Inhibition mechanism of cytokine activity of human autocrine motility factor examined by crystal structure analyses and site-directed mutagenesis studies

Journal of molecular biology

Volumn 318, Issue 4, 2002, Pages 985-997

  Tanaka, Nobutada ^a   Haga, Arayo ^b   Uemura, Hiroshi ^a   Akiyama, Hiroko ^a   Funasaka, Tatsuyoshi ^b   Nagase, Hisamitsu ^b   Raz, Avraham ^c   Nakamura, Kazuo T ^a  

^a SHOWA UNIVERSITY   (Japan)

^b GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^c WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOCRINE MOTILITY FACTOR; CROSS LINKING REAGENT; ERYTHROSE 4 PHOSPHATE; ERYTHROSE 4-PHOSPHATE; SUGAR PHOSPHATE;

ARTICLE; BINDING SITE; CELL CULTURE; CHEMICAL STRUCTURE; CHEMISTRY; CIRCULAR DICHROISM; DRUG ANTAGONISM; ENZYME SPECIFICITY; GENETICS; HUMAN; PROTEIN CONFORMATION; SITE DIRECTED MUTAGENESIS; WESTERN BLOTTING; X RAY CRYSTALLOGRAPHY;

AUTOCRINE MOTILITY FACTOR; BINDING SITES; BLOTTING, WESTERN; CIRCULAR DICHROISM; CROSS-LINKING REAGENTS; CRYSTALLOGRAPHY, X-RAY; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; SUBSTRATE SPECIFICITY; SUGAR PHOSPHATES; TUMOR CELLS, CULTURED;

EID: 0037053450     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(02)00186-9     Document Type: Article

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