delivery. Intensive Care Med 1987; 13:223-229
7. Meier JM, Kemming GI, Kisch-Wedel H, et al: Hyperoxic ventilation reduces 6-hour mortality at the critical hemoglobin concentration. Anesthesiology 2004; 100:70-76
8. Meier JM, Kemming GI, Kisch-Wedel H, et al: Hyperoxic ventilation reduces six-hour mortality after partial fluid resuscitation from hemorrhagic shock. Shock 2004; 22:240-247
9. Meier JM, Pape A, Lauscher P, et al: Hyperoxia in lethal methemoglobinemia - Effects on oxygen transport, tissue oxygenation and survival in pigs. Crit Care Med 2005; 33:1582-1588
10. 2-decline. Comput Biol Med 2003; 33:395-405
11. Haller M, Akbulut C, Brechtelsbauer H, et al: Determination of plasma volume with indocyanine green in man. Life Sci 1993; 53:1597-1604
12. Kessler M, Hoper J, Krumme BA: Monitoring of tissue perfusion and cellular function. Anesthesiology 1976; 45:184-197
13. Fontana JL, Welborn L, Mongan PD, et al: Oxygen consumption and cardiovascular function in children during profound intraoperative normovolemic hemodilution. Anesth Analg 1995; 80:219-225
14. Zollinger A, Hager P, Singer T, et al: Extreme hemodilution due to massive blood loss in tumor surgery. Anesthesiology 1997; 87:985-987
15. van der Linden P, De Hert S, Mathieu N, et al: Tolerance to acute isovolemic hemodilution. Effect of anesthetic depth. Anesthesiology 2003; 99:97-104
16. Ickx BE, Rigolet M, van der Linden P: Cardiovascular and metabolic response to acute normovolemic anemia. Effects of anesthesia. Anesthesiology 2000; 93:1011-1016
17. Perez-de-Sa V, Roscher R, Cunha-Goncalves D, et al: Mild hypothermia has minimal effects on the tolerance to severe progressive normovolemic anemia in Swine. Anesthesiology 2002; 97:1189-1197
18. 2. Minerva Anestesiol 1999; 65:393-396
19. Harder DR, Narayanan J, Birks EK, et al: Identification of a putative microvascular oxygen sensor. Circ Res 1996; 79:54-61
20. Heyman SN, Goldfarb M, Darmon D, et al: Tissue oxygenation modifies nitric oxide bioavailability. Microcirculation 1999; 6:199-203
21. Habler OP, Kleen MS, Kemming GI, et al: Hyperoxia in extreme hemodilution. Eur Surg Res 2002; 34:181-187
22. Habler OP, Messmer KF: Hyperoxaemia in extreme haemodilution. Br J Anaesth 1998; 81(Suppl 1):79-82
23. Zenri H, Rodriquez-Capote K, McCaig L, et al: Hyperoxia exposure impairs surfactant function and metabolism. Crit Care Med 2004; 32:1155-1160
24. 2. J Basic Clin Physiol Pharmacol 1994; 5:67-87
25. Tahepold P, Valen G, Starkopf J, et al: Pretreating rats with hyperoxia attenuates ischemia-reperfusion injury of the heart. Life Sci 2001; 68:1629-1640
26. Kemming GI, Meisner FG, Kleen MS, et al: Hyperoxic ventilation at the critical haematocrit. Resuscitation 2003; 56:289-297
27. Habler OP, Kleen MS, Hutter JW, et al: Effects of hyperoxic ventilation on hemodilution-induced changes in anesthetized dogs. Transfusion 1998; 38:135-144
28. Hameed SM, Aird WC, Cohn SM: Oxygen delivery. Crit Care Med 2003; 31:S658-S667
29. Wettstein R, Tsai AG, Erni D, et al: Improving microcirculation is more effective than substitution of red blood cells to correct metabolic disorder in experimental hemorrhagic shock. Shock 2004; 21:235-240
30. Moudgil R, Michelakis ED, Archer SL: Hypoxic pulmonary vasoconstriction. J Appl Physiol 2005; 98:390-403
31. Holt JP, Rhode EA, Kines H: Ventricular volumes and body weight in mammals. Am J Physiol 1968; 215:704-715
32. van Woerkens EC, Trouwborst A, van Lanschot JJ: Profound hemodilution: What is the critical level of hemodilution at which oxygen delivery-dependent oxygen consumption starts in an anesthetized human? Anesth Analg 1992; 75:818-821
33. Cain SM: Oxygen delivery and uptake in dogs during anemic and hypoxic hypoxia. J Appl Physiol 1977; 42:228-234
34. Meisner FG, Kemming GI, Habler OP, et al: Diaspirin crosslinked hemoglobin enables extreme hemodilution beyond the critical hematocrit. Crit Care Med 2001; 29:829-838