The Autocrine Motility Factor (AMF) and AMF-receptor Combination Needs Sugar Chain Recognition Ability and Interaction Using the C-terminal Region of AMF

Journal of Molecular Biology

Volumn 358, Issue 3, 2006, Pages 741-753

  Haga, Arayo ^a   Tanaka, Nobutada ^b   Funasaka, Tatsuyoshi ^a,c   Hashimoto, Kazunori ^a   Nakamura, Kazuo T ^b   Watanabe, Hideomi ^d   Raz, Avraham ^c   Nagase, Hisamitsu ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^b SHOWA UNIVERSITY   (Japan)

^c WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d GUNMA UNIVERSITY   (Japan)

Author keywords

AMF; AMFR; glyco chain; point mutation

Indexed keywords

AMINO ACID; AUTOCRINE MOTILITY FACTOR; AUTOCRINE MOTILITY FACTOR RECEPTOR; ENZYME INHIBITOR; FUNCTIONAL GROUP; GLUCOSE 6 PHOSPHATE ISOMERASE; GLUCOSIDASE; MUTANT PROTEIN; PHOSPHATE; RECOMBINANT PROTEIN; SUGAR;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CELL MIGRATION; CELL MOTILITY; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BINDING; ENZYME SUBSTRATE; EXTRACELLULAR SPACE; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING; RECEPTOR UPREGULATION; SENSITIVITY ANALYSIS; SITE DIRECTED MUTAGENESIS; WILD TYPE;

EID: 33646487483     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2006.02.046     Document Type: Article

References (46)

1. Liotta L.A., Mandler R., Murano G., Katz D.A., Gordon R.K., Chiang P.K., and Schiffmann E. Tumor cell autocrine motility factor. Proc. Natl Acad. Sci. USA 83 (1986) 3302-3306
2. Nabi I.R., Watanabe H., and Raz A. Autocrine motility factor and its receptor: role in cell locomotion and metastasis. Cancer Metastasis Rev. 11 (1992) 5-20
3. Watanabe H., Takehama K., Date M., Shinozaki T., and Raz A. Tumor cell motility factor is the neuroleukin/phosphohexose isomerase polypeptide. Cancer Res. 56 (1996) 2960-2963
4. Niinaka Y., Paku S., Haga A., Watanabe H., and Raz A. Expression and secretion of neuroleukin/phosphohexose isomerase/maturation factor as autocrine motility factor by tumor cells. Cancer Res. 58 (1998) 2667-2674
5. Haga A., Niinaka Y., and Raz A. Phosphohexose isomerase/autocrine motility factor/neuroleukin/maturation factor is a multifunctional phosphoprotein. Biochim. Biophys. Acta 1480 (2000) 235-244
6. Nabi I.R., and Raz A. Cell shape modulation alters glycosylation of a metastatic melanoma cell-shape antigen. Int. J. Cancer 40 (1980) 396-402
7. Nabi I.R., and Raz A. Loss of metastatic responsiveness to cell shape modulation in a newly characterized B16 melanoma adhesive variant. Cancer Res. 48 (1987) 1258-1264
8. Watanabe H., Nabi I.R., and Raz A. The relationship between motility factor receptor internalization and the lung colonization capacity of murine melanoma cells. Cancer Res. 51 (1991) 2699-2705
9. Benlimame N., Le P.U., and Nabi I.R. Localization of autocrine motility factor receptor to caveolae and clathrin-independent internalization of its ligand to smooth endoplasmic reticulum. Mol. Biol. Cell 9 (1998) 1773-1786
10. Wang H.J., Benlimame N., and Nabi I.R. The AMF-R tubule is a smooth ilimaquinone-sensitive subdomain of the endoplasmic reticulum. J. Cell Sci. 110 (1997) 3043-3053
11. Shimizu K., Tani M., Watanabe H., Nagamachi Y., Niinaka Y., Shiroishi T., et al. The autocrine motility factor gene encodes a novel type of seven transmembrane protein. FEBS Letters 456 (1999) 295-300
12. Nabi I.R., Watanabe H., and Raz A. Identification of B16-F1 melanoma autocrine motility-like factor receptor. Cancer Res. 50 (1990) 409-414
13. Sun Y.J., Chou C.C., Chen W.S., Wu R.T., Meng M., and Hsiao C.D. The crystal structure of a multifunctional protein: phosphoglucose isomerase/autocrine motility factor/neuroleukin. Proc. Natl Acad. Sci. USA 96 (1999) 5412-5417
14. Chou C.C., Sun Y.J., Meng M., and Hsiao C.D. The crystal structure of phosphoglucose isomerase/autocrine motility factor/neuroleukin complexed with its carbohydrate phosphate inhibitors suggests its substrate/receptor recognition. J. Biol. Chem. 275 (2000) 23154-23160
15. Jeffery C.J., Bahnson B.J., Chein W., Ringe D., and Petsko G.A. Crystal structure of rabbit phosphoglucose isomerase, a glycolytic enzyme that moonlights as neuroleukin, autocrine motility factor, and differentiation mediator. Biochemistry 39 (2000) 955-964
16. Lee J.H., Chang K.Z., Patel V., and Jeffery C.J. Crystal structure of rabbit phosphoglucose isomerase complexed with its substrate d-fructose 6-phosphate. Biochemistry 40 (2001) 7799-7805
17. Muirhead H., and Shaw P.J. Three-dimensional structure of pig muscle phosphoglucose isomerase at 6 Å resolution. J. Mol. Biol. 89 (1974) 195-203
18. Shaw P.J., and Muirhead H. Crystallographic structure analysis of glucose 6-phosphate isomerase at 3.5 Å resolution. J. Mol. Biol. 109 (1977) 475-485
19. Read J., Pearce J., Li X., Muirhead H., Chirgwin J., and Davies C. The crystal structure of human phosphoglucose isomerase at 1.6 Å resolution: implications for catalytic mechanism, cytokine activity and haemolytic anaemia. J. Mol. Biol. 309 (2001) 447-463
20. Tanaka N., Haga A., Uemura H., Akiyama H., Funasaka T., Nagase H., et al. Inhibition mechanism of cytokine activity of human autocrine motility factor examined by crystal structure analysis and site-directed mutagenesis studies. J. Mol. Biol. 318 (2002) 985-997
21. Tanaka N., Haga A., Naba N., Shiraiwa K., Kusakabe Y., Hashimoto K., et al. Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure activity relationship of the inhibitors. J. Mol. Biol. 356 (2006) 312-324
22. Funasaka T., Haga A., Raz A., and Nagase H. Tumor autocrine motility factor is an angiogenic factor that stimulates endothelial cell motility. Biochem. Biophys. Res. Commun. 284 (2001) 1116-1125
23. Funasaka T., Haga A., Raz A., and Nagase H. Tumor autocrine motility factor induces hyperpermeability of endothelial and mesothelial cells leading to accumulation of ascites fluid. Biochem. Biophys. Res. Commun. 293 (2002) 192-200
24. Haga A., Funasaka T., Niinaka Y., Raz A., and Nagase H. The autocrine motility factor signaling induces tumor apoptotic resistance which regulates apoptosome expression. Int. J. Cancer 105 (2003) 707-714
25. Imai Y., Matsushima Y., Sugimura T., and Terada M. A simple and rapid for generating a deletion by PCR. Nucl. Acid Res. 19 (1991) 2785
26. Meng M., Chen Y.T., Hsiao Y.Y., Itoh Y., and Bagdasarian M. Mutational analysis of the conserved cationic residues of Bacillus stearothermophilus 6-phosphoglucose isomerase. Eur. J. Biochem. 257 (1998) 500-505
27. Fang S., Ferrone M., Yang C., Jensen J.P., Tiwari S., and Weissman A.M. The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum. Proc. Natl Acad. Sci. USA 98 (2001) 14422-14427
28. Yanagawa T., Funasaka T., Tsutsumi S., Raz T., Tanaka N., and Raz A. Diffential regulation of phosphoglucose isomerase/autocrine motility factor activities by protein kinase CK2 phosphorylation. J. Biol. Chem. 280 (2005) 10419-10426
29. Niinaka Y., Haga A., Negishi A., Yoshimasu H., Raz A., and Amagasa T. Regulation of cell motility via high and low affinity autocrine motility factor (AMF) receptor in human oral squamous carcinoma cells. Oral Oncol. 38 (2002) 49-55
30. Meng M., Chane T.L., Sun Y.J., and Hsiao C.D. Probing the location and function of the conserved histidine residue of phosphoglucose isomerase by using an active site directed inhibitor N-bromoacetylethanolamine phosphate. Protein Sci. 8 (1999) 2438-2443
31. Meng M., Lin H.Y., Hsieh C.J., and Chen Y.T. Functions of the conserved anionic amino acids and those interacting with the substrate phosphate group of phosphoglucose isomerase. FEBS Letters 499 (2001) 11-14
32. Walker J., Crowley P., Moreman A.D., and Barrett J. Biochemical properties of cloned glutathione S-transferases from Schistosoma mansoni and Schistosoma japonicum. Mol. Biochem. Parasitol. 61 (1993) 255-264
33. Tsutsumi S., Gupta S.K., Hogan V., Tanaka N., Nakamura K.T., Nabi I.R., and Raz A. The enzymatic activity of phosphoglucose isomerase is not required for its cytokine function. FEBS Letters 534 (2003) 49-53
34. Allouche M., Sahraoui Y., Augery-Bourget Y., Perrakis M., Jasmin C., and Georgoulias V. Interleukin 2 receptors. Leuk. Res. 14 (1990) 699-703
35. Ahmed A., Dunk C., Ahmad S., and Khaliq A. Regulation of placental vascular endothelial growth factor (VEGF) and placenta growth factor (PIGF) and soluble Flt-1 by oxygen-a review. Placenta 21 (2000) S16-S24
36. Amraei M., and Nabi I.R. Species specificity of the cytokine function of phosphoglucose isomerase. FEBS Letters 525 (2002) 151-155
37. Alber T. Structure of the leucine zipper. Curr. Opin. Genet. Dev. 2 (1992) 205-210
38. Kohn E.C., Liotta L.A., and Schiffmann E. Autocrine motility factor stimulates a three fold increase in inositol trisphosphate in human melanoma cells. Biochem. Biophys. Res. Commun. 166 (1990) 757-764
39. Silletti S., Timar J., Honn K.V., and Raz A. Autocrine motility factor induces differential 12-lipoxygenase expression and activity in high- and low-metastatic K1735 melanoma cell variants. Cancer Res. 54 (1994) 5752-5756
40. Funasaka T., Haga A., Raz A., and Nagase H. Autocrine motility factor secreted by tumor cells upregulates vascular endothelial growth factor receptor (Flt-1) expression in endothelial cells. Int. J. Cancer 101 (2002) 217-223
41. Tsutsumi S., Gupta S.K., Hogan V., Collard J.G., and Raz A. Activation of small GTPase Rho is required for autocrine motility factor signaling. Cancer Res. 62 (2002) 4484-4490
42. Silletti S., Watanabe H., Hogan V., Nabi I.R., and Raz A. Purification of B16-F1 melanoma autocrine motility factor and its receptor. Cancer Res. 51 (1991) 3507-3511
43. Landt O., Grunert H.P., and Hahn U. A general method for rapid site-directed mutagenesis using the polymerase chain reaction. Gene 96 (1990) 125-128
44. Garcy R.W., and Tilley B.E. Phosphoglucose isomerase of human erythrocytes and cardiac tissue. Methods Enzymol. 41 (1975) 392-400
45. DeLorenzo R.J., and Ruddle F.H. Genetic control of two electrophoretic variants of glucosephosphate isomerase in the mouse (Mus musculus). Biochem. Genet. 3 (1969) 151-162
46. Harrison R.A.P. The detection of hexokinase, glucosephosphate isomerase and phosphoglucomutase activities in polyacrylamide gel after electrophoresis: a novel method using immobilized glucose 6-phosphate dehydrogenase. Anal. Biochem. 61 (1974) 500-507