-
1
-
-
0028913012
-
Hydroxyurea for patients with essential thrombocythemia and a high risk of thrombosis
-
Cortelazzo S, Finazzi G, Ruggeri M, et al. Hydroxyurea for patients with essential thrombocythemia and a high risk of thrombosis. N Engl J Med 1995;332:1132-1136
-
(1995)
N Engl J Med
, vol.332
, pp. 1132-1136
-
-
Cortelazzo, S.1
Finazzi, G.2
Ruggeri, M.3
-
2
-
-
0031982894
-
Acute myeloid leukemia and myelodysplastic syndromes following essential thrombocythemia treated with hydroxyurea: High proportion of cases with 17p deletion
-
Sterkers Y, Preudhomme C, Lai JL, et al. Acute myeloid leukemia and myelodysplastic syndromes following essential thrombocythemia treated with hydroxyurea: high proportion of cases with 17p deletion. Blood 1998;91:616-622
-
(1998)
Blood
, vol.91
, pp. 616-622
-
-
Sterkers, Y.1
Preudhomme, C.2
Lai, J.L.3
-
3
-
-
0030811932
-
Therapeutic dilemmas: Balancing the risks of bleeding, thrombosis, and leukemic transformation in myeloproliferative disorders (MPD)
-
Murphy S. Therapeutic dilemmas: balancing the risks of bleeding, thrombosis, and leukemic transformation in myeloproliferative disorders (MPD). Thromb Haemost 1997;78: 622-626
-
(1997)
Thromb Haemost
, vol.78
, pp. 622-626
-
-
Murphy, S.1
-
4
-
-
0033781129
-
Second malignancies in patients with essential thrombocythaemia treated with busulphan and hydroxyurea: Long-term follow-up of a randomized clinical trial
-
Finazzi G, Ruggeri M, Rodeghiero F, Barbui T. Second malignancies in patients with essential thrombocythaemia treated with busulphan and hydroxyurea: long-term follow-up of a randomized clinical trial. Br J Haematol 2000;110:577-583
-
(2000)
Br J Haematol
, vol.110
, pp. 577-583
-
-
Finazzi, G.1
Ruggeri, M.2
Rodeghiero, F.3
Barbui, T.4
-
6
-
-
14744274434
-
Anagrelide: Analysis of long-term safety and leukemogenic potential in myeloproliferative disorders
-
Fruchtman SM, Petitt RM, Gilbert HS, Fiddler S. Anagrelide: analysis of long-term safety and leukemogenic potential in myeloproliferative disorders. Leukemia Research 2005;29: 481-491
-
(2005)
Leukemia Research
, vol.29
, pp. 481-491
-
-
Fruchtman, S.M.1
Petitt, R.M.2
Gilbert, H.S.3
Fiddler, S.4
-
7
-
-
2442666009
-
Anagrelide: Analysis of long term safety and leukemogenic potential in Myeloproliferative Diseases (MPDs)
-
Fruchtman SM, Petitt RM, Gilbert HS, et al. Anagrelide: Analysis of Long Term Safety and Leukemogenic Potential in Myeloproliferative Diseases (MPDs). Blood 2002;100:xxx (abst)
-
(2002)
Blood
, vol.100
-
-
Fruchtman, S.M.1
Petitt, R.M.2
Gilbert, H.S.3
-
8
-
-
21444434751
-
Hydroxyurea compared with anagrelide in high-risk essential thrombocythemia
-
Harrison CN, Campbell PJ, Buck G, et al. Hydroxyurea compared with anagrelide in high-risk essential thrombocythemia. N Engl J Med 2005;353:33-45
-
(2005)
N Engl J Med
, vol.353
, pp. 33-45
-
-
Harrison, C.N.1
Campbell, P.J.2
Buck, G.3
-
10
-
-
0035061393
-
Increased circulating platelet-leukocyte aggregates in myeloproliferative disorders is correlated to previous thrombosis, platelet activation and platelet count
-
Jensen MK, de Nully BP, Lund BV, Nielsen OJ, Hasselbalch HC. Increased circulating platelet-leukocyte aggregates in myeloproliferative disorders is correlated to previous thrombosis, platelet activation and platelet count. Eur J Haematol 2001;66:143-151
-
(2001)
Eur J Haematol
, vol.66
, pp. 143-151
-
-
Jensen, M.K.1
De Nully, B.P.2
Lund, B.V.3
Nielsen, O.J.4
Hasselbalch, H.C.5
-
11
-
-
0034672149
-
Polymorphonuclear leukocyte activation and hemostasis in patients with essential thrombocythemia and polycythemia vera
-
Falanga A, Marchetti M, Evangelista V, et al. Polymorphonuclear leukocyte activation and hemostasis in patients with essential thrombocythemia and polycythemia vera. Blood 2000;96:4261-4266
-
(2000)
Blood
, vol.96
, pp. 4261-4266
-
-
Falanga, A.1
Marchetti, M.2
Evangelista, V.3
-
12
-
-
17844390356
-
Leukocyte-platelet interaction in patients with essential thrombocythemia and polycythemia vera
-
Falanga A, Marchetti M, Vignoli A, Balducci D, Barbui T. Leukocyte-platelet interaction in patients with essential thrombocythemia and polycythemia vera. Exp Hematol 2005;33: 523-530
-
(2005)
Exp Hematol
, vol.33
, pp. 523-530
-
-
Falanga, A.1
Marchetti, M.2
Vignoli, A.3
Balducci, D.4
Barbui, T.5
-
13
-
-
17444444006
-
Increased CD11b neutrophil expression in Budd-Chiari syndrome or portal vein thrombosis secondary to polycythaemia vera
-
Alvarez-Larran A, Garcia-Pagan JC, Abraldes JG, et al. Increased CD11b neutrophil expression in Budd-Chiari syndrome or portal vein thrombosis secondary to polycythaemia vera. Br J Haematol 2004;124:329-335
-
(2004)
Br J Haematol
, vol.124
, pp. 329-335
-
-
Alvarez-Larran, A.1
Garcia-Pagan, J.C.2
Abraldes, J.G.3
-
14
-
-
0018877710
-
Inhibition of platelet function by antithrombotic agents which selectively inhibit low-Km cyclic 3′,5′-adenosine monophosphate phosphodiesterase
-
Tang SS, Frojmovic MM. Inhibition of platelet function by antithrombotic agents which selectively inhibit low-Km cyclic 3′,5′-adenosine monophosphate phosphodiesterase. J Lab CUn Med 1980;95:241-257
-
(1980)
J Lab CUn Med
, vol.95
, pp. 241-257
-
-
Tang, S.S.1
Frojmovic, M.M.2
-
15
-
-
0018647310
-
A potent new inhibitor of platelet aggregation and experimental thrombosis, anagrelide (BL-4162A)
-
Fleming JS, Buyniski JP. A potent new inhibitor of platelet aggregation and experimental thrombosis, anagrelide (BL-4162A). Thromb Res 1979;15:373-388
-
(1979)
Thromb Res
, vol.15
, pp. 373-388
-
-
Fleming, J.S.1
Buyniski, J.P.2
-
16
-
-
0026576978
-
Effect of anagrelide on platelet count and function in patients with thrombocytosis and myeloproliferative disorders
-
Balduini CL, Bertolino G, Noris P, Ascari E. Effect of anagrelide on platelet count and function in patients with thrombocytosis and myeloproliferative disorders. Haematologica 1992;77:40-43
-
(1992)
Haematologica
, vol.77
, pp. 40-43
-
-
Balduini, C.L.1
Bertolino, G.2
Noris, P.3
Ascari, E.4
-
17
-
-
0033003618
-
Studies of platelet volume, chemistry and function in patients with essential thrombocythaemia treated with anagrelide
-
Bellucci S, Legrand C, Boval B, Drouet L, Caen J. Studies of platelet volume, chemistry and function in patients with essential thrombocythaemia treated with anagrelide. Br J Haematol 1999;104:886-892
-
(1999)
Br J Haematol
, vol.104
, pp. 886-892
-
-
Bellucci, S.1
Legrand, C.2
Boval, B.3
Drouet, L.4
Caen, J.5
-
18
-
-
0035865604
-
Long-term use of anagrelide in young patients with essential thrombocythemia
-
Storen EC, Tefferi A. Long-term use of anagrelide in young patients with essential thrombocythemia. Blood 2001;97:863-866
-
(2001)
Blood
, vol.97
, pp. 863-866
-
-
Storen, E.C.1
Tefferi, A.2
-
19
-
-
4344605780
-
Anagrelide: A decade of clinical experience with its use for the treatment of primary thrombocythaemia
-
Petrides PE. Anagrelide: a decade of clinical experience with its use for the treatment of primary thrombocythaemia. Expert Opin Pharmacother 2004;5:1781-1798
-
(2004)
Expert Opin Pharmacother
, vol.5
, pp. 1781-1798
-
-
Petrides, P.E.1
-
20
-
-
0032926216
-
Treatment of essential thrombocythemia with anagrelide
-
Silverstein MN, Tefferi A. Treatment of essential thrombocythemia with anagrelide. Semin Hematol 1999;36:23-25
-
(1999)
Semin Hematol
, vol.36
, pp. 23-25
-
-
Silverstein, M.N.1
Tefferi, A.2
-
21
-
-
0242299236
-
Anagrelide-induced bone marrow changes during therapy of chronic myeloproliferative disorders with thrombocytosis. An immunohistochemical and morphometric study of sequential trephine biopsies
-
Thiele J, Kvasnicka HM, Fuchs N, et al. Anagrelide-induced bone marrow changes during therapy of chronic myeloproliferative disorders with thrombocytosis. an immunohistochemical and morphometric study of sequential trephine biopsies. Haematologica 2003;88:1130-1138
-
(2003)
Haematologica
, vol.88
, pp. 1130-1138
-
-
Thiele, J.1
Kvasnicka, H.M.2
Fuchs, N.3
-
22
-
-
0035983219
-
Variation of PDGF, TGFbeta, and bFGF levels in essential thrombocythemia patients treated with anagrelide
-
Lev PR, Marta RF, Vassallu P, Molinas FC. Variation of PDGF, TGFbeta, and bFGF levels in essential thrombocythemia patients treated with anagrelide. Am J Hematol 2002;70:85-91
-
(2002)
Am J Hematol
, vol.70
, pp. 85-91
-
-
Lev, P.R.1
Marta, R.F.2
Vassallu, P.3
Molinas, F.C.4
-
23
-
-
13244258484
-
PDGF-A, PDGF-B, TGFbeta, and bFGF mRNA levels in patients with essential thrombocythemia treated with anagrelide
-
Lev PR, Salim JP, Kornblihtt LI, et al. PDGF-A, PDGF-B, TGFbeta, and bFGF mRNA levels in patients with essential thrombocythemia treated with anagrelide. Am J Hematol 2005;78:155-157
-
(2005)
Am J Hematol
, vol.78
, pp. 155-157
-
-
Lev, P.R.1
Salim, J.P.2
Kornblihtt, L.I.3
-
24
-
-
0033982364
-
Effects of interferon and hydroxyurea on bone marrow fibrosis in chronic myelogenous leukaemia: A comparative retrospective multicentre histological and clinical study
-
Thiele J, Kvasnicka HM, Schmitt-Graeff A, et al. Effects of interferon and hydroxyurea on bone marrow fibrosis in chronic myelogenous leukaemia: a comparative retrospective multicentre histological and clinical study. Br J Haematol 2000;108:64-71
-
(2000)
Br J Haematol
, vol.108
, pp. 64-71
-
-
Thiele, J.1
Kvasnicka, H.M.2
Schmitt-Graeff, A.3
-
26
-
-
20144363192
-
Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
-
Baxter EJ, Scott LM, Campbell PJ, et al. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet 2005;365:1054-1061
-
(2005)
Lancet
, vol.365
, pp. 1054-1061
-
-
Baxter, E.J.1
Scott, L.M.2
Campbell, P.J.3
-
27
-
-
17844383458
-
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
-
James C, Ugo V, Le Couedic JP, et al. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature 2005;434:1144-1148
-
(2005)
Nature
, vol.434
, pp. 1144-1148
-
-
James, C.1
Ugo, V.2
Le Couedic, J.P.3
-
28
-
-
17644424955
-
A gain-of-function mutation of JAK2 in myeloproliferative disorders
-
Kralovics R, Passamonti F, Buser AS, et al. A gain-of-function mutation of JAK2 in myeloproliferative disorders. N Engl J Med 2005;352:1779-1790
-
(2005)
N Engl J Med
, vol.352
, pp. 1779-1790
-
-
Kralovics, R.1
Passamonti, F.2
Buser, A.S.3
-
29
-
-
20244369569
-
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
-
Levine RL, Wadleigh M, Cools J, et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell 2005;7:387-397
-
(2005)
Cancer Cell
, vol.7
, pp. 387-397
-
-
Levine, R.L.1
Wadleigh, M.2
Cools, J.3
-
30
-
-
20744460045
-
Identification of an acquired JAK2 mutation in Polycythemia vera
-
Zhao R, Xing S, Li Z, et al. Identification of an acquired JAK2 mutation in Polycythemia vera. J Biol Chem 2005; 280:22788-22792
-
(2005)
J Biol Chem
, vol.280
, pp. 22788-22792
-
-
Zhao, R.1
Xing, S.2
Li, Z.3
-
31
-
-
28244442441
-
Definition of subtypes of essential thrombocythaemia and relation to polycythaemia vera based on JAK2 V617F mutation status: A prospective study
-
Campbell PJ, Scott LM, Buck G, et al. Definition of subtypes of essential thrombocythaemia and relation to polycythaemia vera based on JAK2 V617F mutation status: a prospective study. Lancet 2005;366:1945-1953
-
(2005)
Lancet
, vol.366
, pp. 1945-1953
-
-
Campbell, P.J.1
Scott, L.M.2
Buck, G.3
-
32
-
-
0037528684
-
Efficacy and safety of long-term use of hydroxyurea in young patients with essential thrombocythemia and a high risk of thrombosis
-
letter
-
Finazzi G, Ruggeri M, Rodeghiero F, Barbui T. Efficacy and safety of long-term use of hydroxyurea in young patients with essential thrombocythemia and a high risk of thrombosis. Blood 2003;101:3749 (letter)
-
(2003)
Blood
, vol.101
, pp. 3749
-
-
Finazzi, G.1
Ruggeri, M.2
Rodeghiero, F.3
Barbui, T.4
-
33
-
-
24944520130
-
Essential thrombocythaemia: Challenges and evidence-based management
-
Harrison CN. Essential thrombocythaemia: challenges and evidence-based management. Br J Haematol 2005;130:153-165
-
(2005)
Br J Haematol
, vol.130
, pp. 153-165
-
-
Harrison, C.N.1
-
34
-
-
2942579910
-
Practice guidelines for the therapy of essential thrombocythemia. A statement from the Italian Society of Hematology, the Italian Society of Experimental Hematology and the Italian Group for Bone Marrow Transplantation
-
Barbui T, Barosi G, Grossi A, et al. Practice guidelines for the therapy of essential thrombocythemia. A statement from the Italian Society of Hematology, the Italian Society of Experimental Hematology and the Italian Group for Bone Marrow Transplantation. Haematologica 2004;89:215-232
-
(2004)
Haematologica
, vol.89
, pp. 215-232
-
-
Barbui, T.1
Barosi, G.2
Grossi, A.3
-
35
-
-
13444256042
-
Thrombosis and haemorrhage in polycythaemia vera and essential thrombocythaemia
-
Elliott MA, Teffer A. Thrombosis and haemorrhage in polycythaemia vera and essential thrombocythaemia. Br J Haemost 2005;128:275-290
-
(2005)
Br J Haemost
, vol.128
, pp. 275-290
-
-
Elliott, M.A.1
Teffer, A.2
|