MS-binding assays: Kinetic, saturation, and competitive experiments based on quantitation of bound marker as exemplified by the GABA transporter mGAT1

ChemMedChem

Volumn 1, Issue 2, 2006, Pages 208-217

  Zepperitz, Christine ^a   Höfner, Georg ^a   Wanner, Klaus T ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

Drug screening; GABA transporters; Ligand binding assays; Liquid chromatography; Mass spectrometry

Indexed keywords

4 AMINOBUTYRIC ACID CARRIER;

ARTICLE; ELECTROSPRAY MASS SPECTROMETRY; KINETICS; LIQUID CHROMATOGRAPHY; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RADIOASSAY; REPRODUCIBILITY;

CHROMATOGRAPHY, LIQUID; GABA PLASMA MEMBRANE TRANSPORT PROTEINS; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; RADIOLIGAND ASSAY; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 33646486086     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.200500038     Document Type: Article

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