The physiological changes of cumulative hemorrhagic shock in conscious rats

Journal of Biomedical Science

Volumn 13, Issue 3, 2006, Pages 385-394

  Tai, Chu Peng ^a,b   Kuang, Wen Liao ^c   Hui, Ling Lai ^d   Chao, Yann Fen C ^e   Fwu, Mei Chang ^a   Harn, Horng Jyh ^a,d   Ru, Ping Lee ^a,d  

^a TZU CHI UNIVERSITY   (Taiwan)

^b TZU CHI COLLEGE OF TECHNOLOGY   (Taiwan)

^c NATIONAL CHIAO TUNG UNIVERSITY   (Taiwan)

^d BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

^e NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Animal model; Conscious rats; Cumulative hemorrhage; Lactic acid; Organ injury; Unrestrained

Indexed keywords

CREATINE KINASE; INTERLEUKIN 1BETA; LACTATE DEHYDROGENASE; LACTIC ACID; PENTOBARBITAL; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY CATHETER; ARTICLE; BLEEDING; BLOOD VOLUME; CAUSE OF DEATH; CONSCIOUSNESS; CONTROLLED STUDY; EMERGENCY WARD; FEMORAL ARTERY; HEART RATE; HEMODYNAMICS; HEMORRHAGIC SHOCK; INTRAVENOUS ANESTHESIA; LEUKOCYTE COUNT; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; ORGAN INJURY; PRIORITY JOURNAL; RAT; SURVIVAL;

ANESTHESIA; ANIMALS; BLOOD PRESSURE; CONSCIOUSNESS; CYTOKINES; DISEASE MODELS, ANIMAL; HEART RATE; INTERLEUKIN-1; L-LACTATE DEHYDROGENASE; LACTIC ACID; MALE; RATS; RATS, INBRED WKY; SHOCK, HEMORRHAGIC; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA;

EID: 33646569456     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1007/s11373-005-9065-3     Document Type: Article

References (33)

1. Rixen D., Raum M., Holzgraefe B. et al., A pig hemorrhagic shock model: oxygen debt and metabolic acidemia as indicators of severity. Shock 16: 239-244, 2001.
2. Deitch E.A., Animal models of sepsis and shock: a review and lessons learned. Shock 9: 1-11, 1998.
3. Wiggers C.J., The present status of the shock problem. Physiol. Rev. 22: 74-123, 1942.
4. Chintala M.S. and Jandhyala B.S., Comparative evaluation of the effects of felodipine, hydralazine, and naloxone on the survival rate in rats subjected to a "fixed volume" model of hemorrhagic shock. Circ. Shock 32: 219-229, 1990.
5. Bitterman H., Reissman P., Bitterman N. et al., Oxygen therapy in hemorrhagic shock. Circ. Shock 33: 183-191, 1991.
6. Majde J.A., Animal models for hemorrhage and resuscitation research. J. Trauma 54: s100-s105, 2003.
7. Schadt J.C. and Ludbrook J., Hemodynamic and neurohumoral resposes to acute hypovolemia in conscious mammals. Am. J. Physiol. 260: H305-H318, 1991.
8. Molina P.E., Opiate modulation of hemodynamic, hormonal, and cytokine responses to hemorrhage. Shock 15: 471-478, 2001.
9. McCance K.L. and Huether S.E., Pathophysiology, 4th ed., Mosby, Inc., St. Louis, Missouri USA, 2002, pp. 450-470.
10. Lee R.P., Wang D., Lin N.T. et al., A modified technique for tail-cuff pressure measurement in unrestrained rats at conscious state. J. Biomed. Sci. 9: 424-427, 2002.
11. Van Zutphen L.M.F., Baumans V. and Beynen A.C., Principles of Laboratory Animal Science: a Contribution to the Humane Use and Care of Animals to the Quality of Experiment Results. Elservier, Amsterdam, 1993, pp. 17-74.
12. Takasu A., Prueckner S., Tisherman S.A. et al., Effects of increased oxygen breathing in a volume controlled hemorrhagic shock outcome model in rats. Resuscitation 45: 209-220, 2000.
13. Capone A., Safar P., Stezoski S.W. et al., Uncontrolled hemorrhagic shock outcome model in rats. Resuscitation 29: 143-152, 1995.
14. Marshall H.P. Jr., Capone A., Courcoulas A.P. et al., Effects of hemodilution on long-term survival in an uncontrolled hemorrhagic shock model in rats. J. Trauma 43: 673-679, 1997.
15. Solomonov E., Hirsh M., Yahiya A. et al., The effect of vigorous fluid resuscitation in uncontrolled hemorrhagic shock after massive splenic injury. Crit. Care Med. 28: 749-754, 2000.
16. Raedler C., Voelckel W.G., Wenzel V. et al., Treatment of uncontrolled hemorrhagic shock after liver trauma: fatal effects of fluid resuscitation versus improved outcome after vasopressin. Anesth. Analg. 98: 1759-1766, 2000.
17. Lee R.P., Wang D., Lin N.T. et al., Physiological and chemical indicators for early and late stages of sepsis in conscious rats. J. Biomed. Sci. 9: 613-621, 2002.
18. Singh G., Chaudry K.I. and Chaudry I.H., Crystalloid is as effective as blood in the resuscitation of hemorrhagic shock. Ann. Surg. 215: 377-382, 1992.
19. Flohe S., Ackermann M., Reuter M. et al., Sublethal hemorrhagic shock reduces tumor necrosis factor-alpha-producing capacity in different cell compartments. Eur. Cytokine Netw. 11: 420-426, 2000.
20. Moore K.E. and Murtaugh R.J., Pathophysiologic characteristics of hypovolemic shock. Vet. Clin. North Am. Small Anim. Prac. 31: 1115-1128, 2001.
21. Dunham C.M., Siegel J.H., Weireter L. et al., Oxygen debt and metabolic acidemia as quantitative predictors of mortality and the severity of the ischemic insult in hemorrhagic shock. Crit. Care Med. 19: 231-243, 1991.
22. Claridge J.A., Enelow R.I. and Young J.S., Hemorrhage and resuscitation induce delayed inflammation and pulmonary dysfunction in mice. J. Surg. Res. 92: 206-213, 2000.
23. Bone R.C., Balk R.A., Cerra F.B. et al., Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest 101: 1644-1655, 1992.
24. Marshall J.C., Inflammation, coagulopathy, and the pathogenesis of multiple prgan dysfunction syndrome. Crit. Care Med. 29: s99-s106, 2001.
25. Zingarelli B., Squadrito F., Altavilla D. et al., Role of tumor necrosis factor-alpha in acute hypovolemic hemorrhagic shock in rats. Am. J. Physiol. 266: H1512-1515, 1994.
26. Rhee P., Waxman K., Clark L. et al., Tumor necrosis factor and monocytes are released during hemorrhagic shock. Resuscitation 25: 249-255, 1993.
27. Kelbela I. and Weiss M., Anaesthetics and immune function. Anaesthesiology 14: 685-691, 2001.
28. Kotani N., Hashimoto H., Sessler D.I. et al., Intraoperative modulation of alveolar macrophage function during isoflurane and propofol anesthesia. Anesthesiology 89: 1125-1132, 1998.
29. Kotani N., Hashimoto H., Sessler D.I. et al., Expression of genes for proinflammatory cytokines in alveolar macrophages during propofol and isoflurane anesthesia. Anesth. Analg. 89: 1250-1256, 1999.
30. Xu H., Aibiki M., Yokono S. et al., Dose-depenndent effects of propofol on renal sympathetic nerve activity, blood pressure and heart rate in urethane-anesthetized rabbits. Eur. J. Pharmacol. 387: 79-85, 2000.
31. Loeb A.L., Godeny I. and Longnecker D.E., Anesthestics alter relative contributions of NO and EDHF in rat cremaster muscle microcirculation. Am. J. Physiol. Heart Circ. Physiol. 273: 618-627, 1997.
32. Molina P.E., Noradrenergic inhibition of TNF upregulation in hemorrhagic shock. Neuroimmunomodulation 9: 125-33, 2001.
33. Molina P.E., Malek S., Lang C.H., Qian L., Naukam R. and Abumrad N.N., Early organ-specific hemorrhage-induced increases in tissue cytokine content: associated neurohormonal and opioid alterations. Neuroimmunomodulation 4(1) 28-36, 1997, Jan-Feb.