Synthesis of new pyridazinone derivatives and their affinity towards α1-α2-adrenoceptors

Bioorganic and Medicinal Chemistry

Volumn 7, Issue 5, 1999, Pages 933-941

  Corsano, Stefano ^a   Strappaghetti, Giovannella ^a   Barbaro, Roberta ^a   Giannaccini, Gino ^b   Betti, Laura ^b   Lucacchini, Antonio ^b  

^a UNIVERSITY OF PERUGIA   (Italy)

^b UNIVERSITY OF PISA   (Italy)

Author keywords

1 arylpiperazine and RAS; Affinity 1, 2 blocking; DMF=N,N Dimethylformamide; Pyridazinone; TBAB=tetrabutyl ammonium bromide

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR; PRAZOSIN; PYRIDAZINONE DERIVATIVE; RAUWOLSCINE;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BRAIN CORTEX; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; LIGAND BINDING; NONHUMAN; RADIOASSAY; RAT; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

ANIMALS; CEREBRAL CORTEX; KINETICS; MODELS, CHEMICAL; PYRIDAZINES; RATS; RECEPTORS, ADRENERGIC, ALPHA-1; RECEPTORS, ADRENERGIC, ALPHA-2;

EID: 0033135084     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(99)00046-2     Document Type: Article

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