Hyperoxia exposure impairs surfactant function and metabolism

Critical Care Medicine

Volumn 32, Issue 5, 2004, Pages 1155-1160

  Zenri, Hiromi ^a   Rodriquez Capote, Karina ^a   McCaig, Lynda ^a   Yao, Li Juan ^a   Brackenbury, Angela ^a   Possmayer, Fred ^b   Veldhuizen, Ruud ^a   Lewis, Jim ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b Dept of Physiology and Pharmacology St Joseph's Health Centre University of Western Ontario ^*

Author keywords

Acute lung injury; Aggregates; Surface tension

Indexed keywords

OXYGEN; PROTEIN;

ADULT RESPIRATORY DISTRESS SYNDROME; AMBIENT AIR; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; EVALUATION; HYPEROXIA; IN VITRO STUDY; LIPID PEROXIDATION; LUNG ALVEOLUS SURFACE TENSION; LUNG COMPLIANCE; LUNG DISEASE; LUNG FUNCTION; LUNG INJURY; LUNG LAVAGE; MALE; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; OXYGEN BREATHING; PRESSURE VOLUME CURVE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN ISOLATION; PROTEIN METABOLISM; RAT; RAT STRAIN; TECHNIQUE; TISSUE LEVEL;

EID: 2442542400     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000126264.00551.C8     Document Type: Article

References (37)

1. Bernard GR, Artigas A, Brigham KL, et al: The American-European consensus conference on ARDS: Definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med 1994; 149: 818-824
2. Artigas A, Bernard GR, Carlet J, et al: The American-European Consensus Conference on ARDS, part 2: Ventilatory, pharmacologic, supportive therapy, study design strategies, and issues related to recovery and remodeling. Acute respiratory distress syndrome. Am J Respir Crit Care Med 1998; 157: 1332-1347
3. Villar J, Slutsky AS: The incidence of the adult respiratory distress syndrome. Am Rev Respir Dis 1989; 140:814-816
4. Livingston DH, Mosenthal AC, Deitch EA: Sepsis and multiple organ dysfunction syndrome: A clinical-mechanistic overview. New Horiz 1995; 3:257-264
5. Lewis JF, Veldhuizen R: The role of exogenous surfactant in the treatment of acute lung injury. Annu Rev Physiol 2003; 65: 613-642
6. Frerking I, Gunther A, Seeger W, et al: Pulmonary surfactant: Functions, abnormalities and therapeutic options. Intensive Care Med 2001; 27:1699-1717
7. Malloy J, McCaig L, Veldhuizen R, et al: Alterations of the endogenous surfactant system in septic adult rats. Am J Respir Crit Care Med 1997; 156:617-623
8. Veldhuizen RAW, Tremblay LN, Govindarajan A, et al: Pulmonary surfactant is altered during mechanical ventilation of isolated rat lung. Crit Care Med 2000; 28:2545-2551
9. Matalon S, Holm BA, Loewen GM, et al: Sublethal hyperoxic injury to the alveolar epithelium and the pulmonary surfactant system. Exp Lung Res 1988; 14(Suppl): 1021-1033
10. Ward JA, Roberts RJ: Hyperoxia effects on pulmonary pressure: Volume characteristics and lavage surfactant phospholipid in the newborn rabbit. Biol Neonate 1984; 46: 139-148
11. Putman E, Van Golde LM, Haagsman HP: Toxic oxidant species and their impact on the pulmonary surfactant system. Lung 1997; 175:75-103
12. Fisher HK, Clements JA, Tierney DF, et al: Pulmonary effects of paraquat in the first day after injection. Am J Physiol 1975; 228: 1217-1223
13. Holm BA, Notter RH, Siegle J, et al: Pulmonary physiological and surfactant changes during injury and recovery from hyperoxia. J Appl Physiol 1985; 59:1402-1409
14. Tolle A, Kolleck I, Schlame M, et al: Effect of hyperoxia on the composition of the alveolar surfactant and the turnover of surfactant phospholipids, cholesterol, plasmalogens and vitamin E. Biochim Biophys Acta 1997; 1346:198-204
15. Arkovitz MS, Garcia VF, Szabo C, et al: Decreased pulmonary compliance is an early indicator of pulmonary oxygen injury. J Surg Res 1997; 67:193-198
16. Beckman DL, Weiss HS: Hyperoxia compared to surfactant washout on pulmonary compliance in rats. J Appl Physiol 1969; 26:700-709
17. Gilliard N, Heldt GP, Loredo J, et al: Exposure of the hydrophobic components of porcine lung surfactant to oxidant stress alters surface tension properties. J Clin Invest 1994; 93:2608-2615
18. Andersson S, Kheiter A, Merritt TA: Oxidative inactivation of surfactants. Lung 1999; 177: 179-189
19. Lowry OH, Rosebrough NJ, Farr AL, et al: Protein measurement with the Folin reagent. J Biol Chem 1951; 193:265-275
20. Bligh EG, Dyer WJ: A rapid method of total lipid extraction and purification. Can J Biochem Physiol 1959; 37:911-917
21. Duck-Chong CG: A rapid sensitive method for determining phospholipid phosphorus involving digestion with magnesium nitrate. Lipids 1979; 14:492-497
22. Schurch S, Bachofen H, Goerke J, et al: A captive bubble method reproduces the in situ behavior of lung surfactant monolayers. J Appl Physiol 1989; 67:2389-2396
23. Schurch S, Green FH, Bachofen H: Formation and structure of surface films: Captive bubble surfactometry. Biochim Biophys Acta 1998; 1408:180-202
24. Rodriguez-Capote K, Nag K, Schurch S, et al: Surfactant protein interactions with neutral and acidic phospholipid films. Am J Physiol Lung Cell Mol Physiol 2001; 281:L231-L242
25. Gross NJ, Narine KR: Surfactant subtypes of mice: Metabolic relationships and conversion in vitro. J Appl Physiol 1989; 67:414-421
26. Veldhuizen RAW, Hearn SA, Lewis JF, et al: Surface-area cycling of different surfactant preparations: SP-A and SP-B are essential for large-aggregate integrity. Biochem J 1994; 300:519-524
27. Rodriguez-Capote K, McCormack FX, Possmayer F: Pulmonary surfactant protein-A (SP-A) restores the surface properties of surfactant after oxidation by a mechanism that requires the Cys6 interchain disulfide bond and the phospholipid binding domain. J Biol Chem, In Press (e-publication on www.jbc.org)
28. Bailey TC, Cavanagh C, Mehta S, et al: Sepsis and hyperoxia effects on the pulmonary surfactant system in wild-type and iNOS knockout mice. Eur Respir J 2002; 20:177-182
29. Balaan MR, Bowman L, Dedhia HV, et al: Hyperoxia-induced alterations of rat alveolar lavage composition and properties. Exp Lung Res 1995; 21:141-156
30. Wright JR, Hawgood S: Pulmonary surfactant metabolism. Clin Chest Med 1989; 10: 83-93
31. Veldhuizen RAW, Marcou J, Yao L-J, et al: Alveolar surfactant aggregate conversion in ventilated normal and injured rabbits. Am J Physiol 1996; 270:L152-L158
32. Malloy J, Veldhuizen RAW, McCormack FX, et al: Pulmonary surfactant and inflammation in septic adult mice: Role of surfactant protein A. J Appl Physiol 2002; 92:809-816
33. Gross NJ: Surfactant subtypes in experimental lung damage: Radiation pneumonitis. Am J Physiol 1991; 260:L302-L310
34. Putman E, Boere AJF, Van Bree L, et al: Pulmonary surfactant subtype metabolism is altered after short-term ozone exposure. Toxicol Appl Pharmacol 1995; 134:132-138
35. Malloy JL, Veldhuizen RA, Lewis JF: Effects of ventilation on the surfactant system in sepsis-induced lung injury. J Appl Physiol 2000; 88:401-408
36. Holm BA, Venkitaraman AR, Enhorning G, et al: Biophysical inhibition of synthetic lung surfactants. Chem Phys Lipids 1990; 52: 243-250
37. Cockshutt AM, Possmayer F: Lysophosphatidylcholine sensitizes lipid extracts of pulmonary surfactant to inhibition by serum proteins. Biochim Biophys Acta 1991; 1086: 63-71